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Macaca mulatta inhibitor of nuclear factor kappa B kinase subunit beta (IKBKB), mRNA

NCBI Reference Sequence: NM_001265946.1

FASTA Graphics 

LOCUS       NM_001265946            3779 bp    mRNA    linear   PRI 22-FEB-2022
DEFINITION  Macaca mulatta inhibitor of nuclear factor kappa B kinase subunit
            beta (IKBKB), mRNA.
ACCESSION   NM_001265946 XM_001096913 XM_002805320 XM_002805321 XM_002805322
VERSION     NM_001265946.1
KEYWORDS    RefSeq.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 3779)
  AUTHORS   Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S,
            Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Marcais G,
            Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA
            and Norgren RB Jr.
  TITLE     A new rhesus macaque assembly and annotation for next-generation
            sequencing analyses
  JOURNAL   Biol Direct 9 (1), 20 (2014)
   PUBMED   25319552
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3779)
  AUTHORS   Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li
            Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson
            JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J,
            Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N,
            Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B,
            Nielsen R, Yang H, Wang J, Wang X and Wang J.
  TITLE     Genome sequencing and comparison of two nonhuman primate animal
            models, the cynomolgus and Chinese rhesus macaques
  JOURNAL   Nat Biotechnol 29 (11), 1019-1023 (2011)
   PUBMED   22002653
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JV046971.1.
            
