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    SHM1 serine transhydroxymethyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829949, updated on 18-Sep-2024

    Summary

    Official Symbol
    SHM1
    Official Full Name
    serine transhydroxymethyltransferase 1
    Primary source
    TAIR:AT4G37930
    Locus tag
    AT4G37930
    See related
    Araport:AT4G37930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20D10.50; F20D10_50; SERINE HYDROXYMETHYLTRANSFERASE 1; SERINE TRANSHYDROXYMETHYLASE; SERINE TRANSHYDROXYMETHYLTRANSFERASE; serine transhydroxymethyltransferase 1; SHMT1; STM
    Summary
    Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.
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    Genomic context

    See SHM1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    15
    Sequence:
    Chromosome: 4; NC_003075.7 (17831731..17835017, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene endoribonuclease E-like protein Neighboring gene subunit NDH-M of NAD(P)H:plastoquinone dehydrogenase complex Neighboring gene AGAMOUS-like 21 Neighboring gene Rhamnogalacturonate lyase family protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    NM_119954.4

    Gene Ontology Provided by TAIR

    General protein information

    Preferred Names
    serine transhydroxymethyltransferase 1
    NP_195506.1
    • serine transhydroxymethyltransferase 1 (SHM1); FUNCTIONS IN: poly(U) RNA binding, glycine hydroxymethyltransferase activity; INVOLVED IN: in 8 processes; LOCATED IN: in 9 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine hydroxymethyltransferase 2 (TAIR:AT5G26780.1); Has 11621 Blast hits to 11596 proteins in 2825 species: Archae - 258; Bacteria - 6371; Metazoa - 337; Fungi - 287; Plants - 346; Viruses - 6; Other Eukaryotes - 4016 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17831731..17835017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119954.4NP_195506.1  serine transhydroxymethyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195506.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q940M9, Q9SZJ5
      UniProtKB/TrEMBL
      A0A178UYX1, A0A5S9Y0H0, A0A654FWH3
      Conserved Domains (1) summary
      PLN03226
      Location:41517
      PLN03226; serine hydroxymethyltransferase; Provisional
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