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Links from GEO DataSets

Items: 1 to 20 of 34

1.
Full record GDS430

Stem cell self renewal and Bmi-1 (MG-U74C)

Molecular basis of renewal properties in Bmi-1-deficient central and peripheral nervous system stem cells. Bmi-1 is a polycomb transcriptional repressor. Forebrain and gut neurospheres cultured from postnatal day 0 Bmi-1 -/- and wild type mice compared.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type, 2 strain sets
Platform:
GPL83
Series:
GSE611
4 Samples
Download data
2.
Full record GDS4463

Endothelial cells from P8 neonatal retina [MG_U74Cv2]

Analysis of FACS-sorted, GFP-positive endothelial cells from retinas of postnatal day 8 (P8) homozygous Tie2-GFP transgenics. Deregulated retinal angiogenesis causes vision loss in many ocular diseases. Results provide insight into the molecular mechanisms underlying intraretinal angiogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type sets
Platform:
GPL83
Series:
GSE27238
6 Samples
Download data: CEL
3.
Full record GDS3446

Embryonic stem cell response to STAT3 overexpression in vitro (MG-U74C)

Analysis of cultured embryonic stem (ES) cells overexpressing the transcription factor STAT3. STAT3 is a downstream target of the LIF signaling cascade. LIF activation maintains ES cells in a pluripotent state. Results provide insight into the role of STAT3 in maintenance of ES cell pluripotency.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL83
Series:
GSE11398
6 Samples
Download data: CEL, CHP
4.
Full record GDS3382

Visual cortex during the critical period for ocular dominance (MG-U74C)

Analysis of visual cortices before the critical period for ocular dominance plasticity opens [postnatal day 14 (P14)], at the peak sensitivity of the critical period (P28), and after the critical period (P60). Results provide insight into the molecular mechanisms associated with the critical period.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age sets
Platform:
GPL83
Series:
GSE11764
10 Samples
Download data: CEL, CHP
5.
Full record GDS3351

STAT5 depleted pro-B cell line response to IL-3: time course (MG-U74C)

Analysis of STAT5A and STAT5B depleted pro-B Ba/F3-beta cells stimulated with IL-3 for 0.5 or 2 hours. STAT5A and STAT5B are members of the family of signal transducers and activators of transcription. Results identify IL-3 inducible STAT5 target genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 protocol, 3 time sets
Platform:
GPL83
Series:
GSE10389
5 Samples
Download data: CEL, CHP
6.
Full record GDS2950

Pancreatic development (MG-U74C)

Analysis of pancreatic tissues from NMRI animals from embryonic day E12.5 to E16.5. Results provide insight into the molecular mechanisms underlying the development of the pancreas.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 5 age sets
Platform:
GPL83
Series:
GSE8070
10 Samples
Download data: CEL
DataSet
Accession:
GDS2950
ID:
2950
7.
Full record GDS2331

Acute myocardial infarction model: time course (MG-U74C)

Analysis of left heart ventricles (LV) at various time points up to 48 hours following surgically induced acute myocardial infarction (AMI). Ischemic/infarcted tissue, surviving free wall, and the interventricular septum of LV examined. Results provide insight into the molecular pathogenesis of AMI.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 disease state, 7 time, 4 tissue sets
Platform:
GPL83
Series:
GSE4648
66 Samples
Download data: CEL
DataSet
Accession:
GDS2331
ID:
2331
8.
Full record GDS2285

Uniparental duplication of chromosome 7 regions effect on various tissues (MG-U74C)

Analysis of various tissues from animals bearing maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps proximal and distal to the breakpoint. Results provide insight into the extent and distribution of imprinted genes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 genotype/variation, 4 tissue sets
Platform:
GPL83
Series:
GSE4870
11 Samples
Download data: CEL, EXP
9.
Full record GDS2186

Runt-related transcription factor 2 null mutation effect on the embryonal bone (MG-U74C)

Analysis of embryonic day 14.5 humeri of runt-related transcription factor 2 (Runx2) deficient animals. Runx2 is an essential factor for skeletogenesis and heterozygous loss causes cleidocranial dysplasia. Results provide insight into the molecular mechanisms underlying skeletogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL83
Series:
GSE4911
4 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2186
ID:
2186
10.
Full record GDS2179

Type 1 diabetes model: autoimmune target organs (MG-U74C)

