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Items: 4

1.

Hominid-specific transposable elements and KRAB-ZFPs facilitate human embryonic genome activation and transcription in naïve hESCs [ChIP-seq]

(Submitter supplied) Transposable elements (TEs) are key to the evolutionary turnover of regulatory sequences. How they can play such an essential role in spite of their genotoxic potential is unknown. Here, we demonstrate that KRABcontaining zinc finger proteins control the timely and pleiotropic engagement of TE-derived cis-regulators of transcription. We first observed that evolutionary recent TEs of the SVA, HERVK and HERVH subgroups are major contributors to chromatin opening during human embryonic genome activation and act as KLF-stimulated enhancers in naïve embryonic stem cells. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
35 Samples
Download data: BED
Series
Accession:
GSE130417
ID:
200130417

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Hominid-specific transposable elements and KRAB-ZFPs facilitate human embryonic genome activation and transcription in naïve hESCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
79 Samples
Download data: BED, TAB
Series
Accession:
GSE117395
ID:
200117395

PubMed Full text in PMC Similar studies

3.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12236 Series
349795 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

4.

Input_+-KLFs_primed_hESC

Organism:
Homo sapiens
Source name:
Input_+-KLFs_primed_hESC
Platform:
GPL16791
Series:
GSE117395 GSE130417
Download data
Sample
Accession:
GSM3738351
ID:
303738351

SRA Run Selector

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db=gds|term=GSM3738351[Accession]|query=1|qty=2|blobid=MCID_6750db108288966b395a5120|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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