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Items: 1 to 20 of 1000

1.

rs1491558991 [Homo sapiens]
    Variant type:
    DEL
    Alleles:
    CC>- [Show Flanks]
    Chromosome:
    6:2961762 (GRCh38)
    6:2961996 (GRCh37)
    Canonical SPDI:
    NC_000006.12:2961761:CC:
    Gene:
    SERPINB6 (Varview)
    Functional Consequence:
    intron_variant,5_prime_UTR_variant
    Validated:
    by frequency,by alfa
    MAF:
    -=0.0005/2 (ALFA)
    -=0.0005/2 (Estonian)
    HGVS:
    2.

    rs1491492952 has merged into rs74478488 [Homo sapiens]
      Variant type:
      DELINS
      Alleles:
      TTTTTTT>-,TTTT,TTTTT,TTTTTT,TTTTTTTT,TTTTTTTTT [Show Flanks]
      Chromosome:
      6:2974166 (GRCh38)
      6:2974400 (GRCh37)
      Canonical SPDI:
      NC_000006.12:2974163:TTTTTTTTT:TT,NC_000006.12:2974163:TTTTTTTTT:TTTTTT,NC_000006.12:2974163:TTTTTTTTT:TTTTTTT,NC_000006.12:2974163:TTTTTTTTT:TTTTTTTT,NC_000006.12:2974163:TTTTTTTTT:TTTTTTTTTT,NC_000006.12:2974163:TTTTTTTTT:TTTTTTTTTTT
      Validated:
      by frequency,by alfa,by cluster
      MAF:
      TTTTTTTTTTT=0./0 (ALFA)
      T=0.000495/8 (TOMMO)
      -=0.007025/35 (1000Genomes)
      -=0.008784/2325 (TOPMED)
      T=0.01002/10 (GoNL)
      T=0.011706/7 (NorthernSweden)
      T=0.024363/109 (Estonian)
      T=0.02589/96 (TWINSUK)
      T=0.027763/107 (ALSPAC)
      HGVS:
      3.

      rs1491324947 has merged into rs5873848 [Homo sapiens]
        Variant type:
        DELINS
        Alleles:
        AAAA>-,A,AA,AAA,AAAAA,AAAAAA,AAAAAAAA,AAAAAAAAAAA,AAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAA [Show Flanks]
        Chromosome:
        6:2950546 (GRCh38)
        6:2950780 (GRCh37)
        Canonical SPDI:
        NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2950532:AAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
        Gene:
        SERPINB6 (Varview)
        Functional Consequence:
        intron_variant
        Validated:
        by frequency,by alfa,by cluster
        MAF:
        AAAAAAAAAAAAAAA=0./0 (ALFA)
        A=0.0332/123 (TWINSUK)
        A=0.0361/139 (ALSPAC)
        A=0.3113/1559 (1000Genomes)
        A=0.4/16 (GENOME_DK)
        HGVS:
        NC_000006.12:g.2950546_2950549del, NC_000006.12:g.2950547_2950549del, NC_000006.12:g.2950548_2950549del, NC_000006.12:g.2950549del, NC_000006.12:g.2950549dup, NC_000006.12:g.2950548_2950549dup, NC_000006.12:g.2950546_2950549dup, NC_000006.12:g.2950543_2950549dup, NC_000006.12:g.2950538_2950549dup, NC_000006.12:g.2950537_2950549dup, NC_000006.12:g.2950533_2950549dup, NC_000006.11:g.2950780_2950783del, NC_000006.11:g.2950781_2950783del, NC_000006.11:g.2950782_2950783del, NC_000006.11:g.2950783del, NC_000006.11:g.2950783dup, NC_000006.11:g.2950782_2950783dup, NC_000006.11:g.2950780_2950783dup, NC_000006.11:g.2950777_2950783dup, NC_000006.11:g.2950772_2950783dup, NC_000006.11:g.2950771_2950783dup, NC_000006.11:g.2950767_2950783dup, NG_027692.1:g.26630_26633del, NG_027692.1:g.26631_26633del, NG_027692.1:g.26632_26633del, NG_027692.1:g.26633del, NG_027692.1:g.26633dup, NG_027692.1:g.26632_26633dup, NG_027692.1:g.26630_26633dup, NG_027692.1:g.26627_26633dup, NG_027692.1:g.26622_26633dup, NG_027692.1:g.26621_26633dup, NG_027692.1:g.26617_26633dup
        4.

