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CG15177 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40810, updated on 9-Dec-2024

Summary

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Official Symbol
CG15177provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037461
Locus tag
Dmel_CG15177
See related
AllianceGenome:FB:FBgn0037461
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15177
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human CLXN (calaxin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG15177 in Genome Data Viewer
Location:
84A1-84A1; 3-48 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6628204..6629321, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2453926..2455043, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene globin 2 Neighboring gene solwind Neighboring gene sungrazer Neighboring gene uncharacterized protein Neighboring gene Argininosuccinate synthase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The RNA export factor, Nxt1, is required for tissue specific transcriptional regulation. Caporilli S, et al. PLoS Genet, 2013 Jun. PMID 23754955, Free PMC Article
  2. Post-meiotic transcription in Drosophila testes. Barreau C, et al. Development, 2008 Jun. PMID 18434411
  3. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
  4. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15177-PA
CG15177-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6628204..6629321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275394.1 → NP_001262323.1  uncharacterized protein Dmel_CG15177, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262323.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KGA9
    Conserved Domains (2) summary
    pfam13499
    Location:115 → 172
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:116 → 171
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. NM_141415.2 → NP_649672.1  uncharacterized protein Dmel_CG15177, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649672.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VI39
    Related
    FBpp0081198
    Conserved Domains (2) summary
    pfam13499
    Location:115 → 180
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:116 → 179
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KGA9 A0A0B4KGA9
Q9VI39 Q9VI39

Gene LinkOut

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