            On or before May 26, 2012 this sequence version replaced
            XM_001096913.2, XM_002805320.1, XM_002805321.1, XM_002805322.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JV046971.1, JU475461.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4688317, SAMEA4688321
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3779
                     /organism="Macaca mulatta"
                     /mol_type="mRNA"
                     /db_xref="taxon:9544"
                     /chromosome="8"
                     /map="8"
     gene            1..3779
                     /gene="IKBKB"
                     /note="inhibitor of nuclear factor kappa B kinase subunit
                     beta"
                     /db_xref="GeneID:704683"
                     /db_xref="VGNC:VGNC:84006"
     exon            1..38
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            39..161
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    42..44
                     /gene="IKBKB"
                     /note="upstream in-frame stop codon"
     CDS             57..2327
                     /gene="IKBKB"
                     /EC_number="2.7.11.10"
                     /note="inhibitor of kappa light polypeptide gene enhancer
                     in B-cells, kinase beta"
                     /codon_start=1
                     /product="inhibitor of nuclear factor kappa-B kinase
                     subunit beta"
                     /protein_id="NP_001252875.1"
                     /db_xref="GeneID:704683"
                     /db_xref="VGNC:VGNC:84006"
                     /translation="MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIK
                     QCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
                     DLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRL
                     IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
                     FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKW
                     LQLMLMWHPRQRGTDPKYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQ
                     SLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGRTLDMDLVFLFDN
                     SKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQG
                     QRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSD
                     KLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQ
                     ARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALE
                     LLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLS
                     QPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWS
                     WLQTEEEEHSCLEQAS"
     exon            162..256
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            257..374
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            375..444
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            445..533
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            534..623
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            624..748
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            749..856
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            857..986
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1181
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1296
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1420
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1572
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1634
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1744
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1794
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1894
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2042
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            2043..2170
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2261
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
     exon            2262..3779
                     /gene="IKBKB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggggagccc tccccctgcc ccgcgtccct gccgacagag ttagcacgac atcagtatga
       61 gctggtcacc ttccctgaca acccagacat gtggggcctg ggaaatgaaa gagcgccttg
      121 ggacaggggg atttggaaat gtcatccgat ggcacaatca ggaaacaggt gagcagattg
      181 ccatcaagca gtgccggcag gagctcagcc cccggaatcg agagcggtgg tgcctggaga
      241 tccagatcat gagaaggctg acgcacccca atgtggtggc tgcccgagat gtccctgagg
      301 ggatgcagaa cttggcgccc aatgacttgc ccctgctggc catggagtat tgccaaggag
      361 gagatctccg gaagtacctg aaccagtttg agaattgctg tggtctgcgg gaaggtgcca
      421 tcctcacctt gctgagtgac attgcctctg cacttagata ccttcatgaa aacagaatca
      481 tccatcggga tctaaagcca gaaaacatcg tcctgcagca aggagaacag aggttaatac
      541 acaaaattat tgacctagga tatgccaagg agctggatca gggcagtctt tgcacgtcat
      601 tcgtggggac cctgcagtac ctggccccag agctgctgga gcagcagaag tacacagtga
      661 ccgtcgacta ctggagcttt ggcaccctgg ccttcgagtg catcacgggc ttccggccct
      721 tcctccccaa ctggcagccc gtgcagtggc attcgaaagt ccggcagaag agtgaggtgg
      781 atattgttgt cagcgaagac ttgaatggaa cagtgaagtt ttcaagctct ttaccctacc
      841 ccaataatct taacagcgtc ctggctgagc gactggagaa gtggctgcaa ctgatgctga
      901 tgtggcatcc ccgacagagg ggcacagatc ccaagtatgg gcccaatggc tgcttcaagg
      961 ccctggatga catcttaaac ttaaagctgg ttcatatctt gaacatggtc acaggcacca
     1021 tccacaccta ccctgtgaca gaggacgaga gtctgcagag cttgaaggcc agaatccagc
     1081 aggacacggg catcccagag gaggaccagg agctgctgca ggaagcgggc ctggcgttga
     1141 tccccgataa acctgccact cagtgtattt cagatggcaa gttaaatgag ggccgcacat
     1201 tggacatgga tcttgttttt ctctttgaca acagtaaaat cacctatgag actcagatct
     1261 ccccacggcc ccaacctgaa agtgtcagct gtatccttca agagcccaag aggaacctcg
     1321 ccttcttcca gctgaggaag gtgtggggcc aggtctggca cagcatccag accctaaagg
     1381 aggattgcaa ccggctgcag cagggacagc gagccgccat gatgaatctc ctccggaaca
     1441 acagctgcct ctccaagatg aagaattcca tggcttccat gtctcagcag ctcaaggcca
     1501 agttggattt cttcaaaacc agcatccaga ttgacctgga gaagtacagc gagcaaactg
     1561 agtttgggat cacatcagat aaactgctgc tggcctggag ggaaatggag caggccgtgg
     1621 agctctgtgg gcgggagaac gaagtgaaac tcctggtaga acggatgatg gctctgcaga
     1681 cggacatcgt ggacttacag aggagcccca tgggccggaa gcagggggga acattggacg
     1741 acctagagga gcaagcaagg gagctgtaca ggagactaag ggaaaagcct cgagaccagc
     1801 gaactgaggg tgacagtcag gaaatggtac ggctgctgct tcaggcaatt cagagcttcg
     1861 agaagaaagt gcgagtgatc tatacacagc tcagtaaaac tgtggtttgc aagcagaagg
     1921 cgctggaact gttgcccaag gtggaagagg tggtgagctt aatgaatgag gatgagaaga
     1981 ctgttgtccg gctgcaggag aagcggcaga aggagctctg gaatctcctg aagattgctt
     2041 gtagcaaggt ccgtggtcct gtcagtggaa gcccggatag catgaatgcc tctcgactta
     2101 gccagcctgg gcagctgatg tctcagccct ccacggcctc caacagctta cccgaaccag
     2161 ccaagaagag tgaagaactg gtggccgaag cacataacct gtgcaccctg ctagaaaatg
     2221 ccatacagga caccgtgagg gagcaagacc agagtttcac ggccctagac tggagctggt
     2281 tacagacgga agaagaagag cacagctgcc tggagcaggc ctcctgatgt gggggaactt
     2341 gaccccctga catggggctg tccatagcag accttgtgca gtggggggac tcgaccccct
     2401 gacatgtggc tgcctggagc aggcctcctg acgtggggct gcctggctgc agctctcaca
     2461 tggcggttcc tgctgcactg atggcccagc agtctctggt atccagatgg agctctcact
     2521 taagcagctg tgactttcac ccaggaccca gggcgcagcc ctccgcaggc actgccggca
     2581 ccttgtctgc acactggagg tcctccatta cagaggccca gcgcacgatg ccggccccac
     2641 gagcgttcag ggctagagcc acagcagctc cttcctctgc cttgagaaaa gtgcttggag
     2701 tacggtttgc tacacacgtg actggacagt gtccaattca aatctttcag ggcagagtcg
     2761 gagcagcgct tggtgccagc ctgtcctctc ctgctctcca atggccccgc tccctgtcct
     2821 ctctcacttt acagcttgtg tttcttctgg attcagcttc tcttaaacag acagtttaat
     2881 tatagttgtg gcctggcccc atcctcactt cctcttatta tttcactgct gctaaaattg
     2941 tatttttacc tactgctctg ggggttgtcc tcttttcggc aaagttggag tgagtgccaa
     3001 gctctccatc tgtggtcctt tcagccacag agagactcac cgtagtaagg gtaggagagc
     3061 agctgcctta ttctgagtcc caaagattac ttgggggtga ttgtcacaga ggagggacag
     3121 aaaggatatc tgctgaccgc tggcctgccc acaccatgcc cacgtctccg ttcctgctca
     3181 agaatgtgtg cgtgtggcag tgctgggctg gggagtccct gtctctccca gcatctagca
     3241 gtattaaatg gattcatttt aaaaatagct tctatatttt gtaacatgtc tcaaacactc
     3301 atactgggtt ccacaatcca ctgttagaat accgatggtt agggtttctg aactaaataa
     3361 tgtatcgtgc ctggatcatt actagtgcca taaccctgct tcttcaacat ttcacagaac
     3421 ttctctttta tataaaggca agagcataaa atgagttcag atgatcacaa acaggtgagt
     3481 gtttttggag aagaaagttg gagtaggaga ctttcacaag tatggagata gaatgaagtg
     3541 ttctttggtc aagtaagttt agggaatgat taatgtttca cttgctttat ggagattcac
     3601 actatgtact gggaaagtat ctgaaaagac ttaaagaaac ccgcttaact ttgtgtaaaa
     3661 acactgttta ccaatgtcat ttggctatag aaacattttc tcctgctgat tgtgtgtgtg
     3721 aaacaagtat taacattcca atgaagtagc atttaataaa gcacgatttt ggaaacctg
//
57..2327
/gene="IKBKB"
/EC_number="2.7.11.10"
/note="inhibitor of kappa light polypeptide gene enhancer
in B-cells, kinase beta"
/codon_start=1
/product="inhibitor of nuclear factor kappa-B kinase
subunit beta"
/protein_id="NP_001252875.1"
/db_xref="GeneID:704683"
/db_xref="VGNC:VGNC:84006"
/translation="MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIK
QCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
DLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRL
IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKW
LQLMLMWHPRQRGTDPKYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQ
SLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGRTLDMDLVFLFDN
SKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQG
QRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSD
KLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQ
ARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALE
LLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLS
QPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWS
WLQTEEEEHSCLEQAS"
Feature NM_001265946 : 1 segment
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