LOCUS NM_001201718 6789 bp mRNA linear INV 26-DEC-2023
DEFINITION Drosophila melanogaster paralytic (para), transcript variant AZ,
mRNA.
ACCESSION NM_001201718
VERSION NM_001201718.1
DBLINK BioProject: PRJNA164
BioSample: SAMN02803731
KEYWORDS RefSeq.
SOURCE Drosophila melanogaster (fruit fly)
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (bases 1 to 6789)
AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
Strelets,V., Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: Impact of
High-Throughput Data
JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015)
PUBMED 26109357
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 6789)
AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: The
Rule-Benders
JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015)
PUBMED 26109356
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 6789)
AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
TITLE The Release 6 reference sequence of the Drosophila melanogaster
genome
JOURNAL Genome Res 25 (3), 445-458 (2015)
PUBMED 25589440
REFERENCE 4 (bases 1 to 6789)
AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
TITLE Sequence finishing and mapping of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1625-1628 (2007)
PUBMED 17569867
REFERENCE 5 (bases 1 to 6789)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
TITLE The Release 5.1 annotation of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1586-1591 (2007)
PUBMED 17569856
REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE 6 (bases 1 to 6789)
AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
Ashburner,M. and Anxolabehere,D.
TITLE Combined evidence annotation of transposable elements in genome
sequences
JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005)
PUBMED 16110336
REFERENCE 7 (bases 1 to 6789)
AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
Celniker,S.E., Rubin,G.M. and Karpen,G.H.
TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly
JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002)
PUBMED 12537574
REFERENCE 8 (bases 1 to 6789)
AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
Rubin,G.M., Ashburner,M. and Celniker,S.E.
TITLE The transposable elements of the Drosophila melanogaster
euchromatin: a genomics perspective
JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002)
PUBMED 12537573
REFERENCE 9 (bases 1 to 6789)
AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
Rubin,G.M. and Lewis,S.E.
TITLE Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review
JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002)
PUBMED 12537572
REFERENCE 10 (bases 1 to 6789)
AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
Gibbs,R.A. and Rubin,G.M.
TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence
JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002)
PUBMED 12537568
REFERENCE 11 (bases 1 to 6789)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
PUBMED 10731132
REFERENCE 12 (bases 1 to 6789)
AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
Smith,E., Yu,C. and Rubin,G.
CONSRTM Berkeley Drosophila Genome Project
TITLE Drosophila melanogaster release 4 sequence
JOURNAL Unpublished
REFERENCE 13 (bases 1 to 6789)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 14 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 15 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 16 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 17 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 18 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 19 (bases 1 to 6789)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 20 (bases 1 to 6789)
AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
Park,S., Svirskas,R. and Karpen,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 21 (bases 1 to 6789)
AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
Svirskas,R. and Rubin,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 22 (bases 1 to 6789)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
CONSRTM Drosophila Heterochromatin Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE 23 (bases 1 to 6789)
AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
Rockville, MD 20850, USA
COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This
record is derived from an annotated genomic sequence (NC_004354).
