GEO DataSets

(Submitter supplied) Overexpression of glomerular JAK2 mRNA specifically in glomerular podocytes of 129S6 mice led to significant increases in albuminuria, mesangial expansion, glomerulosclerosis, glomerular fibronectin accumulation, and glomerular basement membrane thickening as well as a significant reduction in podocyte density in diabetic mice. Treatment with a specific JAK1/2 inhibitor partly reversed the major phenotypic changes of DKD

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL17400

10 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-2_1-st-v1.na33.2.mm10.transcript.csv #%create_date=Thu Mar 28 17:33:46 2013 PDT #%chip_type=MoGene-2_1-st-v1 #%lib_set_name=MoGene-2_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2012-09-30 #%netaffx-annotation-netaffx-build=33 Protocol: see manufacturer's web site

Organism:

Mus musculus

214 Series

6 Related Platforms

3551 Samples

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