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    B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 [ Mus musculus (house mouse) ]

    Gene ID: 14422, updated on 9-Dec-2024

    Summary

    Official Symbol
    B4galnt2provided by MGI
    Official Full Name
    beta-1,4-N-acetyl-galactosaminyl transferase 2provided by MGI
    Primary source
    MGI:MGI:1342058
    See related
    Ensembl:ENSMUSG00000013418 AllianceGenome:MGI:1342058
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dlb1; Ggm3; Dlb-1; Galg2; Galgt2; Igf2bp1
    Summary
    Predicted to enable acetylgalactosaminyltransferase activity. Acts upstream of or within several processes, including UDP-N-acetylglucosamine metabolic process; protein import; and skeletal muscle fiber differentiation. Predicted to be located in Golgi membrane. Is expressed in bladder fundus; hindgut; and midgut. Orthologous to human B4GALNT2 (beta-1,4-N-acetyl-galactosaminyltransferase 2 (SID blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in large intestine adult (RPKM 61.1), colon adult (RPKM 27.1) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See B4galnt2 in Genome Data Viewer
    Location:
    11 D; 11 59.02 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (95754385..95805786, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (95863559..95914960, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4833417C18 gene Neighboring gene STARR-positive B cell enhancer ABC_E305 Neighboring gene predicted gene, 38959 Neighboring gene nuclear encoded tRNA glutamine 6 (anticodon TTG) Neighboring gene predicted gene, 24725 Neighboring gene STARR-seq mESC enhancer starr_30524 Neighboring gene insulin-like growth factor 2 mRNA binding protein 1 Neighboring gene microRNA 3063

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acetylgalactosaminyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetylgalactosaminyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    beta-1,4 N-acetylgalactosaminyltransferase 2
    Names
    CT-Gal NAc transferase
    N-acetylgalactosaminyltransferase
    UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosyl-N-acetylglucosaminylpolypeptide-beta-1, 4-N-acetylgalactosaminyltransferase
    dolichos lectin binding 1
    NP_032107.1
    XP_006532264.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008081.3NP_032107.1  beta-1,4 N-acetylgalactosaminyltransferase 2

      Status: VALIDATED

      Source sequence(s)
      AL593858, AL606704
      Consensus CDS
      CCDS25285.1
      UniProtKB/Swiss-Prot
      Q09199
      UniProtKB/TrEMBL
      A2A615, F8VBU4, F8VBU5
      Related
      ENSMUSP00000037239.7, ENSMUST00000038343.7
      Conserved Domains (2) summary
      COG0463
      Location:266367
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      pfam00535
      Location:268412
      Glycos_transf_2; Glycosyl transferase family 2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      95754385..95805786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532201.4XP_006532264.1  beta-1,4 N-acetylgalactosaminyltransferase 2 isoform X1

      UniProtKB/TrEMBL
      F8VBU5
      Conserved Domains (1) summary
      pfam00535
      Location:268420
      Glycos_transf_2; Glycosyl transferase family 2