GSM2088209[Accession] - GEO DataSets

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Items: 4

Select item 2000792791.

Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tissue-of-origin mapping from plasma DNA

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platforms:: GPL16791 GPL15520 GPL11154
159 Samples

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Series

Accession:: GSE79279

ID:: 200079279

PubMed Full text in PMC Similar studies

Select item 2000792152.

Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tissue-of-origin mapping from plasma DNA [WGBS]

(Submitter supplied) Adjacent CpG sites in mammalian genomes tend to be co-methylated due to the processivity of enzymes responsible for adding or removing the methyl group. Yet discordant methylation patterns have also be observed, and found to be related to stochastic or uncoordinated molecular processes. Here we focused on a systematic search and investigation of regions in the human genome that exhibit highly coordinated methylation. more...