LOCUS CAC20525 316 aa linear PRI 06-JAN-2001
DEFINITION olfactory receptor [Homo sapiens].
ACCESSION CAC20525
VERSION CAC20525.1
DBSOURCE embl accession AJ302605.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Ziegler,A., Ehlers,A., Forbes,S.A., Trowsdale,J.,
Uchanska-Ziegler,B., Volz,A., Younger,R. and Beck,S.
TITLE Polymorphic olfactory receptor genes and HLA loci constitute
extended haplotypes
JOURNAL (in) Kasahara,M. (Ed.);
MAJOR HISTOCOMPATIBILITY COMPLEX-EVOLUTION, STRUCTURE, AND
FUNCTION: 110-130;
Springer-Verlag, Tokyo, Japan (2000)
REFERENCE 2
AUTHORS Ehlers,A., Beck,S., Forbes,S.A., Trowsdale,J., Volz,A., Younger,R.
and Ziegler,A.
TITLE MHC-linked olfactory receptor loci exhibit polymorphism and
contribute to extended HLA/OR-haplotypes
JOURNAL Unpublished
REFERENCE 3
AUTHORS Younger,R.M., Amadou,C., Bethel,G., Ehlers,A., Fischer Lindahl,K.,
Forbes,S.A., Horton,R., Milne,S., Mungall,A.J., Trowsdale,J.,
Volz,A., Ziegler,A. and Beck,S.
TITLE Characterisation of clustered MHC-linked Olfactory Receptor Genes
in Human and Mouse
JOURNAL Unpublished
REFERENCE 4
AUTHORS Ziegler,A., Ehlers,A., Forbes,S.A., Trowsdale,J., Volz,A.,
Younger,R.M. and Beck,S.
TITLE Polymorphisms in olfactory receptor genes: a cautionary note
JOURNAL Unpublished
REFERENCE 5 (residues 1 to 316)
AUTHORS Ehlers,A.
TITLE Direct Submission
JOURNAL Submitted (06-NOV-2000) Ehlers A., Institut fuer Immungenetik,
Universitaetsklinikum Charite, Spandauer Damm 130, 14050 Berlin,
GERMANY
FEATURES Location/Qualifiers
source 1..316
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="6"
/cell_line="KR3598"
Protein 1..316
/product="olfactory receptor"
Region 23..292
/region_name="7tmA_OR2B-like"
/note="olfactory receptor subfamily 2B and related
proteins, member of the class A family of
seven-transmembrane G protein-coupled receptors; cd15947"
/db_xref="CDD:320613"
Region 24..50
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320613"
Region 57..83
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320613"
Site order(79,82..83,95..100,102..103,106,151,153..157,193,
196..198,200..202,204..205,250,253..254,256..257,260,
266..267,269..271,274,277..278)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320613"
Region 95..125
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320613"
Region 138..159
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320613"
Region 193..223
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320613"
Region 230..260
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320613"
Region 267..292
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320613"
CDS 1..316
/gene="6M1-16*01"
/coded_by="AJ302605.1:1..951"
/db_xref="GOA:Q9GZK4"
/db_xref="HGNC:HGNC:8252"
/db_xref="InterPro:IPR000276"
/db_xref="InterPro:IPR000725"
/db_xref="InterPro:IPR015544"
/db_xref="InterPro:IPR017452"
/db_xref="UniProtKB/Swiss-Prot:Q9GZK4"
ORIGIN
1 mvnqsspmgf lllgfsehpa lertlfvvvf tsylltlvgn tliillsvly prlhspmyff
61 lsdlsfldlc fttscvpqml vnlwgpkkti sflgcsvqlf iflslgttec illtvmafdr
121 yvavcqplhy atiihprlcw qlasvawvms lvqsivqtps tlhlpfcphq qiddflcevp
181 slirlscgdt syneiqlavs svifvvvpls lilasygata qavlrinsat awrkafgtcs
241 shltvvtlfy ssviavylqp knpyaqgrgk ffglfyavgt pslnplvytl rnkeikralr
301 rllgkerdsr eswraa
//