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Chain A, Galactose oxidase

PDB: 2EIC_A

Identical Proteins FASTA Graphics 

LOCUS       2EIC_A                   639 aa            linear   PLN 31-OCT-2024
DEFINITION  Chain A, Galactose oxidase.
ACCESSION   2EIC_A
VERSION     2EIC_A
DBSOURCE    pdb: molecule 2EIC, chain A, release Oct 30, 2024;
            deposition: Mar 12, 2007;
            class: OXIDOREDUCTASE;
            source: Mmdb_id: 45605, Pdb_id 1: 2EIC;
            Exp. method: X-ray Diffraction.
KEYWORDS    .
SOURCE      Fusarium graminearum (Gibberella zeae)
  ORGANISM  Fusarium graminearum
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium.
REFERENCE   1  (residues 1 to 639)
  AUTHORS   Rogers,M.S., Tyler,E.M., Akyumani,N., Kurtis,C.R., Spooner,R.K.,
            Deacon,S.E., Tamber,S., Firbank,S.J., Mahmoud,K., Knowles,P.F.,
            Phillips,S.E., McPherson,M.J. and Dooley,D.M.
  TITLE     The stacking tryptophan of galactose oxidase: a second-coordination
            sphere residue that has profound effects on tyrosyl radical
            behavior and enzyme catalysis
  JOURNAL   Biochemistry 46 (15), 4606-4618 (2007)
   PUBMED   17385891
REFERENCE   2  (residues 1 to 639)
  AUTHORS   Akyumani,N., Tamber,S., Firbank,S.J., Knowles,P.F., Phillips,S.E.
            and McPherson,M.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2007)
COMMENT     Crystal Structure of Galactose Oxidase mutant W290F.
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Fusarium graminearum"
                     /db_xref="taxon:5518"
     Region          join(1..170,492..537)
                     /region_name="Domain 1"
                     /note="NCBI Domains"
     Region          4..134
                     /region_name="FA58C"
                     /note="Coagulation factor 5/8 C-terminal domain, discoidin
                     domain; Cell surface-attached carbohydrate-binding domain,
                     present in eukaryotes and assumed to have horizontally
                     transferred to eubacterial genomes; cd00057"
                     /db_xref="CDD:238014"
     SecStr          14..19
                     /sec_str_type="sheet"
                     /note="strand 1"
     Bond            bond(18,27)
                     /bond_type="disulfide"
     Het             join(bond(29),bond(32),bond(34),bond(37),bond(37),
                     bond(141),bond(142))
                     /heterogen="(NA,4827)"
     SecStr          38..41
                     /sec_str_type="sheet"
                     /note="strand 2"
     Site            order(40,73,80)
                     /site_type="other"
                     /note="sugar binding site [chemical binding]"
                     /db_xref="CDD:238014"
     SecStr          52..59
                     /sec_str_type="sheet"
                     /note="strand 3"
     SecStr          62..65
                     /sec_str_type="sheet"
                     /note="strand 4"
     SecStr          66..72
                     /sec_str_type="sheet"
                     /note="strand 5"
     SecStr          83..91
                     /sec_str_type="sheet"
                     /note="strand 6"
     SecStr          100..105
                     /sec_str_type="sheet"
                     /note="strand 7"
     SecStr          111..116
                     /sec_str_type="sheet"
                     /note="strand 8"
     SecStr          118..123
                     /sec_str_type="sheet"
                     /note="strand 9"
     SecStr          124..130
                     /sec_str_type="sheet"
                     /note="strand 10"
     SecStr          137..140
                     /sec_str_type="sheet"
                     /note="strand 11"
     SecStr          141..148
                     /sec_str_type="sheet"
                     /note="strand 12"
     Region          <156..314
                     /region_name="NanM"
                     /note="N-acetylneuraminic acid mutarotase [Cell
                     wall/membrane/envelope biogenesis]; COG3055"
                     /db_xref="CDD:442289"
     SecStr          158..162
                     /sec_str_type="sheet"
                     /note="strand 13"
     SecStr          163..168
                     /sec_str_type="sheet"
                     /note="strand 14"
     Region          join(171..223,538..639)
                     /region_name="Domain 2"
                     /note="NCBI Domains"
     SecStr          172..179
                     /sec_str_type="sheet"
                     /note="strand 15"
     SecStr          180..189
                     /sec_str_type="sheet"
                     /note="strand 16"
     SecStr          201..209
                     /sec_str_type="sheet"
                     /note="strand 17"
     SecStr          211..220
                     /sec_str_type="sheet"
                     /note="strand 18"
     Region          224..381
                     /region_name="Domain 3"
                     /note="NCBI Domains"
     SecStr          227..235
                     /sec_str_type="sheet"
                     /note="strand 19"
     Region          236..513
                     /region_name="NanM"
                     /note="N-acetylneuraminic acid mutarotase [Cell
                     wall/membrane/envelope biogenesis]; COG3055"
                     /db_xref="CDD:442289"