        rs1491137271 [Homo sapiens]
          Variant type:
          INS
          Alleles:
          ->A [Show Flanks]
          Chromosome:
          6:2961762 (GRCh38)
          6:2961997 (GRCh37)
          Canonical SPDI:
          NC_000006.12:2961762::A
          Gene:
          SERPINB6 (Varview)
          Functional Consequence:
          5_prime_UTR_variant,intron_variant
          Validated:
          by frequency,by alfa
          MAF:
          A=0./0 (ALFA)
          A=0.00046/2 (Estonian)
          HGVS:
          5.

          rs1491075698 has merged into rs70995402 [Homo sapiens]
            Variant type:
            DELINS
            Alleles:
            AAAAAAAAAAAA>-,A,AA,AAA,AAAA,AAAAA,AAAAAA,AAAAAAA,AAAAAAAA,AAAAAAAAA,AAAAAAAAAA,AAAAAAAAAAA,AAAAAAAAAAAAA,AAAAAAAAAAAAAA,AAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAA,AAAAAAAAAAAAAAAAAAAAAAAA [Show Flanks]
            Chromosome:
            6:2970733 (GRCh38)
            6:2970967 (GRCh37)
            Canonical SPDI:
            NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAA,NC_000006.12:2970724:AAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
            Gene:
            SERPINB6 (Varview)
            Functional Consequence:
            genic_upstream_transcript_variant,upstream_transcript_variant,intron_variant
            Clinical significance:
            benign,likely-benign
            Validated:
            by frequency,by alfa,by cluster
            MAF:
            AAAAAAAA=0./0 (ALFA)
            HGVS:
            NC_000006.12:g.2970733_2970744del, NC_000006.12:g.2970734_2970744del, NC_000006.12:g.2970735_2970744del, NC_000006.12:g.2970736_2970744del, NC_000006.12:g.2970737_2970744del, NC_000006.12:g.2970738_2970744del, NC_000006.12:g.2970739_2970744del, NC_000006.12:g.2970740_2970744del, NC_000006.12:g.2970741_2970744del, NC_000006.12:g.2970742_2970744del, NC_000006.12:g.2970743_2970744del, NC_000006.12:g.2970744del, NC_000006.12:g.2970744dup, NC_000006.12:g.2970743_2970744dup, NC_000006.12:g.2970742_2970744dup, NC_000006.12:g.2970741_2970744dup, NC_000006.12:g.2970740_2970744dup, NC_000006.12:g.2970739_2970744dup, NC_000006.12:g.2970736_2970744dup, NC_000006.12:g.2970733_2970744dup, NC_000006.11:g.2970967_2970978del, NC_000006.11:g.2970968_2970978del, NC_000006.11:g.2970969_2970978del, NC_000006.11:g.2970970_2970978del, NC_000006.11:g.2970971_2970978del, NC_000006.11:g.2970972_2970978del, NC_000006.11:g.2970973_2970978del, NC_000006.11:g.2970974_2970978del, NC_000006.11:g.2970975_2970978del, NC_000006.11:g.2970976_2970978del, NC_000006.11:g.2970977_2970978del, NC_000006.11:g.2970978del, NC_000006.11:g.2970978dup, NC_000006.11:g.2970977_2970978dup, NC_000006.11:g.2970976_2970978dup, NC_000006.11:g.2970975_2970978dup, NC_000006.11:g.2970974_2970978dup, NC_000006.11:g.2970973_2970978dup, NC_000006.11:g.2970970_2970978dup, NC_000006.11:g.2970967_2970978dup, NG_027692.1:g.6430_6441del, NG_027692.1:g.6431_6441del, NG_027692.1:g.6432_6441del, NG_027692.1:g.6433_6441del, NG_027692.1:g.6434_6441del, NG_027692.1:g.6435_6441del, NG_027692.1:g.6436_6441del, NG_027692.1:g.6437_6441del, NG_027692.1:g.6438_6441del, NG_027692.1:g.6439_6441del, NG_027692.1:g.6440_6441del, NG_027692.1:g.6441del, NG_027692.1:g.6441dup, NG_027692.1:g.6440_6441dup, NG_027692.1:g.6439_6441dup, NG_027692.1:g.6438_6441dup, NG_027692.1:g.6437_6441dup, NG_027692.1:g.6436_6441dup, NG_027692.1:g.6433_6441dup, NG_027692.1:g.6430_6441dup
            6.

            rs1491028570 [Homo sapiens]
              Variant type:
              DELINS
              Alleles:
              TA>- [Show Flanks]
              Chromosome:
              6:2951402 (GRCh38)
              6:2951636 (GRCh37)
              Canonical SPDI:
              NC_000006.12:2951400:ATA:A
              Gene:
              SERPINB6 (Varview)
              Functional Consequence:
              intron_variant
              Validated:
              by frequency,by alfa,by cluster
              MAF:
              A=0./0 (ALFA)
              -=0.001183/164 (GnomAD)
              -=0.008197/15 (Korea1K)
              HGVS:
              7.

