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    PRP40C pre-mRNA-processing protein 40C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821521, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRP40C
    Official Full Name
    pre-mRNA-processing protein 40C
    Primary source
    TAIR:AT3G19840
    Locus tag
    AT3G19840
    See related
    Araport:AT3G19840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPRP40C; pre-mRNA-processing protein 40C
    Summary
    Binds the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II and functions as a scaffold for RNA processing machineries.
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    Genomic context

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    See PRP40C in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Sequence:
    Chromosome: 3; NC_003074.8 (6890988..6897510)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene BTB/POZ domain protein, putative (DUF177) Neighboring gene cell elongation protein / DWARF1 / DIMINUTO (DIM) Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene ncRNA Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana PRP40s are RNA polymerase II C-terminal domain-associating proteins. Kang CH, et al. Arch Biochem Biophys, 2009 Apr 1. PMID 19467629
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112874.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pre-mRNA-processing protein 40C
    NP_188618.3
    • pre-mRNA-processing protein 40C (PRP40C); CONTAINS InterPro DOMAIN/s: FF domain (InterPro:IPR002713), WW/Rsp5/WWP (InterPro:IPR001202); BEST Arabidopsis thaliana protein match is: pre-mRNA-processing protein 40A (TAIR:AT1G44910.2); Has 7513 Blast hits to 5748 proteins in 436 species: Archae - 33; Bacteria - 336; Metazoa - 3654; Fungi - 967; Plants - 481; Viruses - 7; Other Eukaryotes - 2035 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6890988..6897510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112874.4 → NP_188618.3  pre-mRNA-processing protein 40C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188618.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GZ66, Q9LT25
      UniProtKB/TrEMBL
      A0A5S9XDS4
      Conserved Domains (5) summary
      COG5104
      Location:249 → 625
      PRP40; Splicing factor [RNA processing and modification]
      cd00201
      Location:299 → 328
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:249 → 274
      WW; WW domain
      pfam01846
      Location:457 → 506
      FF; FF domain
      pfam08347
      Location:103 → 201
      CTNNB1_binding; N-terminal CTNNB1 binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LT25.1

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