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PREDICTED: Homo sapiens ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 (ST8SIA6), transcript variant X3, mRNA

NCBI Reference Sequence: XM_024447977.2

FASTA Graphics 

LOCUS       XM_024447977            6596 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ST8 alpha-N-acetyl-neuraminide
            alpha-2,8-sialyltransferase 6 (ST8SIA6), transcript variant X3,
            mRNA.
ACCESSION   XM_024447977
VERSION     XM_024447977.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024447977.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6596
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..6596
                     /gene="ST8SIA6"
                     /gene_synonym="SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI;
                     ST8SiaVI"
                     /note="ST8 alpha-N-acetyl-neuraminide
                     alpha-2,8-sialyltransferase 6; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1 EST,
                     50 long SRA reads, 1 Protein, and 97% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     3 samples with support for all annotated introns"
                     /db_xref="GeneID:338596"
                     /db_xref="HGNC:HGNC:23317"
                     /db_xref="MIM:610139"
     CDS             396..1139
                     /gene="ST8SIA6"
                     /gene_synonym="SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI;
                     ST8SiaVI"
                     /codon_start=1
                     /product="alpha-2,8-sialyltransferase 8F isoform X2"
                     /protein_id="XP_024303745.1"
                     /db_xref="GeneID:338596"
                     /db_xref="HGNC:HGNC:23317"
                     /db_xref="MIM:610139"
                     /translation="MSYEVESKKEIPIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
                     NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNLKEKKAL
                     FLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKYLKDLALFW
                     RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDNKLPKHGF
                     HQMPKEYSQILQLHMKGILKLQFSKCEVA"
ORIGIN      
        1 tcaaggggga tcctccagca gctgcatttg aaaaacgggt gctgagtttt cctctcgaca
       61 atggtgtgtt gaaagcaccc ccgcccccga ccccgccacc tttggagaga agcagctcag
      121 cctgtcttta tggagggatt tgcacatatc tgaatgagaa gtcgctccaa ctgacggaga
      181 aatgcaaaaa tctgcaatat ggcattgagt ctttctctaa caaaacgaaa gggtattcag
      241 agaacgacta ccttcagatt atcacagata tacagagttg tccatggaaa cggcaagcag
      301 aagaatatgc aaattttaga gccaaacttg cttcctgctg tgatgctgtt caaaactttg
      361 ttgtttctca gaataacact ccagttggga ctaatatgag ttacgaggtg gaaagcaaaa
      421 aagaaatccc aattaagaag aacatttttc atatgtttcc agtgtcccag ccttttgtgg
      481 actaccctta taatcagtgt gcagtggtcg gaaatggggg aattctgaat aagtctctct
      541 gtggaactga aatagataaa tccgacttcg tttttaggtg taacctaccc ccaaccacag
      601 gagatgttag taaagatgtt ggcagtaaaa caaatcttgt gactataaat ccaagcatca
      661 taactctgaa atatgggaac ttaaaggaaa aaaaagccct atttctggag gacattgcaa
      721 cctatggaga tgcatttttt cttctgccag cattttcctt cagggccaac acgggtacct
      781 ctttcaaagt atactacacg ctcgaagagt ctaaagcaag acaaaaggtt ctatttttcc
      841 atcccaagta cctgaaagat ctggcccttt tctggagaac taaaggtgtg actgcatacc
      901 gcttgtccac cggcttgatg atcacaagtg ttgcagtgga actgtgtaaa aatgtgaagc
      961 tgtatggatt ctggcccttc tctaaaactg tagaagacat acctgtcagc catcactatt
     1021 atgacaacaa gctacctaaa catggtttcc atcagatgcc caaagaatac agccagatcc
     1081 tccaacttca catgaaagga atcctcaaac tgcaatttag caaatgtgaa gtcgcctaaa
     1141 caaagtatct taaaatggga ataattttaa tataatgcag taggtgatta acaatgtctc
