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Sytbeta Synaptotagmin beta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39630, updated on 9-Dec-2024

Summary

Official Symbol
Sytbetaprovided by FlyBase
Official Full Name
Synaptotagmin betaprovided by FlyBase
Primary source
FLYBASE:FBgn0261090
Locus tag
Dmel_CG42333
See related
AllianceGenome:FB:FBgn0261090
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13462; CG3020; CG42333; Dmel\CG42333; dsytbeta; Syt beta; Syt V; SYT-beta; syt13; Syt13; sytbeta; SytV
Old locus tag
Dmel_CG13462; Dmel_CG3020
Summary
Predicted to enable SNARE binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in regulation of calcium ion-dependent exocytosis and synaptic vesicle exocytosis. Predicted to be located in membrane and synaptic vesicle. Predicted to be active in exocytic vesicle and plasma membrane. Is expressed in several structures, including adult brain cell body rind; adult gnathal ganglion; adult neuromere; synaptic neuropil domain; and synaptic neuropil layer. Orthologous to human SYT13 (synaptotagmin 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Sytbeta in Genome Data Viewer
Location:
71B1-71B2; 3-42 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15014695..15064977, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15007795..15058077, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Zinc/iron regulated transporter-related protein 71B Neighboring gene Proteasome beta2 subunit Neighboring gene mitochondrial ribosomal protein L39 Neighboring gene Reversion-inducing-cysteine-rich protein with kazal motifs Neighboring gene uncharacterized protein Neighboring gene Regulatory particle non-ATPase 12-related Neighboring gene intermediate neuroblasts defective Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43684 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Enhancer of Acetyltransferase Chameau Neighboring gene uncharacterized protein Neighboring gene Pericentrin-like protein Neighboring gene Odorant receptor 71a Neighboring gene stepping stone

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SNARE binding  
enables calcium ion sensor activity  
enables calcium-dependent phospholipid binding  
Process Evidence Code Pubs
involved_in chemical synaptic transmission  
involved_in regulation of calcium ion-dependent exocytosis  
involved_in synaptic vesicle exocytosis PubMed 
involved_in vesicle-mediated transport  
Component Evidence Code Pubs
is_active_in exocytic vesicle  
located_in membrane  
located_in membrane  
is_active_in plasma membrane  
located_in synaptic vesicle PubMed 

General protein information

Preferred Names
synaptotagmin beta
Names
CG42333-PC
CG42333-PD
Sytbeta-PC
Sytbeta-PD
synaptotagmin V
sytbeta

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    15014695..15064977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144170.2NP_652427.2  synaptotagmin beta, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652427.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AVU5, Q9VUJ6
    Conserved Domains (2) summary
    cd00276
    Location:417545
    C2B_Synaptotagmin; C2 domain second repeat present in Synaptotagmin
    cl14603
    Location:285407
    C2; C2 domain
  2. NM_140477.2NP_648734.1  synaptotagmin beta, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648734.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AVU5, Q9VUJ3
    Related
    FBpp0289127
    Conserved Domains (2) summary
    cd00276
    Location:473601
    C2B_Synaptotagmin; C2 domain second repeat present in Synaptotagmin
    cl14603
    Location:341463
    C2; C2 domain
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