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Mus musculus forkhead box L1 (Foxl1), mRNA

NCBI Reference Sequence: NM_008024.2

FASTA Graphics 

LOCUS       NM_008024               2960 bp    mRNA    linear   ROD 16-NOV-2021
DEFINITION  Mus musculus forkhead box L1 (Foxl1), mRNA.
ACCESSION   NM_008024
VERSION     NM_008024.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2960)
  AUTHORS   Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S,
            Toyokuni S, Hatada I, Morimoto M and Yoshida K.
  TITLE     Mice lacking DYRK2 exhibit congenital malformations with lung
            hypoplasia and altered Foxf1 expression gradient
  JOURNAL   Commun Biol 4 (1), 1204 (2021)
   PUBMED   34671097
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2960)
  AUTHORS   Kondo A and Kaestner KH.
  TITLE     FoxL1(+) mesenchymal cells are a critical source of Wnt5a for
            midgut elongation during mouse embryonic intestinal development
  JOURNAL   Cells Dev 165, 203662 (2021)
   PUBMED   33993983
REFERENCE   3  (bases 1 to 2960)
  AUTHORS   Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa
            MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO and
            Kispert A.
  TITLE     Delayed onset of smooth muscle cell differentiation leads to
            hydroureter formation in mice with conditional loss of the zinc
            finger transcription factor gene Gata2 in the ureteric mesenchyme
  JOURNAL   J Pathol 248 (4), 452-463 (2019)
   PUBMED   30916783
REFERENCE   4  (bases 1 to 2960)
  AUTHORS   Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa
            M, Kelley MW, Wangemann P, Morell RJ and Griffith AJ.
  TITLE     Molecular architecture underlying fluid absorption by the
            developing inner ear
  JOURNAL   Elife 6, e26851 (2017)
   PUBMED   28994389
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2960)
  AUTHORS   Chan AL, La HM, Legrand JMD, Makela JA, Eichenlaub M, De Seram M,
            Ramialison M and Hobbs RM.
  TITLE     Germline Stem Cell Activity Is Sustained by SALL4-Dependent
            Silencing of Distinct Tumor Suppressor Genes
  JOURNAL   Stem Cell Reports 9 (3), 956-971 (2017)
   PUBMED   28867346
  REMARK    GeneRIF: SALL4 associated with the NuRD co-repressor and repressed
            expression of the tumor suppressor genes Foxl1 and Dusp4.
REFERENCE   6  (bases 1 to 2960)
  AUTHORS   Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M,
            Kageyama R, Guillemot F, Serup P and Madsen OD.
  TITLE     Control of endodermal endocrine development by Hes-1
  JOURNAL   Nat Genet 24 (1), 36-44 (2000)
   PUBMED   10615124
REFERENCE   7  (bases 1 to 2960)
  AUTHORS   Kaestner KH, Silberg DG, Traber PG and Schutz G.
  TITLE     The mesenchymal winged helix transcription factor Fkh6 is required
            for the control of gastrointestinal proliferation and
            differentiation
  JOURNAL   Genes Dev 11 (12), 1583-1595 (1997)
   PUBMED   9203584
REFERENCE   8  (bases 1 to 2960)
  AUTHORS   Kaestner KH, Bleckmann SC, Monaghan AP, Schlondorff J, Mincheva A,
            Lichter P and Schutz G.
  TITLE     Clustered arrangement of winged helix genes fkh-6 and MFH-1:
            possible implications for mesoderm development
  JOURNAL   Development 122 (6), 1751-1758 (1996)
   PUBMED   8674414
REFERENCE   9  (bases 1 to 2960)
  AUTHORS   Pierrou S, Hellqvist M, Samuelsson L, Enerback S and Carlsson P.
  TITLE     Cloning and characterization of seven human forkhead proteins:
            binding site specificity and DNA bending
  JOURNAL   EMBO J 13 (20), 5002-5012 (1994)
   PUBMED   7957066
REFERENCE   10 (bases 1 to 2960)
  AUTHORS   Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP and
            Schutz G.
  TITLE     Six members of the mouse forkhead gene family are developmentally
            regulated
  JOURNAL   Proc Natl Acad Sci U S A 90 (16), 7628-7631 (1993)
   PUBMED   7689224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127554.4.
            
