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Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their pro-drugs as anti...
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
THE CRYSTAL STRUCTURE OF HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE WITH BOUND GMP[TRANSFERASE (GLYCOSYLTRANSFERASE)]
HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR[PHOSPHORIBOSYLTRANSFERASE]
TERNARY COMPLEX STRUCTURE OF HUMAN HGPRTASE, PRPP, MG2+, AND THE INHIBITOR HPP REVEALS THE INVOLVEMENT OF THE FLEXIBLE LOOP IN SUBSTRATE BINDING[TRANSFERASE]
Free human HGPRT[TRANSFERASE]
View in iCn3D Similar StructuresPubMedProteinsConserved Domains
Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases[TRANSFERASE]
Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine[TRANSFERASE]
Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)hypoxanthine[TRANSFERASE]
Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)guanine[TRANSFERASE]
Human hypoxanthine-guanine phosphoribosyltransferase in complex with [(2-((Guanine-9H-yl)methyl)propane-1,3-diyl)bis(oxy)]bis(methylene))diphosphonic acid[TRANSFERASE]
Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with 6-fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) ribose-5'-monophosphate[TRANSFERASE]
Human hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((R)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine[TRANSFERASE/INHIBITOR]
Human HGPRT in complex with (S)-HPEPG, an acyclic nucleoside phosphonate[TRANSFERASE/TRANSFERASE Inhibitor]
Human HGPRT in complex with (S)-HPEPHx, an acyclic nucleoside phosphonate[TRANSFERASE/TRANSFERASE Inhibitor]
Human hypoxanthine-guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine[TRANSFERASE]
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