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Literature

PubMed

PubMed® comprises more than 38 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Featured Bookshelf titles

Drug Therapy for Early Rheumatoid Arthritis

A Systematic Review Update

Donahue KE, Gartlehner G, Schulman ER, et al.

LiverTox

Clinical and Research Information on Drug-Induced Liver Injury

Browse the Bookshelf

Literature databases

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Data

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein sequence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information

News

Research news

The Scientist AUG. 13, 2024

Study Reveals a Cell-Eat-Cell World

From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life

The Scientist AUG. 8, 2024

Researchers Bioengin-Ear Tissue Scaffolds to Human Scale

A new approach to sculpting human-like ears merges 3D printing, xenografts, and tissue engineering.

NPR News AUG. 8, 2024

Do cats experience grief? New research suggests they might

Joe Hernandez

Researchers from Oakland University surveyed hundreds of cat caregivers and found that cats exhibited behaviors associated with grief after a fellow cat or dog in the household died.

More news

Recent blog posts

NIH Director's Blog YESTERDAY

Study Suggests New Experiences Can Refresh Memories of Past Events, with Implications for Understanding PTSD

Your memories of life experiences are encoded in collections of neurons in the brain that were active at the time the event took place. Later, those same patterns of neural activity are replayed in your mind to help stabilize your memories of past events. But new research suggests those memories aren’t fixed. An NIH-supported study in male mice reveals how an older memory can be “refreshed” and altered by association with newer events. The findings, reported in Nature, show that a memory of a recent negative event can become linked to the memory of a neutral event that took place days earlier, changing the way it’s remembered. This provides important insight into what we know about how the brain updates and reorganizes memories based on new information. These findings could also have implications for our understanding of neurobiological processes that might occur in the brain in memory-related mental health conditions like post-traumatic stress disorder (PTSD), when people feel stress or fear even in situations that present no danger.

NCBI Insights DEC. 4, 2024

AGP Files Will No Longer be Accepted for Genome Submissions

Effective March 2025  Do you submit genomes to NCBI’s GenBank? Beginning March 2025, GenBank will no longer accept AGP files for genome submissions. Historically, AGP files were submitted along with contigs as necessary information for constructing assemblies. However, thanks to technology improvements, more and more whole genome shotgun (WGS) sequences submitted to NCBI are gapped … Continue reading AGP Files Will No Longer be Accepted for Genome Submissions

NLM Musings DEC. 4, 2024

Evolving with Science: Introducing NLM’s New Division of Intramural Research

NLM is proud to introduce the new Division of Intramural Research (previously the Intramural Research Program)! This reorganization marks a significant milestone in advancing our research efforts in computational health and biology, with a particular focus on AI and machine learning.