     1201 caaacaccaa aggaggtggc taaagagtat tttgagatga gccccaaaat ttggtttgac
     1261 caaagcttcc ccactcattt tgcaatgatg gcaagtcatt caatccttct catcttcatt
     1321 ttttctcctt ataacatgga caccatatct gactcataca aatttttata atttatgaaa
     1381 attattggca tggcctttgg tgtgaggtag ggactcaaag aatatttctt tcttactatt
     1441 tataccagcc atctccacct tcaccagacc gataataaaa gcatgctttc ttggagatct
     1501 cttctaaaga gaatagctgc attaccagta tccattggat ttctttctgt ggcaggtctc
     1561 tatcaataat atccttccca tttttctgtc tcaaagactg catgcaagaa aattatatac
     1621 ttaagcaaaa agttcttgat cattcgggaa tgaaattctt ctctgagtat ggcagtatgc
     1681 ctgcttctga ttaaattcac ttttaatagt agctgtgatg atattttggt tgaatttaag
     1741 ccatttattt tcctcttatg tctacatttc ttcatcactt aataatttta ttttaacttc
     1801 ctgcctcatt cttacacttt tttctctctc acttatacga tatacttcaa ggacgtgaac
     1861 agttacaata cccagtcttt cttacctgtt gtcttgcctg tggggtcact cactcaattt
     1921 tattttaaaa ttactgaata actacttcat gccaggccct gcaccaggct ctgtgagagg
     1981 acaagaagga ttattgcctc ttgtaggaga aaacagatgt gcatatcatt aattatgatg
     2041 gggtatgata agtattacaa tgacaaaagc tatgaataaa gtgctacaag gaacagaagc
     2101 agggataatt aaatccattt cagtggaatc tatttcaatg tacaatagtc tcccctaatc
     2161 tgcagatatg ggaagacccc ctgtggatgc ctgaaaccat tgatgatatt agaaatatgt
     2221 aattgattag taaaagtaac aaaatatact gaaataatta aatatacaat gtggggactt
     2281 tatatgctat tttaataaaa cttacatata gttaggacat ttagagctta cttttttttc
     2341 ccatataata tcctatctta aaaatttttc tttagaacat caaaacagaa tctctagtat
     2401 cactgatatg gatttcagaa atattccaaa tggtgtgaga tcaaacagca tagtgatacc
     2461 catgttccag taaaagctta ggagaaaaag aatgtttgcg ggttttcttt tgtggagaaa
     2521 attgtagaca tttccaagtt aacacatctg aagtttctgg ttcgacatct gtgttgccat
     2581 cctaaaagca cgtgtgaaat tttacaacaa tcctacctag attcacgtta gccaaaaatc
     2641 tttggctaaa cagacacccc gagatttcat aaagtgtgtt atagtcagaa ttggtggtaa
     2701 ttaatctaca aatctgcaaa atagtgttca tagtttttct ttttattttg atcttggtga
     2761 aaaacttgca gtaactcacc attacagagc gacaagaact gtgacgcatg ttttatgatt
     2821 tacatagctg atgtggtgta ttatcgatat ccataatctg tcatatttag acacattcat
     2881 tgtgacacat ataacatgtg cattcttttt atctttttct caagtgggtc tatagttgtg
     2941 atttcacagc agattggggt tgttggccat tgtttgaagc tctcctactc tctttctagc
     3001 atagtcagtg tgttgcagag aactaaaggg agtaaaagac acagtgcctc attgaatcct
     3061 aacattttct tcctggtagg gcatatatcc caccttccat atatcctgct gtgaggtgcc
     3121 aataatgttc ttttgttcca aaacagaaca ttacttagaa ctttctaaaa tatgatagaa
     3181 catgaatgtt tacaatacag catgtcagct atgtaaactg taaaacgtaa gtcacagttc
     3241 tttttgttct gtattggtga atcattgcaa atttttcacc aagtgcaaaa caaaaagaaa
     3301 aactataaac tccatcttgt agatttgtag attcgccaca accaagtctg actgtgacac
     3361 tcccaagaaa tctgtatgta atcagcattg cttaaatatt gttagatcta atgtgatctt
     3421 ctgctcttaa aactcaagta catctaaggg cattgagaat ggaaagtctg agttctggta
     3481 ctagacaaga gcagcccttt aggccaggcg caatggctca cacctgtaat cccagcactt
     3541 tgggaggcca aggtgggtgg gtcacttgag gccaggagtt tgagactagc ctgggcaaca
     3601 tagtgagtac ccttctctac aaaaaacaaa aaaattagct gagcatagtg gcgtgcacct
     3661 gtggtcccag ctacttggga ggctaaggag ggaggttcac tggagcccag gaggtagagg
     3721 ctgcagtgag ctgtgatctt accactgcat tctagcctgt gtgacagagt gagaccctgt
     3781 ctcaaaaaag aaaaaaaaaa agtagccctt tagttaggat tctagctcat aacgctgcat
     3841 actaccagtt tctaagagaa atactagctt gctggattct attttccact tgttgttcag
     3901 cctcattgag caatgaaaca gaataacaag attccaatat aattttcagc caaatccaaa
     3961 ggcaaggcag aaatattcat ttaagtatat agtccatagt actctgtggt ccctgcaaag
     4021 ggcttcatga tcaattgcat agtgttaatt tttgcgcagt gtaataatcc tcgaacatcc
     4081 ttgaagtctc tggtgctttt cccttggaac aaaaggcaat gacaaataga tcatggcttt
