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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jul 31, 2019 |
| Title |
lncRNA SYISL contributes to the genome-wide expression during myogenic differentiation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
In order to screen the target genes regulated by SYISL,we transfected the siRNA to knock down SYISL gene (si-SYISL) and negative control siRNA (si-NC), induced cells to differentiate for 2 days. The results suggest that SYISL knockdown broadly inhibits cell cycle genes expression, and promotes myogenic differentiation-associated genes expression.
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| Overall design |
We further transfected the siRNA to knock down SYISL gene (si-SYISL) and induced cells to differentiate for 2 days. Then, we used microarray to analyze genome-wide gene changes after SYISL knockdown in C2C12 cells differentiated for 2 days.
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| Contributor(s) |
Bo Z, Jun JJ, Wei L, Pan X |
| Citation(s) |
30279181 |
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| Submission date |
Jul 31, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
lvwei jian jun |
| E-mail(s) |
[email protected]
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| Phone |
13212798453
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| Organization name |
huazhong agriculture university
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| Department |
College of Animal science and technology
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| Street address |
shizishan street, NO.1
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| City |
Wuhan |
| State/province |
Hubei |
| ZIP/Postal code |
430070 |
| Country |
China |
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| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (6)
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| GSM2723631 |
C2C12 cells, differentiation for 2 days, si-NC, replicate 1 |
| GSM2723632 |
C2C12 cells, differentiation for 2 days, si-NC, replicate 2 |
| GSM2723633 |
C2C12 cells, differentiation for 2 days, si-NC, replicate 3 |
| GSM2723634 |
C2C12 cells, differentiation for 2 days, si-SYISL, replicate 1 |
| GSM2723635 |
C2C12 cells, differentiation for 2 days, si-SYISL, replicate 2 |
| GSM2723636 |
C2C12 cells, differentiation for 2 days, si-SYISL, replicate 3 |
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| Relations |
| BioProject |
PRJNA396562 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE102087_RAW.tar |
13.2 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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