GEO DataSets

(Submitter supplied) Several classes of small RNAs have been described, however to molecularly profile them require large numbers of cells. Here, we developed a method for single-cell small-RNA sequencing that we applied to naïve and primed human embryonic stem cells and to cancer cells. Single-cell profiling of microRNAs and fragments of tRNAs and snoRNAs revealed that, in particular, microRNAs have unrecognized potential to separate cell types and states.

Organism:

Homo sapiens; synthetic construct

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL11154 GPL15228

539 Samples

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