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Links from GEO DataSets

Items: 20

1.

mRNA expression in parotid acinar cells during terminal differentiation

(Submitter supplied) Terminal differentiation in parotid acini relies on sustained changes in gene expression during the first few postnatal weeks. Little is known about what drives these changes. Expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation. We used expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL1355
27 Samples
Download data: CEL
Series
Accession:
GSE65586
ID:
200065586
2.

Expression in parotid acinar cells during terminal differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Rattus norvegicus
Type:
Expression profiling by array; Other
Platforms:
GPL19707 GPL1355
39 Samples
Download data: CEL
Series
Accession:
GSE65587
ID:
200065587
3.

microRNA expression in parotid acinar cells during terminal differentiation

(Submitter supplied) Terminal differentiation in parotid acini relies on sustained changes in gene expression during the first few postnatal weeks. Little is known about what drives these changes. Expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation. We used both microRNA and mRNA expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation.
Organism:
Mus musculus; Rattus norvegicus
Type:
Other
Platform:
GPL19707
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE65324
ID:
200065324
4.

Expression of Wigglesworthia glossinidia endosymbiont of Glossina morsitans morsitans genes

(Submitter supplied) Transcriptome analysis of Wigglesworthia glossinidia endosymbiont derived from uninfected and infected samples at 3 time points (3, 10 and 20 days). Expression profiling by array - Wigglesworthia glossinidia endosymbiont of Glossina morsitans morsitans
Organism:
Wigglesworthia glossinidia endosymbiont of Glossina morsitans
Type:
Expression profiling by array
Platform:
GPL18427
24 Samples
Download data: TXT
Series
Accession:
GSE55931
ID:
200055931
5.

Expression of Sodalis glossinidius genes derived from self-cleared and infected Glossina palpalis gambiensis flies

(Submitter supplied) Transcriptome analysis of Sodalis glossinidius derived from Trypanosoma brucei gambiense infection self cleared and infected Glossina palpalis gambiensis. At 3 time points (3, 10 and 20 days) after infectived blood meal, flies were analysed by PCR to isolate the infected and infection self cleared flies. Then, infected and infection self cleared flies midgut were dissected for RNA extraction.
Organism:
Sodalis glossinidius
Type:
Expression profiling by array
Platform:
GPL17347
24 Samples
Download data: TXT
Series
Accession:
GSE48361
ID:
200048361
6.

Expression of Sodalis glossinidius genes derived from self-cleared and control Glossina palpalis gambiensis flies

(Submitter supplied) Transcriptome analysis of Sodalis glossinidius derived from uninfected (controls) and Trypanosoma brucei gambiense infection self cleared Glossina palpalis gambiensis. 10 days after infectived blood meal, flies anal drop were analysed by PCR to isolate the infected self cleared flies. Then, uninfected (controls) and infection self cleared 10 days-flies midgut were dissected for RNA extraction.
Organism:
Sodalis glossinidius
Type:
Expression profiling by array
Platform:
GPL17347
8 Samples
Download data: TXT
Series
Accession:
GSE48360
ID:
200048360
7.

Comparison of gene expression data between undifferentiated hES cells and MSC-derived hES cells

(Submitter supplied) Analysis of genes that were differentially expressed in MSC-derived hES cells (VUB01 and SA01) as compared to VUB01 and SA01 undifferentiated hES cells Keywords: differentiation state analysis
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE7879
ID:
200007879
8.

The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells

(Submitter supplied) Antibody secretion by plasma cells provides acute and long-term protection against pathogens. The high secretion potential of plasma cells depends on the unfolded protein response, which is controlled by the transcription factor Xbp1. Here, we analyzed the Xbp1-dependent gene expression program of plasma cells and identified Bhlha15 (Mist1) as the most strongly activated Xbp1 target gene. As Mist1 plays an important role in other secretory cell types, we analyzed in detail the phenotype of Mist1-deficient plasma cells in Cd23-Cre Bhlha15(fl/fl) mice under steady-state condition or upon NP-KLH immunization. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
13 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE190591
ID:
200190591
9.

miRNA-transcriptome expression pattern during differentiation in human skeletal muscle cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL11532 GPL15829
44 Samples
Download data: CEL, TXT
Series
Accession:
GSE53384
ID:
200053384
10.

Dynamic time course miRNA profiling of human skeletal muscle cell differentiation.

(Submitter supplied) The purpose of this study was to determine the miRNA expression profile of in vitro differentiation of human skeletal muscle cells and to couple changes in individual miRNA expression to transcriptional output of target genes. miRNA expression profiling at six different time points during the in vitro differentiation process of human skeletal muscle cells from six subjects. RNA was harvested from myoblasts before induction of differentiation and at every other day for 10 following days.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL15829
35 Samples
Download data: TXT
Series
Accession:
GSE53383
ID:
200053383
11.

