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    Eip74EF Ecdysone-induced protein 74EF [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39962, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eip74EFprovided by FlyBase
    Official Full Name
    Ecdysone-induced protein 74EFprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000567
    Locus tag
    Dmel_CG32180
    See related
    AllianceGenome:FB:FBgn0000567
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    3.3; 74EF; CG32180; CG6273; CG6285; Dmel\CG32180; E-74; e74; E74; E74-B; E74A; E74A/B; e74b; e74B; E74B; EcI; ECIP; Eip74; Eip74 A; Eip74A; Eip74E; eip74ef; eip74EF; l(3)24; l(3)neo24; mE74
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including autophagic cell death; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus. Is expressed in adult head; embryonic/larval salivary gland; and organism. Orthologous to human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Eip74EF in Genome Data Viewer
    Location:
    74D4-74E2; 3-45 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17558672..17619325, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17551772..17612425, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cyclin T Neighboring gene small Cajal body-specific RNA : MeU4-A65 Neighboring gene Vacuolar protein sorting 60 Neighboring gene anchor

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    Ecdysone-induced protein 74EF
    Names
    CG32180-PA
    CG32180-PB
    CG32180-PC
    CG32180-PD
    CG32180-PE
    Ecdysone-induced prot 74EF
    Ecdysone-induced-protein 74EF
    Eip74EF-PA
    Eip74EF-PB
    Eip74EF-PC
    Eip74EF-PD
    Eip74EF-PE
    ecdysone E74
    ecdysone induced protein 74EF
    ecdysone inducible protein
    ecdysone-induced protein 74EF
    NP_001246816.1
    • non-AUG (CUG) translation initiation
    NP_730286.3
    • non-AUG (CUG) translation initiation

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17558672..17619325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001014590.2 → NP_001014590.1  Ecdysone-induced protein 74EF, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014590.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V233, P11536, Q86NS8, Q9VVI7
      UniProtKB/TrEMBL
      H1UUR5
      Conserved Domains (1) summary
      pfam00178
      Location:789 → 869
      Ets; Ets-domain
    2. NM_168740.3 → NP_730287.1  Ecdysone-induced protein 74EF, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730287.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P20105, Q9VVI8
      Related
      FBpp0074965
      Conserved Domains (1) summary
      pfam00178
      Location:735 → 815
      Ets; Ets-domain
    3. NM_168739.3 → NP_730286.3  Ecdysone-induced protein 74EF, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730286.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2QCT0
      Related
      FBpp0074966
      Conserved Domains (1) summary
      pfam00178
      Location:774 → 854
      Ets; Ets-domain
    4. NM_001259887.2 → NP_001246816.1  Ecdysone-induced protein 74EF, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NED0
      Conserved Domains (1) summary
      pfam00178
      Location:750 → 830
      Ets; Ets-domain
    5. NM_168741.2 → NP_730288.1  Ecdysone-induced protein 74EF, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730288.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V233, P11536, Q86NS8, Q9VVI7
      UniProtKB/TrEMBL
      H1UUR5
      Related
      FBpp0074967
      Conserved Domains (1) summary
      pfam00178
      Location:789 → 869
      Ets; Ets-domain
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