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    arhgap46a Rho GTPase activating protein 46a [ Danio rerio (zebrafish) ]

    Gene ID: 492329, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arhgap46aprovided by ZNC
    Official Full Name
    Rho GTPase activating protein 46aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-4
    See related
    Ensembl:ENSDARG00000044874 AllianceGenome:ZFIN:ZDB-GENE-041114-4
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92107; wu:fa99h06; wu:fj78h03
    Summary
    Predicted to enable GTPase activator activity. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See arhgap46a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24994770..25041804)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24756903..24804188)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 17 homolog A (yeast) Neighboring gene sulfatase 2a Neighboring gene PHD finger protein 20, a Neighboring gene ndrg family member 3a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC492329

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007295.1 → NP_001007296.1  uncharacterized protein LOC492329

      See identical proteins and their annotated locations for NP_001007296.1

      Status: PREDICTED

      Source sequence(s)
      BC085634
      UniProtKB/TrEMBL
      Q5U3A6
      Related
      ENSDARP00000111144.2, ENSDART00000129211.4
      Conserved Domains (2) summary
      cd04389
      Location:872 → 1057
      RhoGAP_KIAA1688; RhoGAP_KIAA1688: GTPase-activator protein (GAP) domain for Rho-like GTPases found in KIAA1688-like proteins; KIAA1688 is a protein of unknown function that contains a RhoGAP domain and a myosin tail homology 4 (MyTH4) domain. Small GTPases cluster into ...
      cl02480
      Location:675 → 859
      MyTH4; MyTH4 domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      24994770..25041804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169287.5 → XP_005169344.1  uncharacterized protein LOC492329 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BGP1
      Related
      ENSDARP00000134248.2, ENSDART00000167285.2
      Conserved Domains (2) summary
      cd04389
      Location:786 → 971
      RhoGAP_KIAA1688; RhoGAP_KIAA1688: GTPase-activator protein (GAP) domain for Rho-like GTPases found in KIAA1688-like proteins; KIAA1688 is a protein of unknown function that contains a RhoGAP domain and a myosin tail homology 4 (MyTH4) domain. Small GTPases cluster into ...
      cl02480
      Location:589 → 773
      MyTH4; MyTH4 domain

    2. XM_068224156.1 → XP_068080257.1  uncharacterized protein LOC492329 isoform X2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394821.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      180519..231063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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