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Links from GEO DataSets

Items: 20

1.

Single cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate

(Submitter supplied) Evaluating the complex interplay of cell types in the tissue microenvironment is critical to understanding the origin and progression of diseases in the prostate and potential opportunities for intervention. Mouse models are an essential tool to investigate the molecular and cell-type-specific contributions of prostate disease at an organismal level. While there are well-documented differences in the extent, timing, and nature of disease development in various genetically engineered and exposure-based mouse models in different mouse strains and prostate lobes within each mouse strain, the underlying molecular phenotypic differences in cell types across mouse strains and prostate lobes are incompletely understood.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
20 Samples
Download data: MTX, TSV
Series
Accession:
GSE165741
ID:
200165741
2.

Single-cell RNA-sequencing of adult mouse lower urinary tracts v2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL24247
7 Samples
Download data: H5
Series
Accession:
GSE173096
ID:
200173096
3.

Single-cell RNA-sequencing of adult mouse urethra v2

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse urethra on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL19057
3 Samples
Download data: H5
Series
Accession:
GSE172515
ID:
200172515
4.

Single-cell RNA-sequencing of adult human normal and BPH (glandular and stroma) prostates and urethra

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL18573
19 Samples
Download data: H5
Series
Accession:
GSE172357
ID:
200172357
5.

Single-cell RNA-sequencing of adult mouse prostates v2

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse prostates on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
4 Samples
Download data: H5
Series
Accession:
GSE172352
ID:
200172352
6.

Bulk RNA-sequencing of fibroblasts isolated by FACS from normal human prostate

(Submitter supplied) Differential expression of prostatic fibroblasts were determined using RNA-sequencing of FACS sorted fibroblasts from normal human prostate transition and peripheral.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
9 Samples
Download data: TXT
Series
Accession:
GSE172347
ID:
200172347
7.

Single-cell RNA-sequencing of adult human prostates from organ donors v2

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates FACS sorted for viability from organ donors (with no known prostatic diseases) on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: H5
Series
Accession:
GSE172316
ID:
200172316
8.

Single-cell RNA-sequencing of adult human prostates from BPH patients (glandular and stromal phenothpes)

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates from BPH patients on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL18573
13 Samples
Download data: H5
Series
Accession:
GSE172301
ID:
200172301
9.

Single-cell RNA-sequencing of adult mouse lower urinary tracts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
6 Samples
Download data: H5
Series
Accession:
GSE145929
ID:
200145929
10.

Single-cell RNA-sequencing of adult human prostates and urethra (normal and diseased)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
9 Samples
Download data: H5
Series
Accession:
GSE145928
ID:
200145928
11.

Single-cell RNA-sequencing of adult mouse urethra

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse urethra on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: H5
Series
Accession:
GSE145865
ID:
200145865
12.

Single-cell RNA-sequencing of adult mouse prostates

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse prostates on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
4 Samples
Download data: H5
Series
Accession:
GSE145861
ID:
200145861
13.

Single-cell RNA-sequencing of adult human prostates from organ donors

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates FACS sorted for viability from organ donors (with no known prostatic diseases) on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: H5
Series
Accession:
GSE145843
ID:
200145843
14.

Single-cell RNA-sequencing of adult human prostates from BPH patients

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates FACS sorted for viability from BPH patients on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
3 Samples
Download data: H5
Series
Accession:
GSE145838
ID:
200145838
15.

Single-cell RNA-seq analysis of mouse and human prostate

(Submitter supplied) Single-cell RNA-seq analysis of wild-type mouse and benign human prostate
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL24676
9 Samples
Download data: TXT
Series
Accession:
GSE150692
ID:
200150692
16.

Comparative transcriptome analysis of metastatic heterogeneity in a mouse model of breast cancer

(Submitter supplied) We aimed to understand the transcriptome patterns of organ-derived cancer cell isolates from MMTV-PyMT mice. Tissues from primary tumors and organs harboring distal metastases were harvested from cancer bearing female mice. Although metastatic progression from primary tumors to lung tissue is well studied in the MMTV-PyMT model, metastases to other distal organs and the significance of intratumor heterogeneity across metastases from distal organs remain unclear. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
17 Samples
Download data: CSV
Series
Accession:
GSE165393
ID:
200165393
17.

RNA-seq analysis of FACS-isolated distinct cell lineages in adult mouse prostates

(Submitter supplied) To further characterize the molecular and biological features of the Sca-1+ luminal cells, we performed an RNA-seq analysis using FACS-isolated distinct cell lineages in adult mouse prostates, including the Lin-CD24lowCD49fhigh basal cells, Lin-CD24-CD49f- stromal cells, Lin-CD24highCD49flowSca-1- luminal cells, and Lin-CD24highCD49flowSca-1+ luminal cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9185
10 Samples
Download data: TXT
Series
Accession:
GSE144602
ID:
200144602
18.

scRNA-Seq analysis of Trim28-deleted NPp53 mouse prostate tissue

(Submitter supplied) The Tripartite motif-containing 28 (TRIM28) transcription factor is upregulated in high-grade prostate cancers and was recently proposed as a therapeutic target for castration-resistant prostate cancers. To study the role of TRIM28 in prostate cancer progression in vivo, we used a genetically engineered mouse model, combining prostate-specific Trim28 inactivation with inactivation of Trp53 and Pten. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: H5
Series
Accession:
GSE199015
ID:
200199015
19.

A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cell

(Submitter supplied) To study the development and composition of human ocular surface, we performed single cell (sc) RNA-Seq at key embryonic, fetal and adult stages and generated the first atlas of the corneal and conjunctival cell types from development to adulthood. The conjunctival epithelium is the first to be specified in the epithelial layer , followed by the corneal epithelium and the establishment of proliferative epithelial progenitors, which predate the formation of limbal niche by a few weeks. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
32 Samples
Download data: CSV, TXT
Series
Accession:
GSE155683
ID:
200155683
20.

Exploratory Single Cell RNA Sequencing: Murine Ciliary Body Transcriptome

(Submitter supplied) Single cell RNA-seq was performed on dissected murine ciliary body samples, and the resulted sequencing data was used to assess the various cell types present within the dissected tissue
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
2 Samples
Download data: MTX, TSV
Series
Accession:
GSE178667
ID:
200178667
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Supplemental Content

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