U.S. flag

An official website of the United States government

Abca13 ATP-binding cassette, sub-family A member 13 [ Mus musculus (house mouse) ]

Gene ID: 268379, updated on 4-Jan-2025

Summary

Official Symbol
Abca13provided by MGI
Official Full Name
ATP-binding cassette, sub-family A member 13provided by MGI
Primary source
MGI:MGI:2388707
See related
Ensembl:ENSMUSG00000004668 AllianceGenome:MGI:2388707
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9830132L24; A930002G16Rik
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Involved in ceramide transport; positive regulation of cholesterol transport; and positive regulation of synaptic vesicle endocytosis. Located in intracellular vesicle. Is expressed in bone marrow; genitourinary system; and retina. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Orthologous to human ABCA13 (ATP binding cassette subfamily A member 13). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in kidney adult (RPKM 3.8) and liver E18 (RPKM 0.4) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Abca13 in Genome Data Viewer
Location:
11 A1; 11 6.13 cM
Exon count:
62
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (9141942..9634871)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (9191942..9684871)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_28553 Neighboring gene STARR-seq mESC enhancer starr_28555 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide C pseudogene Neighboring gene uridine phosphorylase 1 Neighboring gene STARR-seq mESC enhancer starr_28556 Neighboring gene STARR-seq mESC enhancer starr_28557 Neighboring gene STARR-seq mESC enhancer starr_28558 Neighboring gene STARR-seq mESC enhancer starr_28559 Neighboring gene STARR-seq mESC enhancer starr_28560 Neighboring gene STARR-seq mESC enhancer starr_28561 Neighboring gene STARR-seq mESC enhancer starr_28562 Neighboring gene STARR-seq mESC enhancer starr_28564 Neighboring gene eukaryotic translation initiation factor 3, subunit 6, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_28567 Neighboring gene STARR-seq mESC enhancer starr_28570 Neighboring gene STARR-seq mESC enhancer starr_28571 Neighboring gene STARR-seq mESC enhancer starr_28573 Neighboring gene STARR-seq mESC enhancer starr_28574 Neighboring gene STARR-seq mESC enhancer starr_28576 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3)  1 citation
  • Targeted (3) 

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ABC-type transporter activity  
enables ATP binding  
enables ATP hydrolysis activity  
enables ATPase-coupled transmembrane transporter activity  
enables lipid transporter activity  
Component Evidence Code Pubs
located_in cytoplasmic vesicle membrane  
is_active_in intracellular membrane-bounded organelle  
located_in intracellular vesicle PubMed 
located_in intracellular vesicle  

General protein information

Preferred Names
ATP-binding cassette sub-family A member 13
Names
ATP-binding cassette transporter
ATP-binding cassette, sub-family A (ABC1), member 13

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178259.3NP_839990.2  ATP-binding cassette sub-family A member 13

    See identical proteins and their annotated locations for NP_839990.2

    Status: VALIDATED

    Source sequence(s)
    AL645994, AL663110, AL663114, AL669853
    Consensus CDS
    CCDS36110.1
    UniProtKB/Swiss-Prot
    Q5SSE9, Q80T20, Q8BHZ2, Q8CB91
    Related
    ENSMUSP00000040465.7, ENSMUST00000042740.13
    Conserved Domains (2) summary
    TIGR01257
    Location:30365019
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:46924919
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    9141942..9634871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514706.5XP_006514769.2  ATP-binding cassette sub-family A member 13 isoform X1

    Conserved Domains (1) summary
    TIGR01257
    Location:22054150
    rim_protein; retinal-specific rim ABC transporter
External link. Please review our privacy policy.