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Items: 1 to 20 of 227

1.
Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance
Yiting Mao, Yicong Meng, Kexin Zou, Ningxin Qin, Yinyu Wang, Jing Yan, PinJia Chen, Yi Cheng, Weihui Shi, Chengliang Zhou, Huixi Chen, Jianzhong Sheng, Xinmei Liu, Jiexue Pan, Hefeng Huang
J Neuroinflammation. 2024; 21: 249. Published online 2024 Oct 4. doi: 10.1186/s12974-024-03248-8
PMCID:
PMC11453047
AbstractArticlePDF–8.9M
2.
Mouse monocytes express CD127 by immune cells, not LPS
Reza Yazdani, Mozhde Askari, Amir Moghadam Ahmadi, Gholamreza Azizi, Bogoljub Ciric, Alexandra Boehm, Guang-Xian Zhang, Abdolmohamad Rostami
Front Immunol. 2024; 15: 1356004. Published online 2024 Sep 12. doi: 10.3389/fimmu.2024.1356004
PMCID:
PMC11424446
AbstractArticlePDF–1.6M
3.
IL-7 receptor signaling drives human B-cell progenitor differentiation and expansion
Fabian M. P. Kaiser, Iga Janowska, Roberta Menafra, Melanie de Gier, Jakov Korzhenevich, Ingrid Pico-Knijnenburg, Indu Khatri, Ansgar Schulz, Taco W. Kuijpers, Arjan C. Lankester, Lukas Konstantinidis, Miriam Erlacher, Susan Kloet, Pauline A. van Schouwenburg, Marta Rizzi, Mirjam van der Burg
Blood. 2023 Sep 28; 142(13): 1113–1130. Published online 2023 Jun 29. doi: 10.1182/blood.2023019721
PMCID:
PMC10644098
AbstractArticle
4.
Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
Ana C.F. Ferreira, Aydan C.H. Szeto, Paula A. Clark, Alastair Crisp, Patrycja Kozik, Helen E. Jolin, Andrew N.J. McKenzie
Immunity. 2023 Jul 11; 56(7): 1468–1484.e7. doi: 10.1016/j.immuni.2023.05.010
PMCID:
PMC10501989
AbstractArticle
5.
Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation
Joseph Roberts, Anne Chevalier, Heike C. Hawerkamp, Aoife Yeow, Laura Matarazzo, Christian Schwartz, Emily Hams, Padraic G. Fallon
J Immunol. 2023 Aug 15; 211(4): 626–632. Published online 2023 Jun 30. doi: 10.4049/jimmunol.2200896
PMCID:
PMC10404816
AbstractArticlePDF–1.3M
6.
Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms
Ashley Hernandez-Gutierrez, Sonoor Majid, Adam Eberle, Ashley Choi, Parand Sorkhdini, Dongqin Yang, Alina Xiaoyu Yang, Carmelissa Norbrun, Chuan Hua He, Chang-min Lee, Chun Geun Lee, Jack A. Elias, Yang Zhou
J Clin Invest. 2023 Aug 1; 133(15): e169583. Published online 2023 Aug 1. doi: 10.1172/JCI169583
PMCID:
PMC10378191
AbstractArticlePDF–7.3M
7.
In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells
Joo-Young Park, Hee Yeun Won, Devon T. DiPalma, Hye Kyung Kim, Tae-Hyoun Kim, Can Li, Noriko Sato, Changwan Hong, Ninan Abraham, Ronald E. Gress, Jung-Hyun Park
Cell Rep. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110219. doi: 10.1016/j.celrep.2021.110219
PMCID:
PMC10292121
AbstractArticlePDF–2.8M
8.
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
Oksana Tsyklauri, Tereza Chadimova, Veronika Niederlova, Jirina Kovarova, Juraj Michalik, Iva Malatova, Sarka Janusova, Olha Ivashchenko, Helene Rossez, Ales Drobek, Hana Vecerova, Virginie Galati, Marek Kovar, Ondrej Stepanek
eLife. 2023; 12: e79342. Published online 2023 Jan 27. doi: 10.7554/eLife.79342
PMCID:
PMC9977273
AbstractArticlePDF–3.2M
9.
Spleen tyrosine kinase mediates the γδTCR signaling required for γδT cell commitment and γδT17 differentiation
Ryunosuke Muro, Tomoya Narita, Takeshi Nitta, Hiroshi Takayanagi
Front Immunol. 2022; 13: 1045881. Published online 2023 Jan 12. doi: 10.3389/fimmu.2022.1045881
PMCID:
PMC9878111
AbstractArticlePDF–3.6M
10.
SLC7A8 is a key amino acids supplier for the metabolic programs that sustain homeostasis and activation of type 2 innate lymphoid cells
Santosh K. Panda, Do-Hyun Kim, Pritesh Desai, Patrick F. Rodrigues, Raki Sudan, Susan Gilfillan, Marina Cella, Steven J. Van Dyken, Marco Colonna
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2215528119. Published online 2022 Nov 7. doi: 10.1073/pnas.2215528119
PMCID:
PMC9674248
AbstractArticlePDF–1.8M
11.
Whole-genome profiling of DNA methylation and hydroxymethylation identifies distinct regulatory programs among innate lymphocytes
Vincent Peng, Xiaoyun Xing, Jennifer K Bando, Tihana Trsan, Blanda Di Luccia, Patrick L Collins, Daofeng Li, Wei-Le Wang, Hyung Joo Lee, Eugene M Oltz, Ting Wang, Marco Colonna
Nat Immunol. Author manuscript; available in PMC 2022 Sep 24.
Published in final edited form as: Nat Immunol. 2022 Apr; 23(4): 619–631. Published online 2022 Mar 24. doi: 10.1038/s41590-022-01164-8
PMCID:
PMC8989654
AbstractArticlePDF–5.1M
12.
IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells
Atesh K. Worthington, Taylor Cool, Donna M. Poscablo, Adeel Hussaini, Anna E. Beaudin, E. Camilla Forsberg
Development. 2022 Apr 15; 149(8): dev200139. Published online 2022 Jan 24. doi: 10.1242/dev.200139
PMCID:
PMC8917444
AbstractArticle
13.
Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation
Kelly M Cautivo, Peri R Matatia, Carlos O Lizama, Nicholas M. Mroz, Madelene W Dahlgren, Xiaofei Yu, Julia Sbierski-Kind, Marcela T Taruselli, Jeremy F Brooks, Adam Wade-Vallance, Sofia E. Caryotakis, Anthony A Chang, Hong-Erh Liang, Julie Zikherman, Richard M Locksley, Ari B Molofsky
Immunity. Author manuscript; available in PMC 2023 Feb 8.
Published in final edited form as: Immunity. 2022 Feb 8; 55(2): 254–271.e7. doi: 10.1016/j.immuni.2021.12.014
PMCID:
PMC8852844
AbstractArticlePDF–5.1M
14.
Btn2a2 Regulates ILC2–T Cell Cross Talk in Type 2 Immune Responses
Michael Frech, Yasunori Omata, Angelika Schmalzl, Stefan Wirtz, Leila Taher, Georg Schett, Mario M. Zaiss, Kerstin Sarter
Front Immunol. 2022; 13: 757436. Published online 2022 Jan 25. doi: 10.3389/fimmu.2022.757436
PMCID:
PMC8821520
AbstractArticlePDF–5.0M
15.
Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice
Kerri R. Thomas, Eric J. Allenspach, Nathan D. Camp, Michelle N. Wray-Dutra, Socheath Khim, Anna Zielinska-Kwiatkowska, Andrew E. Timms, Joseph P. Loftus, H. Denny Liggitt, Katia Georgopoulos, Sarah K. Tasian, Richard G. James, David J. Rawlings
Leukemia. Author manuscript; available in PMC 2022 Jan 6.
Published in final edited form as: Leukemia. 2022 Jan; 36(1): 42–57. Published online 2021 Jun 30. doi: 10.1038/s41375-021-01326-x
PMCID:
PMC8716641
AbstractArticlePDF–2.9M
16.
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia
Afonso R. M. Almeida, João L. Neto, Ana Cachucho, Mayara Euzébio, Xiangyu Meng, Rathana Kim, Marta B. Fernandes, Beatriz Raposo, Mariana L. Oliveira, Daniel Ribeiro, Rita Fragoso, Priscila P. Zenatti, Tiago Soares, Mafalda R. de Matos, Juliana Ronchi Corrêa, Mafalda Duque, Kathryn G. Roberts, Zhaohui Gu, Chunxu Qu, Clara Pereira, Susan Pyne, Nigel J. Pyne, Vasco M. Barreto, Isabelle Bernard-Pierrot, Emannuelle Clappier, Charles G. Mullighan, Ana R. Grosso, J. Andrés Yunes, João T. Barata
Nat Commun. 2021; 12: 7268. Published online 2021 Dec 14. doi: 10.1038/s41467-021-27197-5
PMCID:
PMC8671594
AbstractArticlePDF–5.1M
17.
Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
Keiko Sakamoto, Seon-Pil Jin, Shubham Goel, Jay-Hyun Jo, Benjamin Voisin, Doyoung Kim, Vinod Nadella, Hai Liang, Tetsuro Kobayashi, Xin Huang, Clay Deming, Keisuke Horiuchi, Julia A. Segre, Heidi H. Kong, Keisuke Nagao
Immunity. Author manuscript; available in PMC 2022 Oct 12.
Published in final edited form as: Immunity. 2021 Oct 12; 54(10): 2321–2337.e10. Published online 2021 Sep 27. doi: 10.1016/j.immuni.2021.09.001
PMCID:
PMC8516731
AbstractArticlePDF–4.0M
18.
Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma
Ana Silva, Afonso R. M. Almeida, Ana Cachucho, João L. Neto, Sofie Demeyer, Mafalda de Matos, Thea Hogan, Yunlei Li, Jules Meijerink, Jan Cools, Ana Rita Grosso, Benedict Seddon, João T. Barata
Blood. 2021 Sep 23; 138(12): 1040–1052. Prepublished online 2021 May 10. doi: 10.1182/blood.2019000553
Correction in:
Blood. 2024 May 16; 143(20): 2108–2110.
PMCID:
PMC8462360
AbstractArticle
19.
Liver X receptor β is required for the survival of single-positive thymocytes by regulating IL-7Rα expression
Huang Huang, Xiaoping Wu, Dongwei Meng, Yizhou Feng, Lan Zhou, Zhenyu Liu, Shupei Tang, Xueqin Li, Yi Cao, Haiyang He, Zhunyi Xie, Jingbo Zhang, Yongwen Chen, Tingting Zhao, Yuzhang Wu, Xinyuan Zhou
Cell Mol Immunol. 2021 Aug; 18(8): 1969–1980. Published online 2020 Sep 22. doi: 10.1038/s41423-020-00546-y
PMCID:
PMC8322414
AbstractArticlePDF–2.2M
20.
Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity
Laura Mathä, Mónica Romera-Hernández, Catherine A. Steer, Yi Han Yin, Mona Orangi, Hanjoo Shim, ChihKai Chang, Fabio M. Rossi, Fumio Takei
Front Immunol. 2021; 12: 679509. Published online 2021 Jul 9. doi: 10.3389/fimmu.2021.679509
PMCID:
PMC8299566
AbstractArticlePDF–5.3M

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