Analysis of pancreata and submandibular and lacrimal glands from 6-, 9-, and 15-week-old NOD/scid animals, respectively, before the onset of autoimmune destruction of the tissues. The NOD/scid animal is a model for type 1 diabetes. The three organs examined are autoimmune targets in type 1 diabetes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 strain, 3 tissue sets
Platform:
GPL83
Series:
GSE4953
39 Samples
Download data
11.
Full record GDS2013

Lupus-prone BWF1 males and females: spleen (MG-U74C)

Analysis of spleens from 4-month-old pre-lupus male and female BWF1 animals. The BWF1 strain is a model for systemic lupus erythematosus. BWF1 females are more prone to lupus than BWF1 males.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 gender sets
Platform:
GPL83
Series:
GSE2336
8 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2013
ID:
2013
12.
Full record GDS1988

Airway disease trait manifestation in various genetic backgrounds: lungs (MG-U74C)

Analysis of lungs of animals exhibiting extremes in airway hyperreactivity, goblet cell metaplasia, or both. Animals were derived from an intercross of an F1 hybrid strain, generated by crossing C57Bl/6J and Balb/cJ strains. Results provide insight into the pathogenesis of complex airway diseases.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 disease state, 2 other sets
Platform:
GPL83
Series:
GSE3925
12 Samples
Download data
13.
Full record GDS1986

Primary visual cortex response to visual input deprivation (MG-U74C)

Analysis of primary visual cortex (V1) under conditions of binocular deprivation by dark-rearing (DR) or monocular deprivation (MD). Animals subjected to DR from birth till postnatal day (P) 27 or to MD from P11-12 to P27. Results provide insight into the role of visual activity in V1 development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 other, 3 protocol sets
Platform:
GPL83
Series:
GSE4537
12 Samples
Download data
DataSet
Accession:
GDS1986
ID:
1986
14.
Full record GDS1936

Positively selected H-2b T cell receptor transgenic thymocytes (MG-U74C)

Analysis of positively selected T cell receptor (TCR) transgenic thymocytes from H-2b animals. T lymphocyte development involves TCR-mediated positive selection that ensures the survival of potentially useful T cells. Results provide insight into T lymphocyte development and selection.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL83
Series:
GSE3909
4 Samples
Download data: CEL, EXP
15.
Full record GDS1880

Myotube response to PGC-1alpha induced mitochondrial biogenesis: time course (MG-U74C)

Analysis of C2C12 myoblast-derived myotubes transduced with transcriptional coactivator PGC-1alpha to induce mitochondrial proliferation in the muscle cells. Cells examined up to 3 days post-transduction. Results combined with other genome-scale datasets to identify mitochondrial proteins.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 agent, 4 time sets
Platform:
GPL83
Series:
GSE4330
21 Samples
Download data: CEL
DataSet
Accession:
GDS1880
ID:
1880
16.
Full record GDS1658

Dendritic cell subpopulations: spleen (MG-U74C)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL83
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1658
ID:
1658
17.
Full record GDS1633

Osteoblast differentiation (MG-U74C)

Analysis of FACS-sorted bone cells 7 and 17 days following induction of differentiation. Cells sorted based on GFP expression from a promoter that becomes active in the preosteoblastic stage between days 5 and 7 or from one that remains inactive until the osteoblastic stage between days 15 and 17.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 protocol, 2 time sets
Platform:
GPL83
Series:
GSE2332
13 Samples
Download data
DataSet
Accession:
GDS1633
ID:
1633
18.
Full record GDS1600

Follicular dendritic cell enriched splenocytes (MG U74C)

Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell type sets
Platform:
GPL83
Series:
GSE2123
5 Samples
Download data: CEL
DataSet
Accession:
GDS1600
ID:
1600
19.
Full record GDS1339

T cell anergy induction regulation by Egr-2 and Egr-3 (MG-U74C)

Analysis of pooled mRNA (2, 4, 6 hours) from A.E7 T cell clones activated in conditions that promote (anti-TCR) or inhibit (anti-TCR + CsA or PKCi or Combo) anergy induction. Results identify the early growth response gene 2 (Egr-2) and Egr-3 as key positive regulators of T cell anergy induction.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 5 agent, 3 protocol sets
Platform:
GPL83
Series:
GSE2323
5 Samples
Download data
DataSet
Accession:
GDS1339
ID:
1339
20.
Full record GDS837

Spermatogonia in Zfp145 knockout (MG-U74C)

Expression analysis of spermatogonia, mitotic germ cells of the testis, in 1 week old wild type or Zfp145 (Plzf) knockout. PLZF plays role in maintenance of spermatogonial stem cells.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL83
Series:
GSE1399
2 Samples
Download data
DataSet
Accession:
GDS837
ID:
837
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