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Items: 1 to 20 of 28

1.

Direct Signaling Between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(Submitter supplied) Interactions of cancer cells with the primary tumor microenvironment are important determinants of cancer progression towards metastasis but it is unknown whether additional prometastatic signals are provided during the intravascular transit to the site of metastasis. Here, we show that transient platelet-tumor cell interactions are sufficient to prime tumor cells for subsequent metastasis. Platelet-derived TGF-beta and direct platelet-tumor cell contacts synergistically activate the TGF-beta/Smad and NF-kappaB pathways in cancer cells, resulting in their transition to an invasive mesenchymal-like phenotype and enhanced metastasis in vivo. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL6096 GPL6246
25 Samples
Download data: CEL
Series
Accession:
GSE27456
ID:
200027456

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Mus musculus
143 DataSets
2504 Series
28 Related Platforms
30419 Samples
Download data
Platform
Accession:
GPL6246
ID:
100006246

3.

[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Wed Mar 11 17:52:08 2009 PDT #%chip_type=MoEx-1_0-st-v1 #%lib_set_name=MoEx-1_0-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07 #%netaffx-annotation-date=2009-03-16 #%netaffx-annotation-netaffx-build=28 Protocol: See manufacturer's web site
Organism:
Mus musculus
237 Series
20 Related Platforms
2981 Samples
Download data
Platform
Accession:
GPL6096
ID:
100006096

4.

R11_790_Sup9

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet releasate co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749325
ID:
300749325

5.

R11_789_PLT9

Organism:
Mus musculus
Source name:
Tumor cells and platelet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749324
ID:
300749324

6.

R11_788_Pellet9

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet pellet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749323
ID:
300749323

7.

R11_787_Pipes9

Organism:
Mus musculus
Source name:
Tumor cells alone
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749322
ID:
300749322

8.

R11_786_Pipes8

Organism:
Mus musculus
Source name:
Tumor cells alone
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749321
ID:
300749321

9.

R11_785_Sup7

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet releasate co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749320
ID:
300749320

10.

R11_784_Pellet7

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet pellet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749319
ID:
300749319

11.

R11_783_PLT7

Organism:
Mus musculus
Source name:
Tumor cells and platelet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749318
ID:
300749318

12.

R11_782_Pipes7

Organism:
Mus musculus
Source name:
Tumor cells alone
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749317
ID:
300749317

13.

R11_723_Sup8

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet releasate co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749316
ID:
300749316

14.

R11_722_Pellet8

Organism:
Mus musculus
Source name:
Tumor cells and centrifuged platelet pellet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749315
ID:
300749315

15.

R11_721_PLT8

Organism:
Mus musculus
Source name:
Tumor cells and platelet co-culture
Platform:
GPL6246
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM749314
ID:
300749314

16.

PHBuf6

Organism:
Mus musculus
Source name:
Tumor cells and platelets combined just prior to RNA isolation
Platform:
GPL6096
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM678469
ID:
300678469

17.

PHBuf5

Organism:
Mus musculus
Source name:
Tumor cells and platelets combined just prior to RNA isolation
Platform:
GPL6096
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM678468
ID:
300678468

18.

PHBuf4

Organism:
Mus musculus
Source name:
Tumor cells and platelets combined just prior to RNA isolation
Platform:
GPL6096
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM678467
ID:
300678467

19.

PLT5

Organism:
Mus musculus
Source name:
Tumor cells and platelet co-culture
Platform:
GPL6096
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM678466
ID:
300678466

20.

PLT4

Organism:
Mus musculus
Source name:
Tumor cells and platelet co-culture
Platform:
GPL6096
Series:
GSE27456
Download data: CEL
Sample
Accession:
GSM678465
ID:
300678465

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