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    T23G7.3 G-patch domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174456, updated on 9-Dec-2024

    Summary

    Official Symbol
    T23G7.3
    Official Full Name
    G-patch domain-containing protein
    Primary source
    WormBase:WBGene00011966
    Locus tag
    CELE_T23G7.3
    See related
    AllianceGenome:WB:WBGene00011966
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable telomerase inhibitor activity. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See T23G7.3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (9165929..9167830, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Acyltransferase 3 domain-containing protein Neighboring gene Regulator of hypoxia-inducible factor 1 Neighboring gene DapB_N domain-containing protein Neighboring gene Calcineurin-like phosphoesterase domain-containing protein Neighboring gene Transcription factor dpl-1 Neighboring gene Exocyst complex component 2

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleic acid binding  
    enables telomerase inhibitor activity  
    Component Evidence Code Pubs
    is_active_in nucleolus  

    General protein information

    Preferred Names
    G-patch domain-containing protein
    NP_495955.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9165929..9167830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063554.7NP_495955.1  G-patch domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495955.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22705
      Conserved Domains (1) summary
      smart00443
      Location:2469
      G_patch; glycine rich nucleic binding domain
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