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    CG34417 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34417provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085446
    Locus tag
    Dmel_CG34417
    See related
    AllianceGenome:FB:FBgn0085446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH23906; CG3950; CG3960; Dmel\CG34417
    Old locus tag
    CG3950; CG3960; Dmel_CG3950; Dmel_CG3960
    Summary
    Predicted to be involved in actin cytoskeleton organization. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. Is expressed in adult head; adult heart; larval muscle system; larval somatic muscle cell; and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34417 in Genome Data Viewer
    Location:
    6B2-6C1; 1-17 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6540771..6589173)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6434804..6483206)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ribosomal protein L7A Neighboring gene deltex Neighboring gene long non-coding RNA:CR43832 Neighboring gene uncharacterized protein Neighboring gene Protein interacting with APP tail-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mediator complex subunit Med19 binds directly GATA transcription factors and is required with Med1 for GATA-driven gene regulation in vivo. Immarigeon C, et al. J Biol Chem, 2020 Sep 25. PMID 32737196, Free PMC Article
    2. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Casad ME, et al. Mol Genet Genomics, 2012 Apr. PMID 22398840, Free PMC Article
    3. Specific SR protein-dependent splicing substrates identified through genomic SELEX. Kim S, et al. Nucleic Acids Res, 2003 Apr 1. PMID 12655012, Free PMC Article
    4. Natural genetic variation in Drosophila melanogaster reveals genes associated with Coxiella burnetii infection. Guzman RM, et al. Genetics, 2021 Mar 31. PMID 33789347, Free PMC Article
    5. Mes2, a MADF-containing transcription factor essential for Drosophila development. Zimmermann G, et al. Dev Dyn, 2006 Dec. PMID 17029287

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mesoderm development NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34417-PC
    CG34417-PD
    CG34417-PF
    CG34417-PH
    CG34417-PI
    CG34417-PJ
    CG34417-PK
    CG34417-PL
    CG34417-PM
    CG34417-PN
    CG34417-PO
    CG34417-PP
    CG34417-PQ
    CG34417-PR
    CG34417-PS
    CG34417-PT
    CG34417-PU
    CG34417-PV
    CG34417-PW
    CG34417-PX
    CG34417-PY

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      6540771..6589173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169208.3 → NP_001162679.1  uncharacterized protein Dmel_CG34417, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162679.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2QD99
      Conserved Domains (2) summary
      cd00014
      Location:3435 → 3538
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3169 → 3218
      Smoothelin; Smoothelin cytoskeleton protein

    2. NM_001272350.1 → NP_001259279.1  uncharacterized protein Dmel_CG34417, isoform Q [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259279.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PH75
      Conserved Domains (1) summary
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein

    3. NM_001272354.1 → NP_001259283.1  uncharacterized protein Dmel_CG34417, isoform U [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259283.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV00
      Conserved Domains (3) summary
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3857 → 3868
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3810 → 3882
      GBP_C; Guanylate-binding protein, C-terminal domain

    4. NM_001169209.3 → NP_001162680.1  uncharacterized protein Dmel_CG34417, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162680.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV00
      Conserved Domains (3) summary
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3857 → 3868
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3810 → 3882
      GBP_C; Guanylate-binding protein, C-terminal domain

    5. NM_001272353.1 → NP_001259282.1  uncharacterized protein Dmel_CG34417, isoform T [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259282.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PDW8
      Conserved Domains (4) summary
      cd00014
      Location:5076 → 5179
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3857 → 3868
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3810 → 3882
      GBP_C; Guanylate-binding protein, C-terminal domain

    6. NM_001272351.1 → NP_001259280.1  uncharacterized protein Dmel_CG34417, isoform R [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259280.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGT0
      Conserved Domains (4) summary
      cd00014
      Location:5022 → 5125
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3857 → 3868
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3810 → 3882
      GBP_C; Guanylate-binding protein, C-terminal domain

    7. NM_001272352.1 → NP_001259281.1  uncharacterized protein Dmel_CG34417, isoform S [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259281.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PJ82
      Conserved Domains (2) summary
      cd00014
      Location:3392 → 3495
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein

    8. NM_001103423.3 → NP_001096893.1  uncharacterized protein Dmel_CG34417, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096893.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUZ8
      Conserved Domains (2) summary
      cd00014
      Location:3277 → 3380
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein

