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Items: 5

1.

Normal Calorie Restricted

(Submitter supplied) Normal female Ames mouse (+/+ or +/df) with ad libitum access to water and fed 30% less of the standard pelleted diet with respect to the amount consumed by normal female ad libitum fed +/+ and +/df mice (LabDiet, PMI Feeds, Inc., St Louis, MO) caged with microisolator filter tops. Mice were killed between 24 to 26 months of age, tissues removed, rapidly frozen on dry ice, and stored in liquid nitrogen. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL81
8 Samples
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Series
Accession:
GSE1089
ID:
200001089
2.

caloric restriction

(Submitter supplied) Mice were killed between 24 to 26 months of age, tissues removed, rapidly frozen on dry ice, and stored in liquid nitrogen. Total liver RNA was isolated from frozen tissue as described (T. Tsuchiya, J.M. Dhahbi, X. Cui, P.L. Mote, A. Bartke, S.R. Spindler, Physiological Genomics, Submitted). mRNA levels were measured using the Affymetrix mouse U74Av2 array according to standard protocols. After hybridization, arrays were scanned using a Hewlett-Packard GeneArray Scanner. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1261
Platform:
GPL81
31 Samples
Download data
Series
Accession:
GSE1093
ID:
200001093
3.
Full record GDS1261

GH/IGF-1 signaling disruption and caloric restriction additive effect

Analysis of livers from growth hormone/insulin-like growth factor-1 signaling defective Ames dwarfs (DF) subjected to caloric restriction (CR). DF and CR in combination additively extend life span. Results provide insight into the mechanisms underlying this additive effect.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 protocol sets
Platform:
GPL81
Series:
GSE1093
31 Samples
Download data
DataSet
Accession:
GDS1261
ID:
1261
4.

[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. more...
Organism:
Mus musculus
264 DataSets
537 Series
1 Related Platform
6909 Samples
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Platform
Accession:
GPL81
ID:
100000081
5.

NCR7

Organism:
Mus musculus
Source name:
Phenotypically normal mouse (+/+ or +/df) fed 30% less of standard pelleted diet with respect to the amount consumed by normal female ad libitum fed +/+ and +/df mice
Platform:
GPL81
Series:
GSE1089 GSE1093
Dataset:
GDS1261
Download data
Sample
Accession:
GSM17391
ID:
300017391
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