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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 27, 2015 |
| Title |
microRNA expression in parotid acinar cells during terminal differentiation |
| Platform organisms |
Mus musculus; Rattus norvegicus |
| Sample organism |
Rattus norvegicus |
| Experiment type |
Other
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| Summary |
Terminal differentiation in parotid acini relies on sustained changes in gene expression during the first few postnatal weeks. Little is known about what drives these changes. Expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation.
We used both microRNA and mRNA expression measurements along with knowledgebased network analysis was used to develop a prospective gene regulatory network that drives differentiation.
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| Overall design |
laser capture microdissection was used to isolate acinar cells from the parotid at four timepoints in triplicate (E20, P5, P15, and P25). RNA was isolated, and used to measure microRNA expression.
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| Citation(s) |
25928148, 26484231 |
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| Submission date |
Jan 26, 2015 |
| Last update date |
Oct 21, 2015 |
| Contact name |
Douglas Darling |
| E-mail(s) |
[email protected]
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| Organization name |
University of Louisville
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| Department |
Oral Immunology and Infectious Diseases
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| Street address |
501 S. Preston St.
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| City |
Louisville |
| State/province |
KY |
| ZIP/Postal code |
40202 |
| Country |
USA |
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| Platforms (1) |
| GPL19707 |
miRCURY LNA Universal RT microRNA PCR mouse and rat panel I, V1.M |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE65587 |
Expression in parotid acinar cells during terminal differentiation |
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| Relations |
| BioProject |
PRJNA273672 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE65324_LogFoldChange_miRNA.xlsx |
77.6 Kb |
(ftp)(http) |
XLSX |
| GSE65324_raw_CT_data.txt.gz |
16.5 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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