##Genome-Annotation-Data-START##
Annotation Provider :: FlyBase
Annotation Status :: Full annotation
Annotation Version :: Release 6.54
URL :: http://flybase.org
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..6789
/organism="Drosophila melanogaster"
/mol_type="mRNA"
/db_xref="taxon:7227"
/chromosome="X"
/genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
gene 1..6789
/gene="para"
/locus_tag="Dmel_CG9907"
/gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav;
DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da;
l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para;
para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC"
/note="paralytic"
/map="14C8-14E1"
/db_xref="FLYBASE:FBgn0285944"
/db_xref="GeneID:32619"
CDS 269..6604
/gene="para"
/locus_tag="Dmel_CG9907"
/gene_synonym="bas; bss; CG9907; Dmel\CG9907; DmNav;
DmNav1; DmNa[[v]]; DmNa[[V]]; DmNa[[v]]1; l(1)14Da;
l(1)ESHS48; lincRNA.S9469; Nav1; Ocd; olfD; par; Para;
para13-5; sbl; sbl-1; Scn1alpha; Shu; Shudderer; VSSC"
/note="CG9907 gene product from transcript CG9907-RAZ;
CG9907-PAZ; para-PAZ; bang sensitive; voltage-sensitive
sodium channel; shudderer; bang senseless; bangsenseless;
voltage gated sodium ion channel; paralyzed; Out-cold; Out
cold; smell-blind; smellblind; paralytic; bang-senseless"
/codon_start=1
/product="paralytic, isoform AZ"
/protein_id="NP_001188647.1"
/db_xref="FLYBASE:FBpp0292719"
/db_xref="GeneID:32619"
/db_xref="FLYBASE:FBgn0285944"
/translation="MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERK
RAEGEVIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPLEDIDPYYSNVL
TFVVVSKGKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI
MPTTPTVESTEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTM
GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL
MGLQIYMGVLTQKCIKKFPLDGSWGNLTDENWDYHNRNSSNWYSEDEGISFPLCGNIS
GAGQCDDDYVCLQGFGPNPNYGYTSFDSFGWAFLSAFRLMTQDFWEDLYQLVLRAAGP
WHMLFFIVIIFLGSFYLVNLILAIVAMSYDELQKKAEEEEAAEEEAIREAEEAAAAKA
AKLEERANAQAQAAADAAAAEEAALHPEMAKSPTYSCISYELFVGGEKGNDDNNKEKM
SIRSVEVESESVSVIQRQPAPTTAHQATKVRKVSTYTIRNGRGRFGIPGSDRKPLVLS
TYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSHQSRISYTSHGD
LLGGMAVMGVSTMTKESKLRNRNTRNQSVGATNGGTTCLDTNHKLDHRDYEIGLECTD
EAGKIKHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDRGVSVYYFPTED
DDEDGPTFKDKALEVILKGIDVFCVWDCCWVWLKFQEWVSLIVFDPFVELFITLCIVV
NTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMAMSPKYYFQEGWNIFDFI
IVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFV
LCIIIFIFAVMGMQLFGKNYHDHKDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIES
MWDCMYVGDVSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSSLSAPTADNDTNKIAE
AFNRIGRFKSWVKRNIADCFKLIRNKLTNQISDQPSGKGVCRCISAEHGDNELELGHD
EILADGLIKKGIKEQTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNNATMIGNSINHQ
DNRLEHELNHRGLSLQDDDTASINSYGSHKNRPFKDESHKGSAETMEGEEKRDASKED
LGLDEELDEEGECEEGPLDGDIIIHAHDEDILDEYPADCCPDSYYKKFPILAGDDDSP
FWQGWGNLRLKTFQLIENKYFETAVITMILMSSLALALEDVHLPQRPILQDILYYMDR
