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Items: 1 to 20 of 26

1.

Synthetic lethal screening with small molecule inhibitors provides a pathway to rational combination therapies for melanoma

(Submitter supplied) Recent data demonstrate that extracellular signals are transmitted through a network of proteins rather than hierarchical signaling pathways. This network model suggests why inhibition of a single component of a canonical pathway, even when targeting a mutationally activated driver of cancer, has insufficiently dramatic effects on the treatment of cancer. The biological outcome of signals propagated through a network is inherently more robust and resistant to inhibition of a single network component due to compensatory and redundant signaling events. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
24 Samples
Download data
Series
Accession:
GSE39192
ID:
200039192

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina HumanHT-12 V3.0 expression beadchip

(Submitter supplied) The HumanHT-12 V3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...
Organism:
Homo sapiens
13 DataSets
542 Series
1 Related Platform
26115 Samples
Download data: BGX
Platform
Accession:
GPL6947
ID:
100006947

3.

Cell line SLM2, mutant status WT, condition Treated with Sorafenib+Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Sorafenib+Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957766
ID:
300957766

4.

Cell line SLM2, mutant status WT, condition Treated with Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957765
ID:
300957765

5.

Cell line SLM2, mutant status WT, condition Treated with Sorafenib 2

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Sorafenib
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957764
ID:
300957764

6.

Cell line SLM2, mutant status WT, condition Control 2

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Control
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957763
ID:
300957763

7.

Cell line SLM2, mutant status WT, condition Treated with Sorafenib+Diclofenac 1

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Sorafenib+Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957762
ID:
300957762

8.

Cell line SLM2, mutant status WT, condition Treated with Diclofenac 1

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957761
ID:
300957761

9.

Cell line SLM2, mutant status WT, condition Treated with Sorafenib 1

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Treated with Sorafenib
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957760
ID:
300957760

10.

Cell line SLM2, mutant status WT, condition Control 1

Organism:
Homo sapiens
Source name:
RNA from Cell line SLM2, mutant status WT, condition Control
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957759
ID:
300957759

11.

Cell line DM331, mutant status Braf, condition Treated with Sorafenib+Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Sorafenib+Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957758
ID:
300957758

12.

Cell line DM331, mutant status Braf, condition Treated with Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957757
ID:
300957757

13.

Cell line DM331, mutant status Braf, condition Treated with Sorafenib 2

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Sorafenib
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957756
ID:
300957756

14.

Cell line DM331, mutant status Braf, condition Control 2

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Control
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957755
ID:
300957755

15.

Cell line DM331, mutant status Braf, condition Treated with Sorafenib+Diclofenac 1

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Sorafenib+Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957754
ID:
300957754

16.

Cell line DM331, mutant status Braf, condition Treated with Diclofenac 1

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957753
ID:
300957753

17.

Cell line DM331, mutant status Braf, condition Treated with Sorafenib 1

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Treated with Sorafenib
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957752
ID:
300957752

18.

Cell line DM331, mutant status Braf, condition Control 1

Organism:
Homo sapiens
Source name:
RNA from Cell line DM331, mutant status Braf, condition Control
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957751
ID:
300957751

19.

Cell line VMM39, mutant status Ras, condition Treated with Sorafenib+Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line VMM39, mutant status Ras, condition Treated with Sorafenib+Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957750
ID:
300957750

20.

Cell line VMM39, mutant status Ras, condition Treated with Diclofenac 2

Organism:
Homo sapiens
Source name:
RNA from Cell line VMM39, mutant status Ras, condition Treated with Diclofenac
Platform:
GPL6947
Series:
GSE39192
Download data
Sample
Accession:
GSM957749
ID:
300957749

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