LOCUS NM_001265946 3779 bp mRNA linear PRI 22-FEB-2022
DEFINITION Macaca mulatta inhibitor of nuclear factor kappa B kinase subunit
beta (IKBKB), mRNA.
ACCESSION NM_001265946 XM_001096913 XM_002805320 XM_002805321 XM_002805322
VERSION NM_001265946.1
KEYWORDS RefSeq.
SOURCE Macaca mulatta (Rhesus monkey)
ORGANISM Macaca mulatta
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE 1 (bases 1 to 3779)
AUTHORS Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S,
Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Marcais G,
Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA
and Norgren RB Jr.
TITLE A new rhesus macaque assembly and annotation for next-generation
sequencing analyses
JOURNAL Biol Direct 9 (1), 20 (2014)
PUBMED 25319552
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 3779)
AUTHORS Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li
Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson
JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J,
Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N,
Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B,
Nielsen R, Yang H, Wang J, Wang X and Wang J.
TITLE Genome sequencing and comparison of two nonhuman primate animal
models, the cynomolgus and Chinese rhesus macaques
JOURNAL Nat Biotechnol 29 (11), 1019-1023 (2011)
PUBMED 22002653
REMARK Publication Status: Online-Only
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from JV046971.1.
On or before May 26, 2012 this sequence version replaced
XM_001096913.2, XM_002805320.1, XM_002805321.1, XM_002805322.1.
##Evidence-Data-START##
Transcript exon combination :: JV046971.1, JU475461.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA4688317, SAMEA4688321
[ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..3779
/organism="Macaca mulatta"
/mol_type="mRNA"
/db_xref="taxon:9544"
/chromosome="8"
/map="8"
gene 1..3779
/gene="IKBKB"
/note="inhibitor of nuclear factor kappa B kinase subunit
beta"
/db_xref="GeneID:704683"
/db_xref="VGNC:VGNC:84006"
exon 1..38
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 39..161
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
misc_feature 42..44
/gene="IKBKB"
/note="upstream in-frame stop codon"
CDS 57..2327
/gene="IKBKB"
/EC_number="2.7.11.10"
/note="inhibitor of kappa light polypeptide gene enhancer
in B-cells, kinase beta"
/codon_start=1
/product="inhibitor of nuclear factor kappa-B kinase
subunit beta"
/protein_id="NP_001252875.1"
/db_xref="GeneID:704683"
/db_xref="VGNC:VGNC:84006"
/translation="MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIK
QCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
DLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRL
IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKW
LQLMLMWHPRQRGTDPKYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQ
SLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGRTLDMDLVFLFDN
SKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQG
QRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSD
KLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQ
ARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALE
LLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLS
QPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWS
WLQTEEEEHSCLEQAS"
exon 162..256
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 257..374
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 375..444
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 445..533
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 534..623
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 624..748
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 749..856
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 857..986
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 987..1181
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1182..1296
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1297..1420
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1421..1572
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1573..1634
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1635..1744
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1745..1794
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1795..1894
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 1895..2042
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 2043..2170
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 2171..2261
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
exon 2262..3779
