GEO DataSets

(Submitter supplied) Follicular dendritic cells (FDC) are important stromal cells within the B cell follicles and germinal centres (GC) of secondary lymphoid tissues. FDC trap and retain native antigens on their surfaces in the form of immune complexes which they display to B cells, in order to select those cells with the highest antigen affinity. MicroRNAs are short, non-coding RNAs of approximately 18-25 nucleotides in length that regulate gene expression at the post-transcriptional level by repressing the translation of target genes. more...

Organism:

Mus musculus; synthetic construct

Type:

Non-coding RNA profiling by array

Platform:

GPL14613

8 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus; synthetic construct

Type:

Non-coding RNA profiling by array

Platforms:

GPL18398 GPL14613

16 Samples

Download data: CEL, TXT

(Submitter supplied) Follicular dendritic cells (FDC) are important stromal cells within the B cell follicles and germinal centres (GC) of secondary lymphoid tissues. FDC trap and retain native antigens on their surfaces in the form of immune complexes which they display to B cells, in order to select those cells with the highest antigen affinity. MicroRNAs are short, non-coding RNAs of approximately 18-25 nucleotides in length that regulate gene expression at the post-transcriptional level by repressing the translation of target genes. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL18398

8 Samples

Download data: TXT

(Submitter supplied) treatment of mesenteric lymph nodes with soluble lymphotoxin-beta receptor for 0,1,2,3,27 and 35 days Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS2004 GDS2005

Platforms:

GPL340 GPL339

36 Samples

Download data: CEL

(Submitter supplied) Comparison of follicular dendritic cell-enriched versus -depleted splenocytes Keywords: parallel sample

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS1585 GDS1599 GDS1600

Platforms:

GPL81 GPL82 GPL83

14 Samples

Download data: CEL

Analysis of lymph nodes from animals treated with soluble lymphotoxin-beta receptor (LTbetaR)-immunoglobulin fusion protein (LTbetaR-Ig) for up to 35 days. LTbetaR-Ig inhibits LTbetaR activation, important in the differentiation of lymphoid germinal centers and follicular dendritic cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 6 time sets

Platform:

GPL340

Series:

GSE2124

18 Samples

Download data: CEL

Analysis of lymph nodes from animals treated with soluble lymphotoxin-beta receptor (LTbetaR)-immunoglobulin fusion protein (LTbetaR-Ig) for up to 35 days. LTbetaR-Ig inhibits LTbetaR activation, important in the differentiation of lymphoid germinal centers and follicular dendritic cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 6 time sets

Platform:

GPL339

Series:

GSE2124

18 Samples

Download data: CEL

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL83

Series:

GSE2123

5 Samples

Download data: CEL

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL82

Series:

GSE2123

4 Samples

Download data: CEL

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL81

Series:

GSE2123

5 Samples

Download data: CEL

(Submitter supplied) Upon immunization with a T cell dependent antigen naive follicular B cells (Fo) are activated and a germinal center reaction is induced. Within the next 2 weeks large germinal centers develop where the process of affinity maturation takes place. To analyze the gene expression profile of resting and activated B cells, follicular B cells (Fo), B cells from early (GC1) and late germinal centers (GC2) were isolated and their gene expression profile compared.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

6 Samples

Download data: CEL, CHP

(Submitter supplied) expression profiles of FDC and BMDC are compared Keywords: cell type comparison

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

6 Samples

Download data

(Submitter supplied) Cells from 2 FL patients and 1 FL cell line were cultured for up to 48h, with no stroma or on top of HK cells pre-establised layers. RNA from FL cells was isolated after 24 and 48h of culture The aim of this study was to uncover the molecular mechanisms underlying the FL-FDC crosstalk

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL13667

12 Samples

Download data: CEL

(Submitter supplied) By employing miRCURY LNA™ microRNA Array, we have identified a subset of 21 top miRNAs that are differentially expressed between GM-BMM and M-BMM cells

Organism:

Mus musculus; Human gammaherpesvirus 8; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human alphaherpesvirus 1; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Homo sapiens; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL11434

4 Samples

Download data: TXT

(Submitter supplied) Liver is uniquely capable to repair itself after injury. Multiple molecular and biochemical processes initiated after partial hepatectomy, lead to proliferation of all cells within the liver. MicroRNAs (miRNAs) are a class of highly abundant non-coding RNA molecules that cause post-transcriptional gene repression and are involved in several biological processes including cell cycle regulation and differentiation. more...

Organism:

Mus musculus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae; Rattus norvegicus; Murid gammaherpesvirus 4; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL7723

2 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Rattus norvegicus; Mus musculus; Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL18609 GPL18615

120 Samples

Download data: CEL, GPR, TXT

(Submitter supplied) The study investigated differential gene expression in primary mouse hepatocyte mRNA following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological replicates per compound/solvent.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL18615

60 Samples

Download data: CEL

(Submitter supplied) The study investigated differential miRNA changes in primary mouse hepatocyte following 24 and 48 hours of exposure to aflatoxin B1, cisplatin, benzo(a)pyrene, 2,3,7,8-tetrachloordibenzo-p-dioxine, cyclosporin A or Wy-14,643 or their responsive solvent. Three (four for Wy-14,643) biological replicates per compound/solvent.

Organism:

Rattus norvegicus; Mus musculus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL18609

60 Samples

Download data: GPR, TXT

(Submitter supplied) Mouse Embryonic Stem Cells (mESCs) were differentiated with EB formation and characterized with Flk1 and PDGFαR specific antibodies. miRNA profile of lateral mesodermal cells, paraxial mesodermal cells, DN (Double negative) and DP (Double positive) populations were firstly determined and effects of differentially expressed miRNAs transfected transiently on EB formation, and myogenic and hematopoietic differentiation potential were assessed.

Organism:

synthetic construct; Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL21572

12 Samples

Download data: CEL, CHP