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ric-3 Resistance to inhibitors of cholinesterase protein 3 [ Caenorhabditis elegans ]

Gene ID: 177570, updated on 4-Jan-2025

Summary

Official Symbol
ric-3
Official Full Name
Resistance to inhibitors of cholinesterase protein 3
Primary source
WormBase:WBGene00004363
Locus tag
CELE_T14A8.1
See related
AllianceGenome:WB:WBGene00004363
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables protein folding chaperone. Involved in several processes, including cholinergic synaptic transmission; positive regulation of cholinergic synaptic transmission; and protein localization to cell surface. Located in intracellular membrane-bounded organelle; neuron projection; and neuronal cell body. Is expressed in body wall musculature; neurons; and pharyngeal muscle cell. Orthologous to human RIC3 (RIC3 acetylcholine receptor chaperone). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See ric-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (7818251..7821195)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Zinc finger CCCH-type with G patch domain-containing protein Neighboring gene Phosphatidate cytidylyltransferase Neighboring gene ncRNA Neighboring gene MS Related Protein Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in endoplasmic reticulum  
located_in endoplasmic reticulum  
located_in endoplasmic reticulum membrane  
is_active_in intracellular membrane-bounded organelle  
located_in intracellular membrane-bounded organelle PubMed 
located_in membrane  
is_active_in neuron projection  
located_in neuron projection PubMed 
is_active_in neuronal cell body  
located_in neuronal cell body PubMed 
located_in synapse  

General protein information

Preferred Names
Resistance to inhibitors of cholinesterase protein 3
NP_501299.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7818251..7821195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068898.7NP_501299.1  Resistance to inhibitors of cholinesterase protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501299.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22472
    Conserved Domains (1) summary
    pfam15361
    Location:52204
    RIC3; Resistance to inhibitors of cholinesterase homologue 3
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