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Select item 85638811.

Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat brain partly via affecting membrane expression of ezrin/radixin/moesin proteins

Tong Wu, Yun Sheng, Yuan-yuan Qin, Wei-min Kong, Meng-meng Jin, Han-yu Yang, Xiao-ke Zheng, Chang Dai, Ming Liu, Xiao-dong Liu, Li Liu

Acta Pharmacol Sin. 2021 Nov; 42(11): 1942–1950. Published online 2021 Feb 8. doi: 10.1038/s41401-020-00602-3

PMCID:: PMC8563881

Abstract Article PDF–1.7M

Select item 82770732.

Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters

Samit Ganguly, David Finkelstein, Timothy I. Shaw, Ryan D. Michalek, Kimberly M. Zorn, Sean Ekins, Kazuto Yasuda, Yu Fukuda, John D. Schuetz, Kamalika Mukherjee, Erin G. Schuetz

PLoS One. 2021; 16(7): e0253852. Published online 2021 Jul 13. doi: 10.1371/journal.pone.0253852

PMCID:: PMC8277073

Abstract Article PDF–3.6M

Select item 80125963.

Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2

Tetsuya Taniguchi, Koichi Omura, Keisuke Motoki, Miku Sakai, Noriko Chikamatsu, Naoki Ashizawa, Tappei Takada, Takashi Iwanaga

Sci Rep. 2021; 11: 7232. Published online 2021 Mar 31. doi: 10.1038/s41598-021-86662-9

PMCID:: PMC8012596

Abstract Article PDF–1.6M

Select item 77803014.

Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats

Alaa M. Hammad, Fawaz Alasmari, Youssef Sari, F. Scott Hall, Amit K. Tiwari

Mol Neurobiol. Author manuscript; available in PMC 2021 Jan 4.

Published in final edited form as: Mol Neurobiol. 2019 Mar; 56(3): 1921–1932. Published online 2018 Jul 6. doi: 10.1007/s12035-018-1153-2

PMCID:: PMC7780301

Abstract Article PDF–913K

Select item 63790615.

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Ioannis Manolaridis, Scott M. Jackson, Nicholas M. I. Taylor, Julia Kowal, Henning Stahlberg, Kaspar P. Locher

Nature. Author manuscript; available in PMC 2019 May 7.

Published in final edited form as: Nature. 2018 Nov; 563(7731): 426–430. Published online 2018 Nov 7. doi: 10.1038/s41586-018-0680-3

PMCID:: PMC6379061

Abstract Article PDF–4.4M

Select item 54977566.

Localization of the Placental BCRP/ABCG2 Transporter to Lipid Rafts: Role for Cholesterol in Mediating Efflux Activity

John T. Szilagyi, Anna M. Vetrano, Jeffrey D. Laskin, Lauren M. Aleksunes

Placenta. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Placenta. 2017 Jul; 55: 29–36. Published online 2017 Apr 12. doi: 10.1016/j.placenta.2017.04.006

PMCID:: PMC5497756

Abstract Article PDF–1.3M

Select item 49733787.

Unconjugated bilirubin elevation impairs the function and expression of breast cancer resistance protein (BCRP) at the blood-brain barrier in bile duct-ligated rats

Ping Xu, Zhao-li Ling, Ji Zhang, Ying Li, Nan Shu, Ze-yu Zhong, Yang Chen, Xin-yu Di, Zhong-jian Wang, Li Liu, Xiao-dong Liu

Acta Pharmacol Sin. 2016 Aug; 37(8): 1129–1140. Published online 2016 May 16. doi: 10.1038/aps.2016.25

PMCID:: PMC4973378

Abstract Article PDF–2.5M

Select item 46950208.

Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft model

Cuiping Yang, Fei Xiong, Jun Dou, Jun Xue, Xi Zhan, Fangfang Shi, Miao Li, Songyan Wu, Shouhua Luo, Tianzhu Zhang, Yu Zhang, Ji Ming, Ning Gu

Oncotarget. 2015 Sep 29; 6(29): 27714–27724. Published online 2015 Jul 15. doi: 10.18632/oncotarget.4663

PMCID:: PMC4695020

Abstract Article PDF–4.8M

Select item 44304119.