            [WARNING] On Feb 1, 2022 this sequence was replaced by NM_008024.3.
            
            On Jan 5, 2007 this sequence version replaced NM_008024.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2960              AC127554.4         51268-54227
FEATURES             Location/Qualifiers
     source          1..2960
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 70.34 cM"
     gene            1..2960
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="forkhead box L1"
                     /db_xref="GeneID:14241"
                     /db_xref="MGI:MGI:1347469"
     exon            1..2960
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    140..142
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="upstream in-frame stop codon"
     misc_feature    156..1590
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="CpG_island (%GC=66.5, o/e=0.72, #CpGs=121)"
     CDS             278..1288
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="transcription factor FKH-6; forkhead-related
                     protein FKHL11; forkhead homolog 6"
                     /codon_start=1
                     /product="forkhead box protein L1"
                     /protein_id="NP_032050.2"
                     /db_xref="CCDS:CCDS59744.1"
                     /db_xref="GeneID:14241"
                     /db_xref="MGI:MGI:1347469"
                     /translation="MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGRV
                     EPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLS
                     LNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRTRVE
                     PPESEVGCDVGSPDLATALPTRAPDRSQSPAVGTARPALLPWPGPEPRDPDADLTVQG
                     AGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEAPGIP
                     KPVPGALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFLSYFPLQVPEATVLR
                     FH"
     misc_feature    695..919
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="propagated from UniProtKB/Swiss-Prot (Q64731.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    956..1033
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="propagated from UniProtKB/Swiss-Prot (Q64731.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
ORIGIN      
        1 agattttcag caatgaaatt ttaattaatg tgggtgggct gagaacacaa ggactgttta
       61 tcatagacaa tttattttcc agcgctaagt caacacataa tagcaaactt acaacaatta
      121 tttaacattt ttaaagccat gaagaaggga caaagcgcgc agcggctggg gagagcggct
      181 gatcgcaggg cagtcgcaca gagggctccc caggagggcc ctggtgcggg gcaaagtcct
      241 taggactccc cggtggagcg gagaggctgc tgtcgccatg agccacctct tcagtccccc
      301 gctggccgct ctggcagcct cgccgctgtt gtacgtgtac agccccgaga ggcctgggct
      361 gcccctggcc ttcgcccctg cggctgcact ggccggcccg ggccgcgtcg agcccccgca
      421 gaagccgccc tacagctaca tcgctcttat agccatggcg atccaggatg ctcccgagca
      481 gagggtcaca ctgaacggca tctaccagtt catcatggat cgcttcccgt tctaccacga
      541 caaccgccaa ggctggcaga acagcatccg ccacaacctg tcgctcaacg agtgcttcgt
      601 gaaggtgcca cgtgagaagg ggcggccggg caagggcagc tactggaccc tggacccccg
      661 ctgcttggac atgtttgaga acggcaatta tcggcgcagg aagaggaagc ccaagcccgc
      721 cgcgggttcc ccggaggcca agcgcacccg ggtcgagccg ccggagtccg aggtgggctg
      781 cgatgtaggg tccccggacc tggccactgc actcccgacg cgcgcgccgg atcgctccca
      841 atccccggca gtaggcaccg cgcggcccgc gctccttccc tggcccggcc ctgagccccg
