|
| Status |
Public on Nov 30, 2018 |
| Title |
IDH3a KO effect on global DNA methylation |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
IDH3a KO in NHAs was demonstrated to exert global DNA methylation changes. These studies were followed by an Illumina EPIC methylation array to evaluate the location of differentially methylated CpGs
|
| |
|
| Overall design |
4 biological replicates for each condition (IDH3a wild-type vs. CRISPR/Cas9 KO) were used and gDNA was extracted. gDNA was then analyzed via an Illumina EPIC methylation array chip
|
| |
|
| Contributor(s) |
May JL, Stegh AH, Ji Y |
| Citation(s) |
30613765 |
| |
| Submission date |
Jun 05, 2018 |
| Last update date |
Jan 20, 2019 |
| Contact name |
Yanrong Ji |
| E-mail(s) |
[email protected]
|
| Organization name |
Northwestern University
|
| Department |
Feinberg School of Medicine
|
| Lab |
Davuluri Lab
|
| Street address |
Arthur J. Rubloff Building, 750 North Lake Shore Drive, 11th Floor
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60611 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA474738 |
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