Toxicological Significance of Renal Bcrp: Another Potential Transporter in the Elimination of Mercuric Ions from Proximal Tubular Cells

Christy C. Bridges, Rudolfs K. Zalups, Lucy Joshee

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2015 Jun 1; 285(2): 110–117. Published online 2015 Apr 11. doi: 10.1016/j.taap.2015.03.027

PMCID:: PMC4430411

Abstract Article PDF–1.5M

Select item 415552510.

Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes

Dan Xu, Feng Li, Mian Zhang, Ji Zhang, Can Liu, Meng-yue Hu, Ze-yu Zhong, Ling-ling Jia, Da-wei Wang, Jie Wu, Li Liu, Xiao-dong Liu

Acta Pharmacol Sin. 2014 Sep; 35(9): 1215–1225. Published online 2014 Aug 25. doi: 10.1038/aps.2014.39

PMCID:: PMC4155525

Abstract Article PDF–584K

Select item 385854711.

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients

Marc Delord, Philippe Rousselot, Jean Michel Cayuela, François Sigaux, Joëlle Guilhot, Claude Preudhomme, François Guilhot, Pascale Loiseau, Emmanuel Raffoux, Daniela Geromin, Emmanuelle Génin, Fabien Calvo, Heriberto Bruzzoni-Giovanelli

Oncotarget. 2013 Oct; 4(10): 1582–1591. Published online 2013 Jul 18. doi: 10.18632/oncotarget.1050

PMCID:: PMC3858547

Abstract Article PDF–172K

Select item 379320312.

Sex and age interaction with genetic association of atherogenic uric acid concentrations

Anita Brandstätter, Claudia Lamina, Stefan Kiechl, Steven C. Hunt, Stefan Coassin, Bernhard Paulweber, Felix Kramer, Monika Summerer, Johann Willeit, Lyudmyla Kedenko, Ted D. Adams, Florian Kronenberg

Atherosclerosis. Author manuscript; available in PMC 2013 Oct 9.

Published in final edited form as: Atherosclerosis. 2010 Jun; 210(2): 474–478. Published online 2009 Dec 16. doi: 10.1016/j.atherosclerosis.2009.12.013

PMCID:: PMC3793203

Abstract Article PDF–1.0M

Select item 370900713.

METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS

Mitchell R. McGill, Hartmut Jaeschke

Pharm Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Pharm Res. 2013 Sep; 30(9): 2174–2187. Published online 2013 Mar 6. doi: 10.1007/s11095-013-1007-6

PMCID:: PMC3709007

Abstract Article PDF–2.0M

Select item 362575214.

Breast cancer resistance protein regulates apical ectoplasmic specialization dynamics stage specifically in the rat testis

Xiaojing Qian, Dolores D. Mruk, Elissa W. P. Wong, C. Yan Cheng

Am J Physiol Endocrinol Metab. 2013 Apr 1; 304(7): E757–E769. Published online 2013 Feb 12. doi: 10.1152/ajpendo.00645.2012

PMCID:: PMC3625752

Abstract Article

Select item 343244915.

A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk

Daniele Campa, Katja Butterbach, Susan L Slager, Christine F Skibola, Silvia de Sanjosé, Yolanda Benavente, Nikolaus Becker, Lenka Foretova, Marc Maynadie, Pierluigi Cocco, Anthony Staines, Rudolf Kaaks, Paolo Boffetta, Paul Brennan, Lucia Conde, Paige M Bracci, Neil E Caporaso, Sara S Strom, Nicola J Camp, James R Cerhan, GEC Consortium, Federico Canzian, Alexandra Nieters

Int J Cancer. Author manuscript; available in PMC 2013 Aug 15.

Published in final edited form as: Int J Cancer. 2012 Aug 15; 131(4): 803–812. Published online 2011 Nov 28. doi: 10.1002/ijc.26436