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A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes.
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NextSeq 550 (Homo sapiens)
Illumina NextSeq 500 (Homo sapiens)
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sgRNA counts (day 18, venetoclax selection) rep2
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sgRNA counts (day 18, venetoclax selection) rep1
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RS411 nascent RNA-seq MLL-AF4 siRNA rep3
RS411 nascent RNA-seq MLL-AF4 siRNA rep2
RS411 nascent RNA-seq MLL-AF4 siRNA rep1
RS411 nascent RNA-seq control rep3
RS411 nascent RNA-seq control rep2
RS411 nascent RNA-seq control rep1
SEM nascent RNA-seq RUNX1 siRNA rep3
SEM nascent RNA-seq RUNX1 siRNA rep2
SEM nascent RNA-seq RUNX1 siRNA rep1
SEM nascent RNA-seq control rep3
SEM nascent RNA-seq control rep2
SEM nascent RNA-seq control rep1
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