U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp709 zinc finger protein 709 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266773, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Zfp709provided by RGD
Official Full Name
zinc finger protein 709provided by RGD
Primary source
RGD:628698
See related
EnsemblRapid:ENSRNOG00000016186 AllianceGenome:RGD:628698
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hit40; Znf14
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF443 (zinc finger protein 443). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 83.0), Muscle (RPKM 38.7) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zfp709 in Genome Data Viewer
Location:
16p14
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (17942986..17953720, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (17907599..17920047, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (19632954..19643956, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 617 Neighboring gene uncharacterized LOC102548752 Neighboring gene uncharacterized LOC134482464 Neighboring gene zinc finger protein 878 Neighboring gene HAUS augmin-like complex, subunit 8 Neighboring gene myosin IXb

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Heat stress modulates hepatocyte membrane proteins during endotoxemia. Przkora R, et al. Burns, 2007 Aug. PMID 17374454
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 14
Names
zinc finger protein 14 (KOX 6)
zinc finger protein HIT-40

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153731.1 → NP_714953.1  zinc finger protein 14

    See identical proteins and their annotated locations for NP_714953.1

    Status: PROVISIONAL

    Source sequence(s)
    AF277903
    UniProtKB/TrEMBL
    Q99PJ6
    Related
    ENSRNOP00000075334.3, ENSRNOT00000087597.3
    Conserved Domains (5) summary
    smart00349
    Location:11 → 51
    KRAB; krueppel associated box
    COG5048
    Location:259 → 701
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:431 → 451
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:11 → 50
    KRAB; KRAB box
    pfam13465
    Location:303 → 328
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    17942986..17953720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006252841.5 → XP_006252903.1  zinc finger protein 14 isoform X2

    See identical proteins and their annotated locations for XP_006252903.1

    UniProtKB/TrEMBL
    A0A0G2KAB4
    Conserved Domains (5) summary
    smart00349
    Location:25 → 65
    KRAB; krueppel associated box
    COG5048
    Location:273 → 715
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:445 → 465
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:25 → 64
    KRAB; KRAB box
    pfam13465
    Location:317 → 342
    zf-H2C2_2; Zinc-finger double domain

  2. XM_006252840.5 → XP_006252902.1  zinc finger protein 14 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AHX4
    Conserved Domains (5) summary
    smart00349
    Location:40 → 80
    KRAB; krueppel associated box
    COG5048
    Location:288 → 730
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460 → 480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:40 → 79
    KRAB; KRAB box
    pfam13465
    Location:332 → 357
    zf-H2C2_2; Zinc-finger double domain

  3. XM_039094244.2 → XP_038950172.1  zinc finger protein 14 isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:220 → 662
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392 → 412
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_008771070.4 → XP_008769292.1  zinc finger protein 14 isoform X3

    See identical proteins and their annotated locations for XP_008769292.1

    Conserved Domains (2) summary
    COG5048
    Location:220 → 662
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392 → 412
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_008771069.4 → XP_008769291.1  zinc finger protein 14 isoform X3

    See identical proteins and their annotated locations for XP_008769291.1

    Conserved Domains (2) summary
    COG5048
    Location:220 → 662
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:392 → 412
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_008771072.4 → XP_008769294.1  zinc finger protein 14 isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:141 → 583
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:313 → 333
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:185 → 210
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools