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Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin), mRNA (cDNA clone MGC:88065 IMAGE:6186685), complete cds

GenBank: BC072457.1

FASTA Graphics 

LOCUS       BC072457                3178 bp    mRNA    linear   PRI 15-JUL-2006
DEFINITION  Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin),
            mRNA (cDNA clone MGC:88065 IMAGE:6186685), complete cds.
ACCESSION   BC072457
VERSION     BC072457.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3178)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 3178)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Dr. James R. Lupski
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 174 Row: m Column: 24
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 48675809.
FEATURES             Location/Qualifiers
     source          1..3178
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:88065 IMAGE:6186685"
                     /tissue_type="Peripheral Nervous System, dorsal root
                     ganglion"
                     /clone_lib="Lupski_dorsal_root_ganglion"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     gene            1..3178
                     /gene="SPARC"
                     /db_xref="GeneID:6678"
                     /db_xref="HGNC:HGNC:11219"
                     /db_xref="MIM:182120"
     CDS             106..1017
                     /gene="SPARC"
                     /codon_start=1
                     /product="secreted protein, acidic, cysteine-rich
                     (osteonectin)"
                     /protein_id="AAH72457.1"
                     /db_xref="GeneID:6678"
                     /db_xref="HGNC:HGNC:11219"
                     /db_xref="MIM:182120"
                     /translation="MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVG
                     ANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCP
                     APIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL
                     TEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLAR
                     DFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD
                     NDKYIALDEWAGCFGIKQKDIDKDLVI"
ORIGIN      
        1 gttgcctgtc tctaaacccc tccacattcc cgcggtcctt cagactgccc ggagagcgcg
       61 ctctgcctgc cgcctgcctg cctgccactg agggttccca gcaccatgag ggcctggatc
      121 ttctttctcc tttgcctggc cgggagggcc ttggcagccc ctcagcaaga agccctgcct
      181 gatgagacag aggtggtgga agaaactgtg gcagaggtga ctgaggtatc tgtgggagct
      241 aatcctgtcc aggtggaagt aggagaattt gatgatggtg cagaggaaac cgaagaggag
      301 gtggtggcgg aaaatccctg ccagaaccac cactgcaaac acggcaaggt gtgcgagctg
      361 gatgagaaca acacccccat gtgcgtgtgc caggacccca ccagctgccc agcccccatt
      421 ggcgagtttg agaaggtgtg cagcaatgac aacaagacct tcgactcttc ctgccacttc
      481 tttgccacaa agtgcaccct ggagggcacc aagaagggcc acaagctcca cctggactac
      541 atcgggcctt gcaaatacat ccccccttgc ctggactctg agctgaccga attccccctg
      601 cgcatgcggg actggctcaa gaacgtcctg gtcaccctgt atgagaggga tgaggacaac
      661 aaccttctga ctgagaagca gaagctgcgg gtgaagaaga tccatgagaa tgagaagcgc
      721 ctggaggcag gagaccaccc cgtggagctg ctggcccggg acttcgagaa gaactataac
      781 atgtacatct tccctgtaca ctggcagttc ggccagctgg accagcaccc cattgacggg
      841 tacctctccc acaccgagct ggctccactg cgtgctcccc tcatccccat ggagcattgc
      901 accacccgct ttttcgagac ctgtgacctg gacaatgaca agtacatcgc cctggatgag
      961 tgggccggct gcttcggcat caagcagaag gatatcgaca aggatcttgt gatctaaatc
     1021 cactccttcc acagtaccgg attctctctt taaccctccc cttcgtgttt cccccaatgt
     1081 ttaaaatgtt tggatggttt gttgttctgc ctggagacaa ggtgctaaca tagatttaag
     1141 tgaatacatt aacggtgcta aaaatgaaaa ttctaaccca agacatgaca ttcttagctg
     1201 taacttaact attaaggcct tttccacacg cattaatagt cccatttttc tcttgccatt
     1261 tgtagctttg cccattgtct tattggcaca tgggtggaca cggatctgct gggctctgcc
     1321 ttaaacacac attgcagctt caacttttct ctttagtgtt ctgtttgaaa ctaatactta
     1381 ccgagtcaga ctttgtgttc atttcatttc agggtcttgg ctgcctgtgg gcttccccag
     1441 gtggcctgga ggtgggcaaa gggaagtaac agacacacga tgttgtcaag gatggttttg
     1501 ggactagagg ctcagtggtg ggagagatcc ctgcagaacc caccaaccag aacgtggttt
     1561 gcctgaggct gtaactgaga gaaagattct ggggctgtgt tatgaaaata tagacattct
     1621 cacataagcc cagttcatca ccatttcctc ctttaccttt cagtgcagtt tcttttcaca
     1681 ttaggctgtt ggttcaaact tttgggagca cggactgtca gttctctggg aagtggtcag
     1741 cgcatcctgc agggcttctc ctcctctgtc ttttggagaa ccagggctct tctcaggggc
     1801 tctagggact gccaggctgt ttcagccagg aaggccaaaa tcaagagtga gatgtagaaa
     1861 gttgtaaaat agaaaaagtg gagttggtga atcggttgtt ctttcctcac atttggatga
     1921 ttgtcataag gtttttagca tgttcctcct tttcttcacc ctcccctttt ttcttctatt
     1981 aatcaagaga aacttcaaag ttaatgggat ggtcggatct cacaggctga gaactcgttc
     2041 acctccaagc atttcatgaa aaagctgctt cttattaatc atacaaactc tcaccatgat
     2101 gtgaagagtt tcacaaatcc ttcaaaataa aaagtaatga cttagaaact gccttcctgg
     2161 gtgatttgca tgtgtcttag tcttagtcac cttattatcc tgacacaaaa acacatgagc
     2221 atacatgtct acacatgact acacaaatgc aaacctttgc aaacacatta tgcttttgca
     2281 cacacacacc tgtacacaca caccggcatg tttatacaca gggagtgtat ggttcctgta
     2341 agcactaagt tagctgtttt catttaatga cctgtggttt aacccttttg atcactacca
     2401 ccattatcag caccagactg agcagctata tccttttatt aatcatggtc attcattcat
     2461 tcattcattc acaaaatatt tatgatgtat ttactctgca ccaggtccca tgccaagcac
     2521 tggggacaca gttatggcaa agtagacaaa gcatttgttc atttggagct tagagtccag
     2581 gaggaataca ttagataatg acacaatcaa atataaattg caagatgtca caggtgtgat
     2641 gaagggagag taggagagac catgagtatg tgtaacagga ggacacagca ttattctagt
     2701 gctgtactgt tccgtacggc agccactacc cacatgtaac tttttaagat ttaaatttaa
     2761 attagttaac attcaaaacg cagctcccca atcacactag caacatttca agtgcttgag
     2821 agccatgcat gattagtggt taccctattg aataggtcag aagtagaatc ttttcatcat
     2881 cacagaaagt tctattggac agtgctcttc tagatcatca taagactaca gagcactttt
     2941 caaagctcat gcatgttcat catgttagtg tcgtattttg agctggggtt ttgagactcc
     3001 ccttagagat agagaaacag acccaagaaa tgtgctcaat tgcaatgggc cacataccta
     3061 gatctccaga tgtcatttcc cctctcttat tttaagttat gttaagatta ctaaaacaat
     3121 aaaagctcct aaaaaatcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
106..1017
/gene="SPARC"
/codon_start=1
/product="secreted protein, acidic, cysteine-rich
(osteonectin)"
/protein_id="AAH72457.1"
/db_xref="GeneID:6678"
/db_xref="HGNC:HGNC:11219"
/db_xref="MIM:182120"
/translation="MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVG
ANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCP
APIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL
TEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLAR
DFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD
NDKYIALDEWAGCFGIKQKDIDKDLVI"
Feature BC072457 : 1 segment
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