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    MagR Magnetic receptor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32513, updated on 9-Dec-2024

    Summary

    Official Symbol
    MagRprovided by FlyBase
    Official Full Name
    Magnetic receptorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026666
    Locus tag
    Dmel_CG8198
    See related
    AllianceGenome:FB:FBgn0026666
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT26381; CG8198; dMagR; Dmel\CG8198; IscA1; l(1)G0136
    Summary
    Predicted to enable 2 iron, 2 sulfur cluster binding activity. Involved in response to magnetism. Predicted to be part of mitochondrial [4Fe-4S] assembly complex. Predicted to be active in mitochondrion. Is expressed in adult head. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 5. Orthologous to human ISCA1 (iron-sulfur cluster assembly 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See MagR in Genome Data Viewer
    Location:
    13E12-13E12; 1-51 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15734270..15735780)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15628303..15629813)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding  
    enables iron-sulfur cluster binding  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    part_of mitochondrial [4Fe-4S] assembly complex  
    is_active_in mitochondrial matrix PubMed 
    is_active_in mitochondrion  

    General protein information

    Preferred Names
    magnetic receptor
    Names
    CG8198-PA
    CG8198-PB
    IscA1 homologue
    MagR-PA
    MagR-PB
    lethal (1) G0136
    magnetoreceptor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15734270..15735780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272650.1NP_001259579.1  magnetic receptor, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259579.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T3X9
      Conserved Domains (1) summary
      TIGR00049
      Location:27130
      TIGR00049; Iron-sulfur cluster assembly accessory protein
    2. NM_132834.2NP_573062.1  magnetic receptor, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573062.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PJN7, Q8T3X9, Q9VXR0
      Related
      FBpp0073900
      Conserved Domains (1) summary
      TIGR00049
      Location:27129
      TIGR00049; Iron-sulfur cluster assembly accessory protein
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