              rs1491009740 has merged into rs34187484 [Homo sapiens]
                Variant type:
                DELINS
                Alleles:
                AAA>-,A,AA,AAAA,AAAAA,AAAAAA,AAAAAAAAAAAA [Show Flanks]
                Chromosome:
                6:2956834 (GRCh38)
                6:2957068 (GRCh37)
                Canonical SPDI:
                NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA,NC_000006.12:2956821:AAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAA
                Gene:
                SERPINB6 (Varview)
                Functional Consequence:
                intron_variant
                Validated:
                by frequency,by alfa,by cluster
                MAF:
                AAAAAAAAAAAAAAAAA=0.0004/3 (ALFA)
                -=0.3167/1586 (1000Genomes)
                HGVS:
                8.

                rs1490874997 [Homo sapiens]
                  Variant type:
                  SNV:
                  Alleles:
                  A>C
                  Chromosome:
                  no mapping
                  Canonical SPDI:
                  9.

                  rs1490859396 [Homo sapiens]
                    Variant type:
                    SNV
                    Alleles:
                    C>T [Show Flanks]
                    Chromosome:
                    6:2967704 (GRCh38)
                    6:2967938 (GRCh37)
                    Canonical SPDI:
                    NC_000006.12:2967703:C:T
                    Gene:
                    SERPINB6 (Varview)
                    Functional Consequence:
                    genic_upstream_transcript_variant,intron_variant
                    Validated:
                    by frequency,by alfa,by cluster
                    MAF:
                    T=0./0 (ALFA)
                    T=0.000029/4 (GnomAD)
                    T=0.000034/9 (TOPMED)
                    HGVS:
                    10.

                    rs1490670713 [Homo sapiens]
                      Variant type:
                      SNV
                      Alleles:
                      T>G [Show Flanks]
                      Chromosome:
                      6:2967351 (GRCh38)
                      6:2967585 (GRCh37)
                      Canonical SPDI:
                      NC_000006.12:2967350:T:G
                      Gene:
                      SERPINB6 (Varview)
                      Functional Consequence:
                      genic_upstream_transcript_variant,intron_variant
                      Validated:
                      by frequency,by alfa
                      MAF:
                      G=0./0 (ALFA)
                      HGVS:
                      11.

                      rs1490538302 [Homo sapiens]
                        Variant type:
                        SNV
                        Alleles:
                        A>G [Show Flanks]
                        Chromosome:
                        6:2968494 (GRCh38)
                        6:2968728 (GRCh37)
                        Canonical SPDI:
                        NC_000006.12:2968493:A:G
                        Gene:
                        SERPINB6 (Varview)
                        Functional Consequence:
                        genic_upstream_transcript_variant,intron_variant
                        Validated:
                        by frequency,by alfa
                        MAF:
                        G=0./0 (ALFA)
                        G=0.000007/1 (GnomAD)
                        HGVS:
                        12.

                        rs1490493190 [Homo sapiens]
                          Variant type:
                          DELINS
                          Alleles:
                          CT>- [Show Flanks]
                          Chromosome:
                          6:2949151 (GRCh38)
                          6:2949385 (GRCh37)
                          Canonical SPDI:
                          NC_000006.12:2949146:CTCTCT:CTCT
                          Gene:
                          SERPINB6 (Varview)
                          Functional Consequence:
                          intron_variant
                          Validated:
                          by frequency,by alfa,by cluster
                          MAF:
                          CTCT=0.000094/1 (ALFA)
                          -=0.000007/1 (GnomAD)
                          -=0.000015/4 (TOPMED)
                          HGVS:
                          13.

                          rs1490126279 [Homo sapiens]
                            Variant type:
                            SNV
                            Alleles:
                            T>C [Show Flanks]
                            Chromosome:
                            6:2964087 (GRCh38)
                            6:2964321 (GRCh37)
                            Canonical SPDI:
                            NC_000006.12:2964086:T:C
                            Gene:
                            SERPINB6 (Varview)
                            Functional Consequence:
                            genic_upstream_transcript_variant,upstream_transcript_variant,intron_variant
                            Validated:
                            by frequency,by alfa,by cluster
                            MAF:
                            C=0.000071/1 (ALFA)
                            C=0.000021/3 (GnomAD)
                            C=0.000026/7 (TOPMED)
                            HGVS:
                            14.

                            rs1490042925 [Homo sapiens]
                              Variant type:
                              SNV
                              Alleles:
                              G>T [Show Flanks]
                              Chromosome:
                              6:2966340 (GRCh38)
                              6:2966574 (GRCh37)
                              Canonical SPDI:
                              NC_000006.12:2966339:G:T
                              Gene:
                              SERPINB6 (Varview)
                              Functional Consequence:
                              genic_upstream_transcript_variant,intron_variant
                              Validated:
                              by frequency,by alfa
                              MAF:
                              T=0.0031/14 (ALFA)
                              T=0.0031/14 (Estonian)
                              HGVS:
                              15.

