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ncx-3 Calx-beta domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177963, updated on 9-Dec-2024

Summary

Official Symbol
ncx-3
Official Full Name
Calx-beta domain-containing protein
Primary source
WormBase:WBGene00003568
Locus tag
CELE_ZC168.1
See related
AllianceGenome:WB:WBGene00003568
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium:sodium antiporter activity; calmodulin binding activity; and metal ion binding activity. Predicted to be involved in metal ion transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in dorsal nerve cord; head neurons; phasmid neurons; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See ncx-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (10716648..10721755)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene MARVEL domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene Globin domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Origin recognition complex subunit 5 C-terminal domain-containing protein

Interactions

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables antiporter activity  
enables calcium:sodium antiporter activity  
enables calcium:sodium antiporter activity  
enables calmodulin binding  
enables metal ion binding  
Process Evidence Code Pubs
involved_in calcium ion import across plasma membrane  
involved_in calcium ion transport  
involved_in cell communication  
involved_in sodium ion transmembrane transport  
involved_in sodium ion transport  
involved_in transmembrane transport  
Component Evidence Code Pubs
is_active_in axon  
located_in membrane  
located_in plasma membrane  
is_active_in postsynapse  
is_active_in sarcolemma  

General protein information

Preferred Names
Calx-beta domain-containing protein
NP_501984.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10716648..10721755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069583.4NP_501984.2  Calx-beta domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501984.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECW0
    Conserved Domains (5) summary
    smart00237
    Location:470559
    Calx_beta; Domains in Na-Ca exchangers and integrin-beta4
    TIGR00845
    Location:8825
    caca; sodium/calcium exchanger 1
    pfam01699
    Location:659822
    Na_Ca_ex; Sodium/calcium exchanger protein
    pfam05823
    Location:216297
    Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)
    cl02522
    Location:348435
    Calx-beta; Calx-beta domain
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