/gene="IKBKB"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 cggggagccc tccccctgcc ccgcgtccct gccgacagag ttagcacgac atcagtatga
61 gctggtcacc ttccctgaca acccagacat gtggggcctg ggaaatgaaa gagcgccttg
121 ggacaggggg atttggaaat gtcatccgat ggcacaatca ggaaacaggt gagcagattg
181 ccatcaagca gtgccggcag gagctcagcc cccggaatcg agagcggtgg tgcctggaga
241 tccagatcat gagaaggctg acgcacccca atgtggtggc tgcccgagat gtccctgagg
301 ggatgcagaa cttggcgccc aatgacttgc ccctgctggc catggagtat tgccaaggag
361 gagatctccg gaagtacctg aaccagtttg agaattgctg tggtctgcgg gaaggtgcca
421 tcctcacctt gctgagtgac attgcctctg cacttagata ccttcatgaa aacagaatca
481 tccatcggga tctaaagcca gaaaacatcg tcctgcagca aggagaacag aggttaatac
541 acaaaattat tgacctagga tatgccaagg agctggatca gggcagtctt tgcacgtcat
601 tcgtggggac cctgcagtac ctggccccag agctgctgga gcagcagaag tacacagtga
661 ccgtcgacta ctggagcttt ggcaccctgg ccttcgagtg catcacgggc ttccggccct
721 tcctccccaa ctggcagccc gtgcagtggc attcgaaagt ccggcagaag agtgaggtgg
781 atattgttgt cagcgaagac ttgaatggaa cagtgaagtt ttcaagctct ttaccctacc
841 ccaataatct taacagcgtc ctggctgagc gactggagaa gtggctgcaa ctgatgctga
901 tgtggcatcc ccgacagagg ggcacagatc ccaagtatgg gcccaatggc tgcttcaagg
961 ccctggatga catcttaaac ttaaagctgg ttcatatctt gaacatggtc acaggcacca
1021 tccacaccta ccctgtgaca gaggacgaga gtctgcagag cttgaaggcc agaatccagc
1081 aggacacggg catcccagag gaggaccagg agctgctgca ggaagcgggc ctggcgttga
1141 tccccgataa acctgccact cagtgtattt cagatggcaa gttaaatgag ggccgcacat
1201 tggacatgga tcttgttttt ctctttgaca acagtaaaat cacctatgag actcagatct
1261 ccccacggcc ccaacctgaa agtgtcagct gtatccttca agagcccaag aggaacctcg
1321 ccttcttcca gctgaggaag gtgtggggcc aggtctggca cagcatccag accctaaagg
1381 aggattgcaa ccggctgcag cagggacagc gagccgccat gatgaatctc ctccggaaca
1441 acagctgcct ctccaagatg aagaattcca tggcttccat gtctcagcag ctcaaggcca
1501 agttggattt cttcaaaacc agcatccaga ttgacctgga gaagtacagc gagcaaactg
1561 agtttgggat cacatcagat aaactgctgc tggcctggag ggaaatggag caggccgtgg
1621 agctctgtgg gcgggagaac gaagtgaaac tcctggtaga acggatgatg gctctgcaga
1681 cggacatcgt ggacttacag aggagcccca tgggccggaa gcagggggga acattggacg
1741 acctagagga gcaagcaagg gagctgtaca ggagactaag ggaaaagcct cgagaccagc
1801 gaactgaggg tgacagtcag gaaatggtac ggctgctgct tcaggcaatt cagagcttcg
1861 agaagaaagt gcgagtgatc tatacacagc tcagtaaaac tgtggtttgc aagcagaagg
1921 cgctggaact gttgcccaag gtggaagagg tggtgagctt aatgaatgag gatgagaaga
1981 ctgttgtccg gctgcaggag aagcggcaga aggagctctg gaatctcctg aagattgctt
2041 gtagcaaggt ccgtggtcct gtcagtggaa gcccggatag catgaatgcc tctcgactta
2101 gccagcctgg gcagctgatg tctcagccct ccacggcctc caacagctta cccgaaccag
2161 ccaagaagag tgaagaactg gtggccgaag cacataacct gtgcaccctg ctagaaaatg
2221 ccatacagga caccgtgagg gagcaagacc agagtttcac ggccctagac tggagctggt
2281 tacagacgga agaagaagag cacagctgcc tggagcaggc ctcctgatgt gggggaactt
2341 gaccccctga catggggctg tccatagcag accttgtgca gtggggggac tcgaccccct
2401 gacatgtggc tgcctggagc aggcctcctg acgtggggct gcctggctgc agctctcaca
2461 tggcggttcc tgctgcactg atggcccagc agtctctggt atccagatgg agctctcact
2521 taagcagctg tgactttcac ccaggaccca gggcgcagcc ctccgcaggc actgccggca
2581 ccttgtctgc acactggagg tcctccatta cagaggccca gcgcacgatg ccggccccac
2641 gagcgttcag ggctagagcc acagcagctc cttcctctgc cttgagaaaa gtgcttggag
2701 tacggtttgc tacacacgtg actggacagt gtccaattca aatctttcag ggcagagtcg
2761 gagcagcgct tggtgccagc ctgtcctctc ctgctctcca atggccccgc tccctgtcct
2821 ctctcacttt acagcttgtg tttcttctgg attcagcttc tcttaaacag acagtttaat
2881 tatagttgtg gcctggcccc atcctcactt cctcttatta tttcactgct gctaaaattg
2941 tatttttacc tactgctctg ggggttgtcc tcttttcggc aaagttggag tgagtgccaa
3001 gctctccatc tgtggtcctt tcagccacag agagactcac cgtagtaagg gtaggagagc
3061 agctgcctta ttctgagtcc caaagattac ttgggggtga ttgtcacaga ggagggacag
3121 aaaggatatc tgctgaccgc tggcctgccc acaccatgcc cacgtctccg ttcctgctca
3181 agaatgtgtg cgtgtggcag tgctgggctg gggagtccct gtctctccca gcatctagca
3241 gtattaaatg gattcatttt aaaaatagct tctatatttt gtaacatgtc tcaaacactc
3301 atactgggtt ccacaatcca ctgttagaat accgatggtt agggtttctg aactaaataa
3361 tgtatcgtgc ctggatcatt actagtgcca taaccctgct tcttcaacat ttcacagaac
3421 ttctctttta tataaaggca agagcataaa atgagttcag atgatcacaa acaggtgagt
3481 gtttttggag aagaaagttg gagtaggaga ctttcacaag tatggagata gaatgaagtg
3541 ttctttggtc aagtaagttt agggaatgat taatgtttca cttgctttat ggagattcac
3601 actatgtact gggaaagtat ctgaaaagac ttaaagaaac ccgcttaact ttgtgtaaaa
3661 acactgttta ccaatgtcat ttggctatag aaacattttc tcctgctgat tgtgtgtgtg
3721 aaacaagtat taacattcca atgaagtagc atttaataaa gcacgatttt ggaaacctg
//