GEO DataSet Links for PMC (Select 9308330) - GEO DataSets

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Items: 2

Select item 2001640811.

Alternative transcription start sites contribute to acute-stress–induced transcriptome response in human skeletal muscle

(Submitter supplied) More than half of human protein-coding genes have an alternative transcription start site (TSS). We aimed to investigate the contribution of alternative TSSs to the acute-stress–induced transcriptome response in human tissue (skeletal muscle) using the cap analysis of gene expression approach. TSSs were examined at baseline and during recovery after acute stress (a cycling exercise). We identified 44,680 CAGE TSS clusters (including 3,764 first defined) belonging to 12,268 genes and annotated for the first time 290 TSSs belonging to 163 genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL18573 GPL11154 GPL16791
50 Samples

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Accession:: GSE164081

ID:: 200164081

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001208622.

Contractile activity-specific transcriptome response to acute endurance exercise and training in human skeletal muscle

(Submitter supplied) In our study, we investigated for contractile activity-specific changes in the transcriptome in untrained and trained (after an aerobic training programme) human skeletal muscle. The second goal was to examine effect of aerobic training on gene expression in muscle at baseline (after long term training). Seven untrained males performed the one-legged knee extension exercise (for 60 min) with the same relative intensity before and after a 2 month aerobic training programme (1 h/day, 5/week). more...