1D6N: TERNARY COMPLEX STRUCTURE OF HUMAN HGPRTASE, PRPP, MG2+, AND THE INHIBITOR HPP REVEALS THE INVOLVEMENT OF THE FLEXIBLE LOOP IN SUBSTRATE BINDING

PDB ID: 1D6NDownload
MMDB ID: 11693
PDB Deposition Date: 1999/10/14
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 1D6N: dimeric; determined by author and by software (PISA)
Molecular Components in 1D6N
Label Count Molecule
Proteins (2 molecules)
2
Protein (Hypoxanthine-guanine Phosphoribosyltransferase)
(Gene symbol: HPRT1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
3H-PYRAZOLO[4,3-D]PYRIMIDIN-7-OL3H-PYRAZOLO[4,3-D]PYRIMIDIN-7-OL
3
2
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303