U.S. flag

An official website of the United States government

nudC nudC [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39879, updated on 4-Jan-2025

Summary

Official Symbol
nudCprovided by FlyBase
Official Full Name
nudCprovided by FlyBase
Primary source
FLYBASE:FBgn0021768
Locus tag
Dmel_CG9710
See related
AllianceGenome:FB:FBgn0021768
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9710; Dmel\CG9710; DnudC; NudC; NUDC; Q9VVA6
Summary
Predicted to enable unfolded protein binding activity. Involved in nucleus localization and positive regulation of dendrite morphogenesis. Located in cytoplasm. Is expressed in several structures, including adult brain cell body rind; embryonic/larval midgut primordium; sense organ; sensory nervous system primordium; and somatic trunk mesoderm derivative. Orthologous to human NUDC (nuclear distribution C, dynein complex regulator). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See nudC in Genome Data Viewer
Location:
73C5-73D1; 3-45 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16804994..16819532)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16798094..16812632)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit e Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Tumor susceptibility gene 101 Neighboring gene Zinc finger CCHC-type containing 7 Neighboring gene uncharacterized protein Neighboring gene kuduk

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables unfolded protein binding  
Process Evidence Code Pubs
involved_in nuclear migration PubMed 
involved_in nucleus localization PubMed 
involved_in positive regulation of dendrite morphogenesis PubMed 
involved_in protein folding  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm PubMed 
located_in cytosol PubMed 

General protein information

Preferred Names
nudC
Names
CG9710-PA
CG9710-PB
nudC-PA
nudC-PB

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16804994..16819532
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259876.1 → NP_001246805.1  nudC, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246805.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SYK7, Q9VVA6
    Conserved Domains (2) summary
    cd06492
    Location:173 → 259
    p23_mNUDC_like; p23-like NUD (nuclear distribution) C-like domain of mammalian(m) NUDC and similar proteins. Mammalian(m) NUDC associates both with the dynein complex and also with an anti-inflammatory enzyme, platelet activating factor acetylhydrolase I, PAF-AH(I) ...
    pfam14050
    Location:7 → 58
    Nudc_N; N-terminal conserved domain of Nudc
  2. NM_140666.4 → NP_648923.1  nudC, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648923.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SYK7, Q9VVA6
    Related
    FBpp0075087
    Conserved Domains (2) summary
    cd06492
    Location:173 → 259
    p23_mNUDC_like; p23-like NUD (nuclear distribution) C-like domain of mammalian(m) NUDC and similar proteins. Mammalian(m) NUDC associates both with the dynein complex and also with an anti-inflammatory enzyme, platelet activating factor acetylhydrolase I, PAF-AH(I) ...
    pfam14050
    Location:7 → 58
    Nudc_N; N-terminal conserved domain of Nudc
External link. Please review our privacy policy.