     4141 cactaaagga tatttccttc ttcatgtaag tcctaaccca gtaactgcgt gggctctcag
     4201 ccaggtaatc agtcaaaaag tctttttttg aggactctct gtagaataca gaattaagca
     4261 gcaaatcaga cctgtgtttg cctaaatttt tccttgctta taaaaaattt accagctaag
     4321 tattatgtaa tgtcaagtac cgtaaatcac tccatgaatt aggaagcttt gggaaaagtg
     4381 gaaaattttg tggaaaacag gtccactaac atcctaaaca gctactgcag aagtatagtt
     4441 aagatgtgat atataatata ttgtgatctt caagacattt tatttatcta acatgacatg
     4501 gaaacacatt attatgccat taaaaattga aggcattgta ggaattcatc tgatatatct
     4561 gatgcacttg atctgataaa tccacttgag gctgctagga gtgttgaaga tttcctattt
     4621 acatgtggct tcagaaggct gatcccatag cgaggaacag tgtcaccagt accctcctga
     4681 gagtggaaag gcaagaatat ttctcatggt ctttcttatt ttgggtcatc actcttccag
     4741 aagcattctt ctttttataa aaaaaatgtg ggtgatatat gataaagatg cgctacttat
     4801 gtaatggaga cagggcaaac tctttagcag ataatattga aacattggct cactctatgg
     4861 agaaaaataa atgcctacat tgcaccatat aaaaagttgg gctccagagg gatgaaaacg
     4921 atggattaaa aagaaaactt taaagctcat agaagaaaat gtaggagaat tatgtttgag
     4981 atacaggtga ggaactgtac ttcttcaaca tgacccaaaa atatcttttt aaatagttgg
     5041 gttaagaaag gatggctatg actgtattaa aatgaaagag ttctagtcag tgaatgacac
     5101 cttaaagtta ataggctggg gacagactga aatagctttt agtaatgcat aaaattaatg
     5161 acattaatag agagacattc caaggaattg taaatcaaca agtaaaagac aggaaactca
     5221 atataaaaat gaacaaaaga taagaatgtg atttacaaag gggaaagctg agtagctaat
     5281 aagaatagga agtgatactc aaatttacca gtaacctgag aaatgcaaat gaaagtgaga
     5341 tactacatcc attgcattgg taaaaatgag taaggtcatt aacttcaagt gtggaagtat
     5401 aagctgattg aatcattttg gaaagcaacc taggagtact gagttagtaa aattcatcat
     5461 atgtctgtcc tatagtccag taattgcact tttgcatata cagccaagag gacctgttct
     5521 gatccacaca aaaaaacaag tattaaggta tttattccat tatggtttgc ggtagtaagt
     5581 agacaaattg gactcacaga tatctgtctc ttcggaagtc agtgaactaa cttgactgga
     5641 tccatagtgt ggaatatgat acagcagtta gaagcaactt actggacata tatacagaaa
     5701 taagggtatg tcctttaaat ttagcataaa gggaaaacaa aagctttagc acaatgccat
     5761 ttaattactt taaagcgtat gcatgcatac atacaaacat attcaaggct acgtgtcaaa
     5821 tacaagaagg gtacccatta agaagagggt aatcggagtg ggtttaggga taaagaagaa
     5881 aaatatacat gttattatat ttaatacagc aagcctttga catatatatt cttatactca
     5941 catatgatat tcttactact acataaataa atatagaagc tgactcaaaa ttgtaagtaa
     6001 cttatataag gttgcattat atataagagc agagctagta ttcaactcat atgtctgact
     6061 ctaaagccaa tattatttcc attatgcaat tataaaatga aaagaaaaat cagtattatc
     6121 ccatgtcatt gacatgtaat aaatggcaca tatttatgta catgcatata cccatgaaac
     6181 cgtctctcca attaagacaa tgtatatatt cattacccca aaatgttttc ttgtgctact
     6241 ttgtaatccc tccctcttct tcctccctgt ccatcccacc ctcgtcccca gaaaattcct
     6301 aatctgtttt tctatagaca tttacatttt tacactatag actgtttaca ttttttagaa
     6361 ttttatataa atggaatctt actgtctgta ctcatttctt gtcttgcact tttgctcgac
     6421 ataataatat taaaactcat tcatgttgat tgtgtatctg tagtttatgc ctttatttac
     6481 tgagtagaat tatgttatat ggatggacca cagttggctt atctgctcat ttgttgatga
     6541 acattttact atctcctggt tttggctatt acaaataaag gtatcatgaa cattaa
//
396..1139
/gene="ST8SIA6"
/gene_synonym="SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI;
ST8SiaVI"
/codon_start=1
/product="alpha-2,8-sialyltransferase 8F isoform X2"
/protein_id="XP_024303745.1"
/db_xref="GeneID:338596"
/db_xref="HGNC:HGNC:23317"
/db_xref="MIM:610139"
/translation="MSYEVESKKEIPIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNLKEKKAL
FLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKYLKDLALFW
RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDNKLPKHGF
HQMPKEYSQILQLHMKGILKLQFSKCEVA"
Feature XM_024447977 : 1 segment
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