      901 ggaccccgac gcggacctca cagtccaggg cgcaggggca gtggcaagcg gccagctcca
      961 gcgtccggca caccacctgg ggtcccctct gtgccccgcc cccagcggct ccccaaaagg
     1021 ttccaagtca aagagtttca gcatcgacag catcttggcc gtgagaccga cgccagcctc
     1081 aggggccgaa gcaccgggga tccctaagcc cgtgcctggc gcgctgggct cctctctgct
     1141 ggctgcctcc tccggcctag cgcctccctt caacgcttcg ctggtcttcg acgcgcacgt
     1201 ccagggcggc ttttcccagc tggggattcc cttcctttct tattttcctc tgcaggttcc
     1261 cgaggccaca gtgcttcgtt tccactaagg cggattagcg gctgcttccc tgcctcgcga
     1321 tccccccacc tccagtgagc caatgcctgt gggcgaagga gtcgccccgg tctctgccct
     1381 ggcagagact gagggtttgg agcagcgtac ccgtgccggc caaagtcgtg cactgagggg
     1441 cctcgtccat ctgctttctc cgaagatgac ttaaccagcc accggaagct ttgcagattt
     1501 aaaagactgg tccagtagag gacatggtcg ccgcacactc agccctcacg gttcgtctcc
     1561 agcagaagcc cctcgtaggc tttggcggcg ttgtacagtg accaccacaa gtccccactc
     1621 ggacctgagt ctcctgctga ccctgagggc aggacttaga gatatagcga acagctctat
     1681 gtggaggttc aactggatca tggaaggctc agcgggctcc gtgtggcata ggccttggct
     1741 ttgatctcat tggatgtggg gagcttgcag ccaggatgct ggggatgatc cgtggtccgc
     1801 aggctctggg aaagatgtag gcctggttaa cgtttacaac taaggttgaa caaaagcagg
     1861 ctcaccggaa atgctcaata tgaatagata aaccttcttc cagacaggga aaggctcatt
     1921 tattcttggc ttataaacca ggctcccctt tgctatagct agtagcttct tttaaggagc
     1981 cccgtgtgtt tggcacgtac tttggcttta cagtggcaca cctgccgcat tccacagcat
     2041 agtcctctgt tcacttctgc ttttcttttc tttttttttt tttgtgtggg ggggaggggt
     2101 tcgagacagg gtttctctgt atagccctgg ctgtcctgga actcactttg tagaccaggc
     2161 tggcctgcct ctgcctcccg agagctggga ttaaaggcgt actccaccat gcctggcctg
     2221 cttttctttt taaggcacca aaaaatttca ggggacacag aagggtgtgt gatcggaggg
     2281 attattatga ctcaagggcg ggtttttttt ttaacttctg tagcttttta agatctaagt
     2341 ccccccccca tctctctccc cccccccact cacactttcc agaaacacac acacagtgaa
     2401 ggactacatg taatcagaga ggctggggga gcatactact cctgagtgtg ggagatagat
     2461 agcttccagg agtgacaggg actctcttca gacaaagcct gtggtacctc aagtctgtgt
     2521 tccctttata tccctccagg gagatctaga tattgacatt acataaaccc ataagaggtg
     2581 accagagagc ggggttgagg gggagggggt ggggagatca acaaagtgct gactaaggca
     2641 actaagttgg ttaccgtgca gtgcagtcct gcttccaaat ttgggggaaa ctctcaggcc
     2701 tttggggtgc ccatgtttaa gcttgctggt gggctctgca actcagcttt cagaggaagg
     2761 aaagtgctgg tccttgatgt aaaaaaaagg accaaaaatt aagaattcta gggcataggt
     2821 ccacagtgat gtctcacaac aactaaggta tgccgtgcat cacacctgta atctcagtcc
     2881 ttgcaaggct gaggcagggg gattgctgtg agtttaagga tagcttgtgg cacagagtta
     2941 gacatgtctc aaactaaggg
//
278..1288
/gene="Foxl1"
/gene_synonym="fkh-6; Fkh6; FREAC7"
/note="transcription factor FKH-6; forkhead-related
protein FKHL11; forkhead homolog 6"
/codon_start=1
/product="forkhead box protein L1"
/protein_id="NP_032050.2"
/db_xref="CCDS:CCDS59744.1"
/db_xref="GeneID:14241"
/db_xref="MGI:MGI:1347469"
/translation="MSHLFSPPLAALAASPLLYVYSPERPGLPLAFAPAAALAGPGRV
EPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLS
LNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRTRVE
PPESEVGCDVGSPDLATALPTRAPDRSQSPAVGTARPALLPWPGPEPRDPDADLTVQG
AGAVASGQLQRPAHHLGSPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEAPGIP
KPVPGALGSSLLAASSGLAPPFNASLVFDAHVQGGFSQLGIPFLSYFPLQVPEATVLR
FH"
Feature NM_008024 : 1 segment
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