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Items: 20

1.

Next-generation sequencing facilitates metal homeostasis and intoxication studies

(Submitter supplied) Purpose: Analyze transcriptome changes in response to metal treatment in wildtype and sensitized genetic backgrounds. Methods: Zinc or manganese chloride supplementation of wildtype or mutant Drosophila S2R+ cultured cells, followed by RNA extraction. Results: Zinc chloride supplementation induces transcriptional responses in wildtype, ia-2 mutant, and ZnT63C mutant cells. Conclusions: Wildtype S2R+ cells have a transcriptional response to mild zinc chloride supplementation and the zinc response is greater (in degree and in number of genes) in genetically sensitized cell backgrounds that perturb zinc mobilization.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13304
18 Samples
Download data: CSV
Series
Accession:
GSE99332
ID:
200099332

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
910 Series
18316 Samples
Download data
Platform
Accession:
GPL13304
ID:
100013304

3.

IA2-KO, Mn treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642172
ID:
302642172

SRA Run Selector

4.

IA2-KO, Mn treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642171
ID:
302642171

SRA Run Selector

5.

IA2-KO, Zn treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642170
ID:
302642170

SRA Run Selector

6.

IA2-KO, Zn treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642169
ID:
302642169

SRA Run Selector

7.

IA2-KO, no treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642168
ID:
302642168

SRA Run Selector

8.

IA2-KO, no treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (IA-2 KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642167
ID:
302642167

SRA Run Selector

9.

ZnT63-KO, Mn treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642166
ID:
302642166

SRA Run Selector

10.

ZnT63-KO, Mn treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642165
ID:
302642165

SRA Run Selector

11.

ZnT63-KO, Zn treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642164
ID:
302642164

SRA Run Selector

12.

ZnT63-KO, Zn treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642163
ID:
302642163

SRA Run Selector

13.

ZnT63-KO, no treatment rep2

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642162
ID:
302642162

SRA Run Selector

14.

ZnT63-KO, no treatment rep1

Organism:
Drosophila melanogaster
Source name:
genetically sensitized S2R+ cells (ZnT63C KO)
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642161
ID:
302642161

SRA Run Selector

15.

WT, Mn treatment rep2

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642160
ID:
302642160

SRA Run Selector

16.

WT, Mn treatment rep1

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642159
ID:
302642159

SRA Run Selector

17.

WT, Zn treatment rep2

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642158
ID:
302642158

SRA Run Selector

18.

WT, Zn treatment rep1

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642157
ID:
302642157

SRA Run Selector

19.

WT, no treatment rep2

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642156
ID:
302642156

SRA Run Selector

20.

WT, no treatment rep1

Organism:
Drosophila melanogaster
Source name:
S2R+ cells
Platform:
GPL13304
Series:
GSE99332
Download data: CSV
Sample
Accession:
GSM2642155
ID:
302642155

SRA Run Selector

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