     SecStr          237..245
                     /sec_str_type="sheet"
                     /note="strand 20"
     SecStr          249..256
                     /sec_str_type="sheet"
                     /note="strand 21"
     SecStr          257..263
                     /sec_str_type="sheet"
                     /note="strand 22"
     Region          270..314
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Het             join(bond(272),bond(496),bond(581))
                     /heterogen="(CU1,4828)"
     SecStr          275..279
                     /sec_str_type="sheet"
                     /note="strand 23"
     SecStr          281..287
                     /sec_str_type="sheet"
                     /note="strand 24"
     SecStr          298..305
                     /sec_str_type="sheet"
                     /note="strand 25"
     SecStr          306..313
                     /sec_str_type="sheet"
                     /note="strand 26"
     SecStr          335..341
                     /sec_str_type="sheet"
                     /note="strand 27"
     SecStr          343..349
                     /sec_str_type="sheet"
                     /note="strand 28"
     SecStr          352..360
                     /sec_str_type="sheet"
                     /note="strand 29"
     SecStr          362..374
                     /sec_str_type="sheet"
                     /note="strand 30"
     SecStr          375..378
                     /sec_str_type="sheet"
                     /note="strand 31"
     Region          382..491
                     /region_name="Domain 4"
                     /note="NCBI Domains"
     SecStr          384..392
                     /sec_str_type="sheet"
                     /note="strand 32"
     SecStr          393..402
                     /sec_str_type="sheet"
                     /note="strand 33"
     SecStr          407..412
                     /sec_str_type="sheet"
                     /note="strand 34"
     SecStr          413..419
                     /sec_str_type="sheet"
                     /note="strand 35"
     SecStr          426..431
                     /sec_str_type="sheet"
                     /note="strand 36"
     SecStr          442..448
                     /sec_str_type="sheet"
                     /note="strand 37"
     SecStr          450..456
                     /sec_str_type="sheet"
                     /note="strand 38"
     SecStr          459..462
                     /sec_str_type="sheet"
                     /note="strand 39"
     SecStr          472..478
                     /sec_str_type="sheet"
                     /note="strand 40"
     SecStr          481..487
                     /sec_str_type="sheet"
                     /note="strand 41"
     SecStr          495..503
                     /sec_str_type="sheet"
                     /note="strand 42"
     SecStr          505..513
                     /sec_str_type="sheet"
                     /note="strand 43"
     Bond            bond(515,518)
                     /bond_type="disulfide"
     SecStr          523..531
                     /sec_str_type="sheet"
                     /note="strand 44"
     Region          538..637
                     /region_name="E_set_GO_C"
                     /note="C-terminal Early set domain associated with the
                     catalytic domain of galactose oxidase; cd02851"
                     /db_xref="CDD:199882"
     SecStr          544..550
                     /sec_str_type="sheet"
                     /note="strand 45"
     SecStr          552..556
                     /sec_str_type="sheet"
                     /note="strand 46"
     SecStr          557..566
                     /sec_str_type="sheet"
                     /note="strand 47"
     SecStr          569..580
                     /sec_str_type="sheet"
                     /note="strand 48"
     SecStr          586..592
                     /sec_str_type="sheet"
                     /note="strand 49"
     SecStr          594..597
                     /sec_str_type="sheet"
                     /note="strand 50"
     SecStr          600..607
                     /sec_str_type="sheet"
                     /note="strand 51"
     SecStr          615..624
                     /sec_str_type="sheet"
                     /note="strand 52"
     SecStr          633..639
                     /sec_str_type="sheet"
                     /note="strand 53"
ORIGIN      
        1 asapigsais rnnwavtcds aqsgnecnka idgnkdtfwh tfygangdpk pphtytidmk
       61 ttqnvnglsm lprqdgnqng wigrhevyls sdgtnwgspv asgswfadst tkysnfetrp
      121 aryvrlvait eangqpwtsi aeinvfqass ytapqpglgr wgptidlpiv paaaaiepts
      181 grvlmwssyr ndafggspgg itltsswdps tgivsdrtvt vtkhdmfcpg ismdgngqiv
      241 vtggndakkt slydsssdsw ipgpdmqvar gyqssatmsd grvftiggsf sggvfeknge
      301 vyspssktwt slpnakvnpm ltadkqglyr sdnhawlfgw kkgsvfqagp stamnwyyts
      361 gsgdvksagk rqsnrgvapd amcgnavmyd avkgkiltfg gspdyqdsda ttnahiitlg
      421 epgtspntvf asnglyfart fhtsvvlpdg stfitggqrr gipfedstpv ftpeiyvpeq
      481 dtfykqnpns ivrvyhsisl llpdgrvfng ggglcgdctt nhfdaqiftp nylynsngnl
      541 atrpkitrts tqsvkvggri tistdssisk aslirygtat htvntdqrri pltltnnggn
      601 sysfqvpsds gvalpgywml fvmnsagvps vastirvtq
//
bond(18,27)
/bond_type="disulfide"
Feature 2EIC_A : 2 segments
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