IFTVIFFLEMLIKWLALGFKVYFTNAWCWLDFVIVMLSLINLAAVWSGADDVPAFRSM
RTLRALRPLRAVSRWEGMKVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY
FKCEDMNGTKLSHEIIPNRNACESENYTWVNSAMNFDHVGNAYLCLFQVATFKGWIQI
MNDAIDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGVIIDNFNEQKKKAGG
SLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDIIIMLFIG
LNMFTMTLDRYDASDTYNAVLDYLNAIFVVIFSSECLLKIFALRYHYFIEPWNLFDVV
VVILSILGLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLP
ALFNICLLLFLVMFIFAIFGMSFFMHVKEKSGINDVYNFKTFGQSMILLFQMSTSAGW
DGVLDAIINEEACDPPDNDKGYPGNCGSATVGITFLLSYLVISFLIVINMYIAVILEN
YSQATEDVQEGLTDDDYDMYYEIWQQFDPEGTQYIRYDQLSEFLDVLEPPLQIHKPNK
YKIISMDIPICRGDLMYCVDILDALTKDFFARKGNPIEETGEIGEIAARPDTEGYEPV
SSTLWRQREEYCARLIQHAWRKHKARGEGGGSFEPDTDHGDGGDPDAGDPAPDEATDG
DAPAGGDGSVNGTAEGAADADESNVNSPGEDAAAAAAAAAAAAAAGTTTAGSPGAGSA
GRQTAVLVESDGFVTKNGHKVVIHSRSPSITSRTADV"
ORIGIN
1 caacaacaac aatacaagca agcacgctca caacaaaagc agcaacagca acaacaacca
61 caatagcaac tacagcaaca acaacatcag cggatagagc gagcagccag gcacaacatc
121 gatagacatc gattaacgca tcgtgctaag cggcgggcgc taatcgaaca tggcgcctcg
181 gatatagttg tagctttaat gtagcaggcg acatccatgt gcctcatgcc ttggaaatct
241 aaggctctca tcgttggccg catagacaat gacagaagat tccgactcga tatctgagga
301 agaacgcagt ttgttccgtc cctttacccg cgaatcattg gtgcaaatcg aacaacgcat
361 tgccgctgaa catgaaaagc agaaggagct ggaaagaaag agagccgagg gagaggtgat
421 ccgatatgat gacgaggacg aggatgaagg tccacaaccg gatcctacac ttgaacaggg
481 tgtgccaata cctgttcgat tgcagggcag cttcccgccg gaattggcct ccactcctct
541 cgaggatatc gatccctact acagcaatgt actgacattc gtagttgtaa gcaaaggaaa
601 agatattttt cgcttttctg catcaaaagc aatgtggatg ctcgatccat tcaatccgat
661 acgtcgtgtg gccatttaca ttctagtgca tccattattt tccctattca tcatcaccac
721 aattctcgtc aactgcatcc tgatgataat gccgacaacg cccacggttg agtccactga
781 ggtgatattc accggaatct acacatttga atcagctgtt aaagtgatgg cacgaggttt
841 cattttatgc ccgtttacgt atcttagaga tgcatggaat tggctggact tcgtagtaat
901 agctttagct tatgtgacca tgggtataga tttaggtaat ctagcagccc tgcgaacgtt
961 tagggtgctg cgagcgctta aaaccgtagc cattgtgcca ggcttgaaga ccatcgtcgg
1021 cgccgtcatc gaatcggtga agaatctgcg cgatgtgatt atcctgacca tgttctccct
1081 gtcggtgttc gcgttgatgg gcctacagat ctatatgggc gtgctcacgc agaagtgcat
1141 caagaagttc ccgctggacg gttcctgggg caatctgacc gacgagaact gggactatca
1201 caatcgcaat agctccaatt ggtattccga ggacgagggc atctcatttc cgttatgcgg
1261 caatatatcc ggtgcggggc aatgcgacga cgattacgtg tgcctgcagg ggtttggtcc
1321 gaatccgaat tatggctaca ccagcttcga ttcgttcgga tgggctttcc tgtccgcctt
1381 ccggctgatg acacaggact tctgggagga tctgtaccag ctggtgttgc gcgccgccgg
1441 accatggcac atgctgttct ttatagtcat catcttccta ggttcattct atcttgtgaa
1501 tttgattttg gccattgttg ccatgtcgta tgacgaattg caaaagaagg ccgaagaaga
1561 agaggctgcc gaagaggagg cgatacgtga agcggaagaa gctgccgccg ccaaagcggc
1621 caagctggag gagcgggcca atgcgcaggc tcaggcagca gcggatgcgg ctgccgccga
1681 agaggctgca ctgcatccgg aaatggccaa gagtccgacg tattcttgca tcagctatga
1741 gctatttgtt ggcggcgaga agggcaacga tgacaacaac aaagagaaga tgtccattcg