    9. NM_001103425.3 → NP_001096895.1  uncharacterized protein Dmel_CG34417, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096895.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUZ9
      Conserved Domains (1) summary
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein

    10. NM_001272355.1 → NP_001259284.1  uncharacterized protein Dmel_CG34417, isoform V [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259284.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PH82
      Conserved Domains (2) summary
      cd00014
      Location:3276 → 3379
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein

    11. NM_001103426.3 → NP_001096896.1  uncharacterized protein Dmel_CG34417, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV00
      Conserved Domains (3) summary
      pfam12510
      Location:3127 → 3176
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3857 → 3868
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3810 → 3882
      GBP_C; Guanylate-binding protein, C-terminal domain

    12. NM_001201620.2 → NP_001188549.1  uncharacterized protein Dmel_CG34417, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188549.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSA5
      Conserved Domains (3) summary
      pfam12510
      Location:3010 → 3059
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3740 → 3751
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3693 → 3765
      GBP_C; Guanylate-binding protein, C-terminal domain

    13. NM_001103422.2 → NP_001096892.1  uncharacterized protein Dmel_CG34417, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096892.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV02, Q3KN62
      Conserved Domains (1) summary
      PHA03307
      Location:479 → 750
      PHA03307; transcriptional regulator ICP4; Provisional

    14. NM_001298018.1 → NP_001284947.1  uncharacterized protein Dmel_CG34417, isoform X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284947.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JDY1
      Conserved Domains (3) summary
      pfam12510
      Location:3073 → 3122
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3803 → 3814
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3756 → 3828
      GBP_C; Guanylate-binding protein, C-terminal domain

    15. NM_001201619.3 → NP_001188548.1  uncharacterized protein Dmel_CG34417, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188548.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MS17
      Conserved Domains (2) summary
      cd00014
      Location:3223 → 3326
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:3073 → 3122
      Smoothelin; Smoothelin cytoskeleton protein

    16. NM_001272347.1 → NP_001259276.1  uncharacterized protein Dmel_CG34417, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259276.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PJ79
      Conserved Domains (2) summary
      cd00014
      Location:1720 → 1823
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:1570 → 1619
      Smoothelin; Smoothelin cytoskeleton protein

    17. NM_001298019.1 → NP_001284948.1  uncharacterized protein Dmel_CG34417, isoform Y [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284948.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JEC4
      Conserved Domains (2) summary
      cd00014
      Location:3106 → 3209
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:2956 → 3005
      Smoothelin; Smoothelin cytoskeleton protein

    18. NM_001272348.1 → NP_001259277.1  uncharacterized protein Dmel_CG34417, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259277.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PDW3
      Conserved Domains (2) summary
      cd00014
      Location:1603 → 1706
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:1453 → 1502
      Smoothelin; Smoothelin cytoskeleton protein

    19. NM_001272349.1 → NP_001259278.1  uncharacterized protein Dmel_CG34417, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGI5
      Conserved Domains (2) summary
      cd00014
      Location:891 → 994
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:741 → 790
      Smoothelin; Smoothelin cytoskeleton protein

    20. NM_001298017.1 → NP_001284946.1  uncharacterized protein Dmel_CG34417, isoform W [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284946.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JIN0
      Conserved Domains (3) summary
      pfam12510
      Location:2956 → 3005
      Smoothelin; Smoothelin cytoskeleton protein
      cd16269
      Location:3686 → 3697
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:3639 → 3711
      GBP_C; Guanylate-binding protein, C-terminal domain

    21. NM_206636.2 → NP_996359.2  uncharacterized protein Dmel_CG34417, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996359.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      R9PY45
      Conserved Domains (1) summary
      cd00014
      Location:105 → 208
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JUZ8 A8JUZ8
    A8JUZ9 A8JUZ9
    A8JV00 A8JV00
    A8JV02 A8JV02
    E2QD99 E2QD99
    M9MS17 M9MS17
    M9MSA5 M9MSA5
    M9PDW3 M9PDW3
    M9PDW8 M9PDW8
    M9PGI5 M9PGI5
    M9PGT0 M9PGT0
    M9PH75 M9PH75
    M9PH82 M9PH82
    M9PJ79 M9PJ79
    M9PJ82 M9PJ82
    Q95TC5 Q95TC5
    Q961G7 Q961G7
    R9PY45 R9PY45
    X2JDY1 X2JDY1
    X2JEC4 X2JEC4
    X2JIN0 X2JIN0

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