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R3hdm2 R3H domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362894, updated on 9-Dec-2024

Summary

Official Symbol
R3hdm2provided by RGD
Official Full Name
R3H domain containing 2provided by RGD
Primary source
RGD:1310066
See related
EnsemblRapid:ENSRNOG00000007801 AllianceGenome:RGD:1310066
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310066
Summary
Predicted to enable nucleic acid binding activity. Orthologous to human R3HDM2 (R3H domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Adrenal (RPKM 75.9), Kidney (RPKM 74.3) and 9 other tissues See more
Orthologs
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Genomic context

See R3hdm2 in Genome Data Viewer
Location:
7q22
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (65097685..65225863)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (63212519..63340574)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (70677226..70805255)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093804 Neighboring gene inhibin subunit beta E Neighboring gene inhibin subunit beta C Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 12 Neighboring gene U6 spliceosomal RNA Neighboring gene peptidyl-prolyl cis-trans isomerase D-like Neighboring gene SH3 and cysteine rich domain 3 Neighboring gene NDUFA4, mitochondrial complex associated like 2 Neighboring gene serine hydroxymethyltransferase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding  

General protein information

Preferred Names
R3H domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130557.1NP_001124029.1  R3H domain-containing protein 2

    See identical proteins and their annotated locations for NP_001124029.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473950
    UniProtKB/TrEMBL
    A0A8I5ZKH5, A6HQV5
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam11235
    Location:540734
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:250303
    SUZ; SUZ domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    65097685..65225863
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263810.1XP_063119880.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
  2. XM_063263807.1XP_063119877.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
  3. XM_063263809.1XP_063119879.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
  4. XM_063263808.1XP_063119878.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
  5. XM_039079498.2XP_038935426.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  6. XM_039079496.2XP_038935424.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  7. XM_063263819.1XP_063119889.1  R3H domain-containing protein 2 isoform X18

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  8. XM_039079497.2XP_038935425.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  9. XM_017594931.3XP_017450420.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Related
    ENSRNOP00000073015.1, ENSRNOT00000090001.3
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  10. XM_063263820.1XP_063119890.1  R3H domain-containing protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  11. XM_006241483.5XP_006241545.1  R3H domain-containing protein 2 isoform X21

    See identical proteins and their annotated locations for XP_006241545.1

    UniProtKB/TrEMBL
    A0A8I5ZKH5, A6HQV5
    Related
    ENSRNOP00000078234.1, ENSRNOT00000110189.2
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam11235
    Location:540734
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:250303
    SUZ; SUZ domain
  12. XM_063263824.1XP_063119894.1  R3H domain-containing protein 2 isoform X24

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  13. XM_063263815.1XP_063119885.1  R3H domain-containing protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A8I5ZLX2
    Related
    ENSRNOP00000078773.1, ENSRNOT00000107753.2
  14. XM_063263821.1XP_063119891.1  R3H domain-containing protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  15. XM_008765413.2XP_008763635.1  R3H domain-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_008763635.1

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  16. XM_063263817.1XP_063119887.1  R3H domain-containing protein 2 isoform X15

    UniProtKB/TrEMBL
    A0A0G2K4E8, G3V9G7
    Related
    ENSRNOP00000046983.3, ENSRNOT00000045964.6
  17. XM_063263811.1XP_063119881.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
  18. XM_039079499.2XP_038935427.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  19. XM_039079500.2XP_038935428.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  20. XM_063263812.1XP_063119882.1  R3H domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A0G2K4E8
  21. XM_039079511.2XP_038935439.2  R3H domain-containing protein 2 isoform X28

  22. XM_063263825.1XP_063119895.1  R3H domain-containing protein 2 isoform X26

  23. XM_063263814.1XP_063119884.1  R3H domain-containing protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A0G2K4E8
  24. XM_063263806.1XP_063119876.1  R3H domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K4E8
  25. XM_063263813.1XP_063119883.1  R3H domain-containing protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  26. XM_039079506.2XP_038935434.2  R3H domain-containing protein 2 isoform X13

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  27. XM_039079501.2XP_038935429.2  R3H domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  28. XM_039079504.2XP_038935432.2  R3H domain-containing protein 2 isoform X8

    UniProtKB/TrEMBL
    A0A0G2K4E8
  29. XM_063263822.1XP_063119892.1  R3H domain-containing protein 2 isoform X22

    UniProtKB/TrEMBL
    A0A0G2K4E8
  30. XM_063263818.1XP_063119888.1  R3H domain-containing protein 2 isoform X17

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  31. XM_017594936.3XP_017450425.2  R3H domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K4E8
  32. XM_039079507.2XP_038935435.2  R3H domain-containing protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  33. XM_017594940.3XP_017450429.2  R3H domain-containing protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  34. XM_063263823.1XP_063119893.1  R3H domain-containing protein 2 isoform X23

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  35. XM_039079502.2XP_038935430.2  R3H domain-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8I5ZKH5
  36. XM_039079508.2XP_038935436.2  R3H domain-containing protein 2 isoform X16

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  37. XM_039079505.2XP_038935433.2  R3H domain-containing protein 2 isoform X11

    UniProtKB/TrEMBL
    A0A0G2K4E8
  38. XM_017594943.3XP_017450432.2  R3H domain-containing protein 2 isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  39. XM_017594935.3XP_017450424.1  R3H domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  40. XM_063263816.1XP_063119886.1  R3H domain-containing protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A8I5ZLX2
  41. XM_006241472.3XP_006241534.1  R3H domain-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006241534.1

    UniProtKB/TrEMBL
    A0A0G2K4E8
    Related
    ENSRNOP00000099915.1, ENSRNOT00000125954.1
    Conserved Domains (3) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:468801
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:250302
    SUZ; SUZ domain
  42. XM_039079509.1XP_038935437.1  R3H domain-containing protein 2 isoform X25

    UniProtKB/TrEMBL
    A0A8I5ZLX2
    Conserved Domains (2) summary
    cd02642
    Location:168229
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:427717
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
  43. XM_039079510.1XP_038935438.1  R3H domain-containing protein 2 isoform X27

    Conserved Domains (2) summary
    pfam09606
    Location:198531
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:232
    SUZ; SUZ domain
  44. XM_063263826.1XP_063119896.1  R3H domain-containing protein 2 isoform X29

  45. XM_063263828.1XP_063119898.1  R3H domain-containing protein 2 isoform X30

  46. XM_063263827.1XP_063119897.1  R3H domain-containing protein 2 isoform X29

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