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Arr1 Arrestin 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35078, updated on 9-Dec-2024

Summary

Official Symbol
Arr1provided by FlyBase
Official Full Name
Arrestin 1provided by FlyBase
Primary source
FLYBASE:FBgn0000120
Locus tag
Dmel_CG5711
See related
AllianceGenome:FB:FBgn0000120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
3H10; Arr; arr1; ARR1; ArrA; CG5711; DA; DAI; DmArr1; Dmarrestin; DmArrestin-1; Dmel\CG5711; Dro.-Arr.I; DS-Ag; PRII
Summary
Predicted to enable G protein-coupled receptor binding activity and opsin binding activity. Involved in several processes, including negative regulation of G protein-coupled receptor signaling pathway; photoreceptor cell maintenance; and sensory perception of smell. Located in cytoplasm and rhabdomere. Is expressed in several structures, including adult head; photoreceptor; retina; rhabdomere; and testis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Arr1 in Genome Data Viewer
Location:
36E3-36E3; 2-53 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18078269..18081307)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18078269..18081307)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene elfless Neighboring gene reduced ocelli Neighboring gene neither inactivation nor afterpotential D Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor binding  
enables opsin binding PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm PubMed 
located_in rhabdomere PubMed 

General protein information

Preferred Names
arrestin 1
Names
Arr1-PA
Arr1-PB
Arr1-PC
Arrestin1
CG5711-PA
CG5711-PB
CG5711-PC
Phosrestin-II
arrestin
arrestin A
drosophila arrestin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18078269..18081307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259144.2 → NP_001246073.1  arrestin 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246073.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15372, Q9VJA8
    UniProtKB/TrEMBL
    M9NES0
    Conserved Domains (2) summary
    smart01017
    Location:192 → 350
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    cl22903
    Location:17 → 173
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain
  2. NM_057333.4 → NP_476681.1  arrestin 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476681.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15372, Q9VJA8
    UniProtKB/TrEMBL
    M9NES0
    Related
    FBpp0080583
    Conserved Domains (2) summary
    smart01017
    Location:192 → 350
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    cl22903
    Location:17 → 173
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain
  3. NM_001299096.1 → NP_001286025.1  arrestin 1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286025.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J8V5
    Conserved Domains (2) summary
    smart01017
    Location:178 → 336
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    cl22903
    Location:23 → 159
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain
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