                              rs1489905989 [Homo sapiens]
                                Variant type:
                                SNV
                                Alleles:
                                T>C [Show Flanks]
                                Chromosome:
                                6:2965382 (GRCh38)
                                6:2965616 (GRCh37)
                                Canonical SPDI:
                                NC_000006.12:2965381:T:C
                                Gene:
                                SERPINB6 (Varview)
                                Functional Consequence:
                                genic_upstream_transcript_variant,intron_variant
                                Validated:
                                by frequency,by alfa,by cluster
                                MAF:
                                C=0./0 (ALFA)
                                C=0.000014/2 (GnomAD)
                                C=0.00003/8 (TOPMED)
                                HGVS:
                                16.

                                rs1489675577 [Homo sapiens]
                                  Variant type:
                                  SNV
                                  Alleles:
                                  G>C [Show Flanks]
                                  Chromosome:
                                  6:2965185 (GRCh38)
                                  6:2965419 (GRCh37)
                                  Canonical SPDI:
                                  NC_000006.12:2965184:G:C
                                  Gene:
                                  SERPINB6 (Varview)
                                  Functional Consequence:
                                  genic_upstream_transcript_variant,intron_variant
                                  Validated:
                                  by frequency,by alfa,by cluster
                                  MAF:
                                  C=0./0 (ALFA)
                                  C=0.000004/1 (TOPMED)
                                  C=0.000007/1 (GnomAD)
                                  HGVS:
                                  17.

                                  rs1489666264 [Homo sapiens]
                                    Variant type:
                                    SNV
                                    Alleles:
                                    T>C [Show Flanks]
                                    Chromosome:
                                    6:2962479 (GRCh38)
                                    6:2962713 (GRCh37)
                                    Canonical SPDI:
                                    NC_000006.12:2962478:T:C
                                    Gene:
                                    SERPINB6 (Varview)
                                    Functional Consequence:
                                    genic_upstream_transcript_variant,upstream_transcript_variant,intron_variant
                                    Validated:
                                    by frequency,by alfa,by cluster
                                    MAF:
                                    C=0./0 (ALFA)
                                    C=0.000014/2 (GnomAD)
                                    C=0.000026/7 (TOPMED)
                                    HGVS:
                                    18.

                                    rs1489614641 [Homo sapiens]
                                      Variant type:
                                      SNV
                                      Alleles:
                                      C>T [Show Flanks]
                                      Chromosome:
                                      6:2957410 (GRCh38)
                                      6:2957644 (GRCh37)
                                      Canonical SPDI:
                                      NC_000006.12:2957409:C:T
                                      Gene:
                                      SERPINB6 (Varview)
                                      Functional Consequence:
                                      intron_variant
                                      Validated:
                                      by frequency,by alfa,by cluster
                                      MAF:
                                      T=0./0 (ALFA)
                                      T=0.000007/1 (GnomAD)
                                      T=0.000011/3 (TOPMED)
                                      HGVS:
                                      19.

                                      rs1489422160 [Homo sapiens]
                                        Variant type:
                                        SNV
                                        Alleles:
                                        T>C [Show Flanks]
                                        Chromosome:
                                        6:2961726 (GRCh38)
                                        6:2961960 (GRCh37)
                                        Canonical SPDI:
                                        NC_000006.12:2961725:T:C
                                        Gene:
                                        SERPINB6 (Varview)
                                        Functional Consequence:
                                        5_prime_UTR_variant,intron_variant
                                        Validated:
                                        by frequency,by alfa,by cluster
                                        MAF:
                                        C=0./0 (ALFA)
                                        C=0.000029/4 (GnomAD)
                                        C=0.000045/12 (TOPMED)
                                        C=0.000312/2 (1000Genomes)
                                        HGVS:
                                        20.

                                        rs1489403036 [Homo sapiens]
                                          Variant type:
                                          SNV
                                          Alleles:
                                          C>T [Show Flanks]
                                          Chromosome:
                                          6:2957288 (GRCh38)
                                          6:2957522 (GRCh37)
                                          Canonical SPDI:
                                          NC_000006.12:2957287:C:T
                                          Gene:
                                          SERPINB6 (Varview)
                                          Functional Consequence:
                                          intron_variant
                                          Validated:
                                          by frequency,by alfa
                                          MAF:
                                          T=0./0 (ALFA)
                                          T=0.000004/1 (TOPMED)
                                          HGVS:

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