Dynamic time course mRNA profiling of human skeletal muscle cell differentiation.

(Submitter supplied) The purpose of this study was to determine the miRNA expression profile of in vitro differentiation of human skeletal muscle cells and to couple changes in individual miRNA expression to effects on target genes by transcriptome profiling of mRNA expression. mRNA expression profiling at three different time points during the in vitro differentiation process of human skeletal muscle cells from three subjects. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL11532
9 Samples
Download data: CEL
Series
Accession:
GSE53382
ID:
200053382
12.

Comprehensive mapping of transcriptional networks specifying lactogenic differentiation of murine mammary epithelial stem like cells

(Submitter supplied) Purpose: Understanding of gene transcriptional networks specifying murine mammary epithelial cells (HC11) during lactogenic differentiation and its comparision with murine embryonic stem cells Methods: RNA-sequencing after ribosomal RNA depletion followed by cDNA synthesis, adaptor ligation and sequencing in duplicate of each sample using Illumina Hi-seq 2500 paired end sequencing. Sequence reads with adapters, over-represented and low-quality reads were discarded. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
8 Samples
Download data: XLSX
Series
Accession:
GSE107419
ID:
200107419
13.

Nos3-/- iPSCs model concordant signatures of in utero cardiac pathogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
43 Samples
Download data: CEL
Series
Accession:
GSE69317
ID:
200069317
14.

Nos3-/- iPSCs model concordant signatures of in utero cardiac pathogenesis [iPSCs]

(Submitter supplied) Through genome-wide transcriptional comparisons, this study interrogates the capacity of iPSCs to accurately model pathogenic signatures of structural cardiac defects. Herein, we studied the molecular etiology of structural cardiac defects in Nos3-/- mice via transcriptional analysis of stage-matched embryonic and iPSC-derived tissues. In vitro comparisons of differentiated embryoid bodies were calibrated to in utero benchmarks of health and disease. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
31 Samples
Download data: CEL
Series
Accession:
GSE69316
ID:
200069316
15.

Nos3-/- iPSCs model concordant signatures of in utero cardiac pathogenesis [tissue]

(Submitter supplied) Through genome-wide transcriptional comparisons, this study interrogates the capacity of iPSCs to accurately model pathogenic signatures of structural cardiac defects. Herein, we studied the molecular etiology of structural cardiac defects in Nos3-/- mice via transcriptional analysis of stage-matched embryonic and iPSC-derived tissues. In vitro comparisons of differentiated embryoid bodies were calibrated to in utero benchmarks of health and disease. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE69315
ID:
200069315
16.

Transcriptomic and Single Cell Analysis of the Murine Parotid Gland

(Submitter supplied) By combining bulk RNA-seq and scRNA-seq approaches we have generated a comprehensive transcriptomic map of the murine parotid gland at different stages of maturation.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
1 Sample
Download data: TXT
Series
Accession:
GSE132867
ID:
200132867
17.

Functional characterization of the Differences Between Parotid and Submandibular Salivary Glands

(Submitter supplied) We applied both single cell and bulk RNA-sequencing to characterize and identify uniqueness in gene expression of the mouse Parotid gland compared to other tissues including the submandibular gland
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16417
7 Samples
Download data: XLSX
Series
Accession:
GSE131285
ID:
200131285
18.

MiRNA expression profiles of trophoblastic cells

(Submitter supplied) To gain more insight in the biological expression and role of microRNAs in trophoblast cells, we then set up to determinate the miRNA expression pattern of four trophoblastic cell lines and compare them with the miRNA signature of isolated trophoblast Total RNA was reverse-transcribed, pre-amplified with miRNA-specific primers, and loaded into TLDA cards. Quantitative real-time PCR was performed for 768 miRNAs. more...
Organism:
Homo sapiens
Type:
Expression profiling by RT-PCR
Platform:
GPL15497
15 Samples
Download data: TXT
Series
Accession:
GSE32346
ID:
200032346
19.

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

(Submitter supplied) Immune checkpoint blockade (ICB) therapy provides remarkable clinical gains, where melanoma is at the forefront of its success. However, only a subset of patients with advanced tumors currently benefit from these therapies, which at times incur considerable side-effects and costs. Constructing such predictors of patient’s response has remained a serious challenge due to the complexity of the immune response and the shortage of large ICB-treated patient cohorts including both omics and response data. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
37 Samples
Download data: CSV
20.

Expression data from budding yeast exposed to simulated asbestos mine drainage

(Submitter supplied) Investigation of global gene expression changes in Saccharomyces cerevisiae strain NRRL Y-12632 (ATCC® 18824) grown in media made with asbestos mine tailings-laden water compared to the control grown in media made with double distilled water
Organism:
Schizosaccharomyces pombe; Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL2529
7 Samples
Download data: CEL
Series
Accession:
GSE89875
ID:
200089875
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