1801 gagcgtcgag gtggagtcgg agtcggtgag cgttatacaa agacaaccag cacctaccac
1861 agcacaccaa gctaccaaag ttcgtaaagt gagcacgtac acgatacgga acggacgtgg
1921 ccgctttggt atacccggta gcgatcgtaa gccattggta ttgtcaacat atcaggatgc
1981 ccagcagcac ttgccctatg ccgacgactc gaatgccgtc accccgatgt ccgaagagaa
2041 tggggccatc atagtgcccg tgtactatgg caatctaggc tcccgacact catcgtatac
2101 ctcgcatcag tcccgaatat cgtatacctc acatggcgat ctactcggcg gcatggccgt
2161 catgggcgtc agcacaatga ccaaggagag caaattgcgc aaccggaaca cacgcaatca
2221 atcagtgggc gccaccaatg gcggcaccac ctgtctggac accaatcaca agctcgatca
2281 tcgcgactac gaaattggcc tggagtgcac ggacgaagct ggcaagatta aacatcatga
2341 caatcctttt atcgagcccg tccagacaca aacggtggtt gatatgaaag atgtgatggt
2401 cctgaatgac atcatcgaac aggccgctgg tcggcacagt cgggcaagcg atcgcggtgt
2461 ctccgtttac tatttcccaa cagaggacga tgacgaggat gggccgacgt tcaaagacaa
2521 ggcactcgaa gtgatcctca aaggcatcga tgtgttttgt gtgtgggact gttgctgggt
2581 ttggttgaaa tttcaggagt gggtatcgct catcgtcttc gatcccttcg tcgagctctt
2641 catcacgctg tgcattgtgg tcaacacgat gttcatggca atggatcacc acgatatgaa
2701 caaggagatg gaacgcgtgc tcaagagtgg caactatttc ttcaccgcca cctttgccat
2761 cgaggccacc atgaagctaa tggccatgag ccccaagtac tatttccagg agggctggaa
2821 catcttcgac ttcattatcg tggccctatc gctattggaa ctgggactcg agggtgtcca
2881 gggtctgtcc gtattgcgtt cctttcgatt gctgcgtgta ttcaaactgg ccaagtcttg
2941 gcccacactt aatttactca tttcgattat gggacgcacc atgggcgctt tgggtaatct
3001 gacatttgta ctttgcatta tcatcttcat ctttgcggtg atgggaatgc aactgttcgg
3061 aaagaattat catgatcaca aggaccgctt tccggatggc gacctgccgc gctggaactt
3121 caccgacttt atgcacagct tcatgatcgt gttccgggtg ctctgcggag aatggatcga
3181 gtccatgtgg gactgcatgt acgtgggcga tgtctcgtgc attcccttct tcttggccac
3241 cgttgtcatc ggcaatcttg tggtacttaa ccttttctta gccttgcttt tgtccaattt
3301 tggctcatct agcttatcag cgccgactgc cgataacgat acgaataaaa tagccgaggc
3361 cttcaatcga attggccgat ttaaaagttg ggttaagcgt aatattgctg attgtttcaa
3421 gttaatacgt aacaaattga caaatcaaat aagtgatcaa ccatcaggca aaggcgtttg
3481 tcgttgtata tctgcagagc atggtgacaa cgaactggag ctgggccacg acgagatcct
3541 cgccgacggc ctcatcaaga aggggatcaa ggagcagacg caactggagg tggccatcgg
3601 ggatggcatg gaattcacga tacacggcga catgaagaac aacaagccga agaaatccaa
3661 atatctaaat aacgcaacga tgattggcaa ctcaattaac caccaagaca atagactgga
3721 acacgagcta aaccatagag gtttgtcctt acaggacgac gacactgcca gcattaactc
3781 atatggtagc cataagaatc gaccattcaa ggacgagagc cacaagggca gcgccgagac
3841 gatggagggc gaggagaagc gcgacgccag caaggaggat ttaggtctcg acgaggaact
3901 ggacgaggag ggcgaatgcg aggagggccc gctcgacggt gatatcatta ttcatgcaca
3961 cgacgaggat atactcgatg aatatccagc tgattgctgc cccgattcgt actataagaa
4021 atttccgatc ttagccggtg acgatgactc gccgttctgg caaggatggg gcaatttacg
4081 actgaaaact tttcaattaa ttgaaaataa atattttgaa acagctgtta tcactatgat
4141 tttaatgagt agcttagctt tggcattaga agatgtacat ctgccacaaa gacccatact
4201 gcaggatatt ttatactata tggacagaat atttacggtt atattcttct tggaaatgtt
4261 aatcaagtgg ttggcgctcg gcttcaaagt gtacttcacc aacgcgtggt gttggctcga
