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    NASP nuclear autoantigenic sperm protein [ Bos taurus (domestic cattle) ]

    Gene ID: 512427, updated on 27-Dec-2024

    Summary

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    Official Symbol
    NASPprovided by VGNC
    Official Full Name
    nuclear autoantigenic sperm proteinprovided by VGNC
    Primary source
    VGNC:VGNC:31887
    See related
    BGD:BT13359; Ensembl:ENSBTAG00000015346
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NASP in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (100460372..100489151, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene GC-rich promoter binding protein 1 like 1 Neighboring gene coiled-coil domain containing 17 Neighboring gene aldo-keto reductase family 1 member A1 Neighboring gene large ribosomal subunit protein uL22-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Requirement for nuclear autoantigenic sperm protein mRNA expression in bovine preimplantation development. Nagatomo H, et al. Anim Sci J, 2016 Mar. PMID 26690724
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NASP mRNA expression is required for preimplantation development into the blastocyst stage in cattle.
      Title: Requirement for nuclear autoantigenic sperm protein mRNA expression in bovine preimplantation development.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134231

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication-dependent chromatin assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear autoantigenic sperm protein
    Names
    nuclear autoantigenic sperm protein (histone-binding)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038088.3 → NP_001033177.2  nuclear autoantigenic sperm protein

      Status: PROVISIONAL

      Source sequence(s)
      BC111329
      UniProtKB/Swiss-Prot
      Q2T9P4
      UniProtKB/TrEMBL
      A0A3Q1M1D3
      Conserved Domains (4) summary
      sd00006
      Location:507 → 530
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:573 → 602
      TPR_1; Tetratricopeptide repeat
      pfam10516
      Location:531 → 568
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:528 → 605
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      100460372..100489151 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010803604.4 → XP_010801906.1  nuclear autoantigenic sperm protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M1D3, A0A3Q1M5Q7
      Related
      ENSBTAP00000065266.2, ENSBTAT00000068707.2
      Conserved Domains (4) summary
      sd00006
      Location:507 → 530
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:573 → 602
      TPR_1; Tetratricopeptide repeat
      pfam10516
      Location:531 → 568
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:528 → 605
      TPR_12; Tetratricopeptide repeat

    2. XM_059883558.1 → XP_059739541.1  nuclear autoantigenic sperm protein isoform X1

      UniProtKB/Swiss-Prot
      Q2T9P4
      UniProtKB/TrEMBL
      A0A3Q1M1D3

    3. XM_010803605.4 → XP_010801907.1  nuclear autoantigenic sperm protein isoform X3

      UniProtKB/TrEMBL
      A0AAA9TXM6, A5D969
      Related
      ENSBTAP00000048905.4, ENSBTAT00000057267.4
      Conserved Domains (3) summary
      sd00006
      Location:180 → 203
      TPR; TPR repeat [structural motif]
      pfam10516
      Location:204 → 241
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:202 → 278
      TPR_12; Tetratricopeptide repeat

    4. XM_010803603.4 → XP_010801905.1  nuclear autoantigenic sperm protein isoform X1

      UniProtKB/Swiss-Prot
      Q2T9P4
      UniProtKB/TrEMBL
      A0A3Q1M1D3
      Related
      ENSBTAP00000063517.2, ENSBTAT00000078061.2
      Conserved Domains (4) summary
      sd00006
      Location:507 → 530
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:573 → 602
      TPR_1; Tetratricopeptide repeat
      pfam10516
      Location:531 → 568
      SHNi-TPR; SHNi-TPR
      pfam13424
      Location:528 → 605
      TPR_12; Tetratricopeptide repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2T9P4.2 GenPept UniProtKB/Swiss-Prot:Q2T9P4

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