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    ATPsynbeta ATP synthase, beta subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43829, updated on 17-Dec-2024

    Summary

    Official Symbol
    ATPsynbetaprovided by FlyBase
    Official Full Name
    ATP synthase, beta subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010217
    Locus tag
    Dmel_CG11154
    See related
    AllianceGenome:FB:FBgn0010217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ATP; ATP syn-beta; ATP-B; ATP-syn-B; ATP-syn-beta; ATP-synbeta; ATP5B; ATP5beta; ATP5F1B; ATPase beta; ATPase-beta; ATPasebeta; ATPB; ATPsyn; ATPsyn b; ATPsyn-b; ATPsyn-beta; beta-ATPase; CG11154; Comp V beta; complex Vbeta; dATP5B; Dmel\CG11154
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Is expressed in several structures, including adult brain cell body rind; adult head; adult heart; adult hemolymph; and adult optic lobe. Orthologous to human ATP5F1B (ATP synthase F1 subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ATPsynbeta in Genome Data Viewer
    Location:
    102F6-102F6; 4-0 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (1031484..1034917)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (1052110..1055543)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene Plexin A Neighboring gene antisense RNA:CR44031 Neighboring gene uncharacterized protein Neighboring gene Mitochondrial inner membrane protein MPV17 Neighboring gene Calcium/calmodulin-dependent protein kinase II Neighboring gene Zyxin Neighboring gene apolipophorin

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    located_in mitochondrion PubMed 
    part_of proton-transporting ATP synthase complex  
    part_of proton-transporting ATP synthase complex, catalytic core F(1)  
    part_of proton-transporting ATP synthase complex, catalytic core F(1)  
    part_of proton-transporting ATP synthase, catalytic core  

    General protein information

    Preferred Names
    ATP synthase, beta subunit
    Names
    ATP synthase
    ATP synthase beta
    ATP synthase beta chain
    ATP synthase beta subunit
    ATP synthase beta-subunit
    ATP synthase subunit beta
    ATP synthase subunit beta, mitochondrial
    ATP synthase subunits beta
    ATP synthase-beta
    ATPsynbeta-PA
    ATPsynbeta-PC
    ATPsynbeta-PD
    CG11154-PA
    CG11154-PC
    CG11154-PD
    F0/F1 ATP synthase beta
    F1ATP synthase
    H+-ATPase beta subunit
    beta-F1-ATPase
    complex V beta
    mitochondrial ATPsynbeta

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      1031484..1034917
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272152.1 → NP_001259081.1  ATP synthase, beta subunit, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259081.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L0MQ04
      Conserved Domains (4) summary
      PRK09280
      Location:44 → 507
      PRK09280; F0F1 ATP synthase subunit beta; Validated
      cd01133
      Location:114 → 393
      F1-ATPase_beta; F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a ...
      pfam00306
      Location:401 → 508
      ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
      pfam02874
      Location:46 → 112
      ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain
    2. NM_001297790.1 → NP_001284719.1  ATP synthase, beta subunit, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284719.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05825, Q9V494
      UniProtKB/TrEMBL
      X2JH42
      Conserved Domains (1) summary
      PRK09280
      Location:38 → 501
      PRK09280; F0F1 ATP synthase subunit beta; Validated
    3. NM_166808.3 → NP_726631.1  ATP synthase, beta subunit, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726631.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q05825, Q9V494
      UniProtKB/TrEMBL
      X2JH42
      Related
      FBpp0088250
      Conserved Domains (1) summary
      PRK09280
      Location:38 → 501
      PRK09280; F0F1 ATP synthase subunit beta; Validated
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