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CG7049 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38022, updated on 9-Dec-2024

Summary

Official Symbol
CG7049provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035102
Locus tag
Dmel_CG7049
See related
AllianceGenome:FB:FBgn0035102
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7049
Summary
Predicted to enable formylglycine-generating oxidase activity. Predicted to be involved in protein modification process. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in mucosulfatidosis. Orthologous to human SUMF1 (sulfatase modifying factor 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CG7049 in Genome Data Viewer
Location:
61B2-61B2; 3-1 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (175112..176228, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (175112..176228, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Dynein intermediate chain at 61B Neighboring gene p130CAS Neighboring gene long non-coding RNA:CR43151 Neighboring gene antisense RNA:CR45806 Neighboring gene Vitamin D[[3]] up-regulated protein 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene MAP kinase-specific phosphatase

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables formylglycine-generating oxidase activity  
enables formylglycine-generating oxidase activity  
Process Evidence Code Pubs
involved_in protein modification process  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum  
located_in endoplasmic reticulum  

General protein information

Preferred Names
uncharacterized protein
Names
CG7049-PA
NP_612003.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    175112..176228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138159.4NP_612003.1  uncharacterized protein Dmel_CG7049 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612003.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPQ4, Q9W0U6
    Related
    FBpp0072436
    Conserved Domains (2) summary
    COG1262
    Location:65336
    YfmG; Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones]
    pfam03781
    Location:65334
    FGE-sulfatase; Sulfatase-modifying factor enzyme 1
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