4321 tttcgtgatt gtcatgctgt cgctaattaa tttggccgcg gtctggtccg gggccgatga
4381 tgtgcccgcc tttcgctcga tgcgaactct gcgcgccctg cgaccactgc gggcagtttc
4441 gcgctgggag ggcatgaaag tcgtcgttaa tgcgctggta caagctatac cgtccatctt
4501 caatgtgcta ttggtgtgtc taatattttg gctaattttt gccataatgg gtgtacagct
4561 ttttgctgga aaatatttta agtgcgagga catgaatggc acgaagctca gccacgagat
4621 cataccaaat cgcaatgcct gcgagagcga gaactacacg tgggtgaatt cagcaatgaa
4681 tttcgatcat gtaggtaacg cgtatctgtg ccttttccaa gtggccacct tcaaaggctg
4741 gatacaaatc atgaacgatg ctatcgattc acgagaggtg gacaagcaac caattcgtga
4801 aacgaacatc tacatgtatt tatatttcgt attcttcatc atatttggat catttttcac
4861 actcaatctg ttcattggtg ttatcattga taattttaat gagcaaaaga aaaaagcagg
4921 tggatcatta gaaatgttca tgacagaaga tcagaaaaag tactataatg ctatgaaaaa
4981 gatgggctct aaaaaaccat taaaagccat tccaagacca aggtggcgac cacaagcaat
5041 agtctttgaa atagtaaccg ataagaaatt cgatataatc attatgttat tcattggtct
5101 gaacatgttc accatgaccc tcgatcgtta cgatgcgtcg gacacgtata acgcggtcct
5161 agactatctc aatgcgatat tcgtagttat tttcagttcc gaatgtctat taaaaatatt
5221 cgctttacga tatcactatt ttattgagcc atggaattta tttgatgtag tagttgtcat
5281 tttatccatc ttaggtcttg tacttagcga tattatcgag aagtacttcg tgtcgccgac
5341 cctgctccga gtggtgcgtg tggcgaaagt gggccgtgtc cttcgactgg tgaagggagc
5401 caagggcatt cggacactgc tcttcgcgtt ggccatgtcg ctgccggccc tgttcaacat
5461 ctgcctgctg ctgttcctgg tcatgttcat ctttgccatt ttcggcatgt cgttcttcat
5521 gcacgtgaag gagaagagcg gcatcaacga cgtctacaac ttcaagacct ttggccagag
5581 catgatcctg ctctttcaga tgtcgacgtc agccggttgg gatggtgtac tggacgccat
5641 tatcaatgag gaagcatgcg atccacccga caacgacaaa ggctatccgg gcaattgtgg
5701 ttcagcgacc gttggaataa cgtttctcct ctcataccta gttataagct ttttgatagt
5761 tattaatatg tacattgctg tcattctcga gaactatagt caggccaccg aggacgtgca
5821 agagggtcta accgacgacg actacgacat gtactatgag atctggcagc aattcgatcc
5881 ggagggcacc cagtacatac gctatgatca gctgtccgaa ttcctggacg tactggagcc
5941 cccgctgcag atccacaaac cgaacaagta caagatcata tcgatggaca tacccatctg
6001 tcgcggtgac ctcatgtact gcgtcgacat cctcgacgcc cttacgaaag acttctttgc
6061 gcggaagggc aatccgatag aggagacggg tgagattggt gagatagcgg cccgcccgga
6121 tacggagggc tacgagcccg tctcatcaac gctgtggcgt cagcgtgagg agtactgcgc
6181 ccggctaatc cagcacgcct ggcgaaagca caaggcgcgc ggcgagggag gtgggtcctt
6241 tgagccggat acggatcatg gcgatggcgg tgatccggat gccggggacc cggcgcccga
6301 tgaagcaacg gacggcgatg cgcccgctgg tggagatggt agtgttaacg gtactgcaga
6361 aggagctgcc gatgccgatg agagtaatgt aaatagtccg ggtgaggatg cagcggcggc
6421 ggcagcagca gcagcagcag cggcggcggc gggcacgacg acggcgggaa gtcccggagc
6481 gggtagcgcc gggcgacaga ccgccgttct cgtggagagc gacgggttcg tgacgaagaa
6541 cggccacaag gtggtcatcc actcgcgatc gccgagcatc acgtcgcgca cggcggatgt
6601 ctgagccagg cctcgccccc ccctccaaga tgcacgcgag tattagcatg agtacgtgtt
6661 ggatgttgca tgttgcatca gcgatgcagc agcgacagtg agctaacaac aacagcaaca
6721 aggcgaacaa caagcataat tttctgctat ataatgaaag aacaccatac aaacaaatac
6781 aacaacaat
//